Principal / Senior Scientists - Pharmacologist (Oncology. Respiratory and Infection Models)

Location: Hatfield, Hertfordshire, UK
Position Type: Full-time
Seniority: Senior Scientist / Principal Scientist (based on experience)
Salary: Competitive, dependent on experience
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About Pharmidex:
Pharmidex is a respected, science-led preclinical CRO, supporting global biotech and pharmaceutical clients in drug discovery and development. Pharmidex team have contributed to more than 15 drugs at different stages of clinical development. With an expanding portfolio across Respiratory, Oncology, and Infectious diseases, we are growing our preclinical team to meet increasing demand for high-quality, translational studies.
This is an exciting opportunity for a motivated Senior or Principal Scientist to lead the establishment and execution of innovative translational preclinical models, contribute to client success, and shape the future of preclinical research at Pharmidex.
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Key Responsibilities:
• Take a lead role in establishing, developing, and validating preclinical models in-house – with a focus on respiratory disease, oncology, and infection.
• Serve as Study Director, managing studies from planning and execution through to data reporting and scientific interpretation.
• Coordinate and maintain a safe, compliant, and well-organised laboratory environment.
• Support and supervise technical staff across all preclinical projects.
• Engage with clients and collaborators to ensure successful delivery of studies and ongoing relationships.
• Contribute to internal project reviews, innovation initiatives, and cross-functional discussions.
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Your Background:
• Degree (BSc/MSc/PhD) in Biological Sciences, Pharmacology, or a related life sciences discipline.
• Minimum 3 - 5 years of hands-on preclinical experience in a pharma, biotech, or academic translational research setting.
• Demonstrable experience in developing and running preclinical Respiratory or Oncology models.
• Hold or have previously held a Home Office Personal Licence (PIL Modules 1–3 or equivalent).
• Proven ability to work in multi-disciplinary teams and independently manage projects.
• Familiarity with preclinical techniques including multiple administration routes.
• Competent in data analysis using GraphPad Prism, SPSS, or similar software.
• Experience of managing large and complex studies with good documentation and planning skills.
• Flexible and willing to conduct occasional out-of-hours work to meet study needs.
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Desirable (not essential):
• Experience with preclinical imaging techniques (e.g. IVIS, microCT).
• Practical expertise in cell culture or ex-vivo sample analysis.
• Background in GLP or regulatory-aligned studies.
• Previous exposure to client-facing roles or project oversight in a CRO setting.
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Why Join Pharmidex?
• Opportunity to work on diverse and impactful preclinical studies.
• Be part of a growing team where your expertise will help shape model development and client delivery.
• Flexible and collaborative culture with exposure to cross-disciplinary science.
• Career development aligned with company growth.
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What We Offer:
Competitive salary based on experience
Defined career development path with mentorship and training support
Company pension scheme with employer contribution
Life insurance (4x annual salary)
Employee perks and discounts platform
Free onsite parking and subsidised staff canteen
Opportunities to volunteer and contribute to social impact projects
Being part of a purpose-driven company that works with over 300 clients globally, including top pharma and emerging biotechs
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Salary: Depending on experience

Application Deadline: 04 August 2025

How to Apply:
If you are passionate about translational science and ready to make an impact in improving patients lives please send your CV and a short cover note to