Principal Scientist (Team Manager)

Piramal is looking for a Team-leader/Principal Development Scientist responsible for leading method development, validation, Technical lead for projects ranging from lab-scale to toxicology development and pre-GMP technology transfer. The role will involve both technical and team leadership. The ideal candidate will possess both a strong technical background, and the proven ability (or potential) to lead and develop team of scientists. A track record of delivering project commitments on time is essential.

You will have the opportunity to work with a highly skilled and dedicated team who bring Antibody-Drug Conjugate to patients.. We pride ourselves on serving our customers and patients by developing and manufacturing novel life-saving pharmaceutical products.

The Role:

Chief Accountabilities & Responsibilities

• Daily Work:
• Responsible for project deliverables in line with agreed objectives and timelines.
• Provide technical support and advice for manufacturing activities relating to processes developed or transferred into Piramal.
• Responsibility for analytical / process conclusions reported.
• Daily leadership of small development team across multiple projects
• Mentoring of Scientists and direct line management responsibility
• Quality:
• Follow protocols and procedures
• Improve and challenge Quality systems and current procedures – strive for improvements
• Regulatory understanding and compliance
• Manufacturing Support:
• Support / guidance for first time manufacturing operations, troubleshoot scale-up
• Housekeeping / ESH
• Ensure safety and hygiene standards are maintained
• Comply with COSHH and Risk assessments
• Training
• Manages staff utilisation, training and development

Critical Tasks

• Managing scope and milestones (timelines)
• Managing project budgets
• Accuracy of raw data and analytical interpretations
• Client interaction / interface at front of business and new project enquiries.
• Provide technical support relating to processes developed or transferred into Piramal.

Key Result Areas & Measures (Quantitative/KPI/Qualitative)

• Delivery of development projects on time, in budget and to agreed quality measures.
• Client interactions and new proposal / project interactions

Critical Skills

• Protein modification and Conjugation Chemistry techniques, ADC purification
• Process robustness and optimisation studies
• Product characterisation of Final Product
• Analytical characterisation of Bioconjugates
• To provide technical expertise on bioconjugation programmes
• Data interpretation, presenting/reporting conclusions and recommendations
• Excellent communication skills
• Good working relationships with all internal colleagues, across departments, and external clients
• A proven track record of planning and delivering development work programmes
• Independent and analytical thinking