Principal Scientist

🔬 Senior/Principal Scientist – TCR Engineerin

Location:London |Type:Full-time |Sector:Biotech

A pioneering biotech client is seeking aSenior or Principal Scientistto lead the development and validation of next-generation T-cell receptor (TCR) therapies targeting solid tumours. This role is central to advancing a novel trispecific TCR-based T cell engager (TCE) platform.

Key Responsibilities:

• Leadin vivoandin vitrovalidation of TCEs.
• Design, express, and characterise TCRs for therapeutic programs.
• Conduct protein purification, biophysical analysis, and molecular biology workflows.
• Support immunoassays (e.g., flow cytometry, ELISA) and NGS data analysis.
• Collaborate across R&D and external partners to drive innovation.

Requirements:

• PhD in Immunology, Cell Biology, Biochemistry, or related field.
• Senior:1–2 years post-PhD experience |Principal:3+ years in industry.
• Proven experience with TCE validation, ideally through IND stage.
• Strong background in molecular biology, protein science, and immunological assays.
• Familiarity with NGS and data analysis tools (e.g., R) is a plus.

About Planet Pharma:

Planet Pharma is an American parented Employment Business/Agency that provides global staffing services with its head-quarters in Chicago and our EMEA regional office located in Central London. We have invested significantly in creating a robust international platform that enables us to work compliantly in 30+ countries with a current network of 2500+ active contractors globally as well as a very strong permanent / direct hire recruitment offering.

Our specialist knowledge and close relationships with our clients and the wider industry really makes us unique in our field. Just recently we were recognised by FORBES as the 17th best professional staffing firm, and have won multiple awards from industry accredited bodies for our commitment to excellence and service delivery. We have extensive functional expertise including: Regulatory Affairs, Pharmacovigilance, QA, QC, Submissions experts, Clinical development, Quality, Biostatistics, and Medical Affairs / Writing.

We are an equal opportunities Recruitment Business and Agency. We welcome applications from all suitably qualified candidates regardless of their race, sex, disability, religion/belief, sexual orientation or age.

www.planet-pharma.com