Biotechnology Jobs in Oxford

CureAge Therapeutics · London

Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.

Lypo · Edinburgh · £31,000 – £36,000 pa

Implement high-throughput plasmid assembly, colony PCR, Minipreps and pathway construction to build strains for hypothesis testing and model training. Work across disciplines in a lab-based, cross-pollinating team, with fortnightly research updates, mentorship and organised labbook/data keeping. Golden Gate assembly, Benchling in silico cloning and DNA sequencing are core.

Vertex Pharmaceuticals · Oxford

Lead the DMPK team at Vertex's Oxford site, shaping strategy and operations while sitting on both the Global DMPK and Oxford Site leadership teams. The role directs ADME science across discovery and development programmes, partners with Medicinal Chemistry, Biology, Preclinical Safety and Clinical Pharmacology, and oversees regulatory documentation such as INDs and marketing applications. It combines deep small-molecule DMPK expertise with hiring, mentoring and resource planning.

University of Oxford · Oxford · £40,178 – £48,700 pa

Conducts research characterising crosslinked proteins and lipids under a Wellcome Trust-funded grant, using proteome and lipidome methods including sample preparation, LCMS and data analysis. Manages project administration, guides junior researchers and students, and contributes to reports, publications and external seminars.

University of Oxford · Oxford · £36,360 – £42,434 pa

Supports an experimental programme building predictive models of cells, maintaining mammalian cell systems and running workflows such as endogenous protein tagging, CRISPR perturbation, optical pooled screening, live-cell imaging and proteomics. Works with computational and experimental researchers, generating engineered cell models and analysing data within a collaborative lab.

Genomics · London

Owns the transition from discovery to delivery on Mystra, a scientific data platform, breaking strategic initiatives into well-scoped epics and features. Works with scientific SMEs, data services, engineering and design to ensure requirements are scientifically valid and technically sound, running kick-offs and bi-weekly check-ins. Requires fluency with genomic data such as GWAS papers, p-values and effect sizes.

OMass Therapeutics · Oxford

You will apply DMPK expertise within multi-disciplinary project teams to solve drug discovery challenges and deliver high-quality candidate molecules into development. The role sits in a biotech using native mass spectrometry and custom chemistry against membrane proteins and intracellular complexes, working in state-of-the-art laboratories in Oxford.

GSK · London

Lead complex oncology projects, designing and interpreting scientific and clinical strategies while guiding cross-functional teams on technical and regulatory matters. The role combines hands-on project leadership with mentoring colleagues and driving new methodologies, in a hybrid setup spanning London and Upper Providence.

GSK · USA - Pennsylvania - Upper Providence

Lead complex oncology projects, designing and interpreting scientific and clinical strategies while collaborating with cross-functional teams and external partners. Provide expert guidance on scientific, technical and regulatory matters, drive innovation in methodologies, and mentor colleagues. Hybrid role split between London and Upper Providence, Pennsylvania.

Vertex Pharmaceuticals · Oxford

Embedded within multidisciplinary research teams at a fast-paced Oxfordshire site, contributing to drug discovery from target validation through small molecule discovery and optimisation. The placement offers hands-on laboratory work, disease biology exposure and development of practical scientific skills alongside other students.

The University of Manchester · Manchester · £38,448 – £46,970 pa

Lead mass spectrometry-based proteomics within a Wellcome Discovery Award consortium studying microbial competition and Type VI Secretion Systems. Design and run DIA proteomics experiments, maintain timsTOF and LC instrumentation, and apply R-based analysis pipelines, publishing findings as lead or co-author.

Moderna · Oxford

Sole-contributor scientist role developing and executing biochemical and molecular biology assays for PK/PD analysis, spanning genomic DNA/RNA isolation, qPCR, ddPCR, RNA sequencing, MSD, ELISA and immunoblotting. Works within Moderna's Clinical Bioanalytical team at Harwell, Oxfordshire, ensuring GcLP-compliant assay qualification and validation, troubleshooting with external CRO partners, and building internal and external mRNA-based bioanalytical capability.

Fortrea · Maidenhead

Monitoring investigator sites across the North of England for a routine post-market surveillance study within a dedicated FSP model. Involves on-site and remote monitoring, building relationships with investigators, and ensuring patient safety, data quality and regulatory compliance, with travel to Oxford at least monthly plus on-site onboarding and training.

Agilent · Didcot

Lead a team of software engineers delivering next-generation Raman spectroscopy software from the Laser Spectroscopy Center of Excellence in Oxford (Harwell). The role owns R&D operations across the software product lifecycle, solving engineering challenges and integrating hardware and software with global partners, using modern architectures such as containerisation, Kubernetes, microservices and cloud deployment.

Ellison Institute of Technology · Oxford · £40,000 pa

Develops and optimises LC-MS workflows for low-input and single-cell proteomics and/or metabolomics, supporting researchers across the institute with experiment design, method development, data acquisition and interpretation. Works closely with bioinformatics, scientific computing and AI/ML teams, and helps build SOPs and training material for single-cell MS capability.

Ellison Institute of Technology · Oxford · £40,000 pa

Postdoctoral role in the Liu Lab for Synthetic Evolution, designing and troubleshooting experiments, analysing complex data with computational and statistical tools, and publishing high-quality research. The lab invented OrthoRep for continuous accelerated gene evolution, with projects spanning antibody sequence-affinity datasets, enzyme sequence-function maps, and de novo gene function emergence. Involves mentoring junior researchers and collaborating across multidisciplinary teams.

University of Exeter · Exeter

A cross-institutional PhD studentship analysing whole genome sequencing data from millions of individuals across UK Biobank, All of Us and Our Future Health to identify rare causal variants for musculoskeletal disorders, then functionally validating them in human cell and tissue models using CRISPR-Cas9, transcriptomics and cellular phenotyping. Split between computational genomics at Exeter and laboratory work at Oxford, it develops a dual skill set in statistical genetics and experimental validation.