Biotechnology Jobs

• London
• Hybrid
• Entry level
• Permanent

Early-career scientist role in a Life Sciences team, generating therapeutic hypotheses by mining in-house genomic data with statistical methods to identify and triage drug targets. Also develops and optimises polygenic risk score tools for patient stratification, working with omic data using statistical and AI/ML approaches and communicating findings to internal and external stakeholders.

Git · GitHub · WDL +4

• Cambridge
• On-site
• £45,000 – £50,000 pa
• Senior
• Permanent

Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.

CRISPR/Cas9 · Recombinase-Mediated Cassette Exchange · Bxb1 +3

• Oxford
• On-site
• £40,000 pa
• Senior
• Permanent

Develops and optimises LC-MS workflows for low-input and single-cell proteomics and/or metabolomics, supporting researchers across the institute with experiment design, method development, data acquisition and interpretation. Works closely with bioinformatics, scientific computing and AI/ML teams, and helps build SOPs and training material for single-cell MS capability.

LC-MS · Flow Cytometry · Sequencing +5

• Oxford
• On-site
• Entry level
• Permanent

Hands-on laboratory role supporting microbiology, molecular biology, sample processing and sequencing within the Pathogen Applications Team. Involves receiving and tracking clinical samples, preparing microbial cultures, running qPCR and sequencing workflows, and maintaining QC and documentation. Suits an early-career scientist with practical lab experience in a diagnostic or high-throughput environment.

Sequencing · Oracle Cloud

• Salt Lake City, United States
• Mid-level
• Contract

Develop, optimize and validate cell-based and biochemical assays for automated high-throughput screening, running workflows at scale across 384- and 1536-well formats. Work in a cross-disciplinary team with biologists, automation and data scientists, documenting methods so assays transfer reliably. A 9-month contractor role, Monday to Friday, 9am-5pm.

Liquid Handlers · Plate Readers · Imagers +5

• Oxford
• On-site
• Senior

Sole-contributor scientist role developing and executing biochemical and molecular biology assays for PK/PD analysis, spanning genomic DNA/RNA isolation, qPCR, ddPCR, RNA sequencing, MSD, ELISA and immunoblotting. Works within Moderna's Clinical Bioanalytical team at Harwell, Oxfordshire, ensuring GcLP-compliant assay qualification and validation, troubleshooting with external CRO partners, and building internal and external mRNA-based bioanalytical capability.

MSD · LIMS · eLNB +1

• Portsmouth
• On-site
• Entry level
• Permanent

Performs laboratory test work in line with SOPs, recording raw data and flagging delays or deviations to management. Reviews testing requirements and safety data, troubleshoots instrumentation, and helps maintain lab systems such as purchasing, calibration and materials inventory. Based on-site in Portsmouth within a validation and lab operations team.

• Oxford
• On-site
• Senior · manages people

Lead development, qualification, validation and execution of complex cell-based immunoassays generating clinical trial data across therapeutic areas. Act as scientific point of contact within the Immuno-assays group, performing GCP/GLP-compliant sample testing, authoring validation reports, and mentoring junior lab staff. Fully onsite at Harwell, reporting to the Associate Director, Immuno-assay UK.

GraphPad Prism · Microsoft Word · Microsoft Excel +2

• Stevenage
• On-site
• Mid-level

Performs complex sample preparation and quantitative analysis of small molecules and biotherapeutics using instrumentation such as GC-MS, ICP-OES, HPLC and LC-MS, supporting both GMP and non-GMP stability studies. Works largely independently to set up, maintain and troubleshoot analytical instrumentation, interpret data for technical validity and compliance, and report results to client teams. Based full-time onsite at a pharmaceutical client site as part of a functional service provider partnership.

GC-MS · ICP-OES · HPLC +2

• Stevenage
• Lead

Develops and deploys cheminformatics and machine learning models on large proprietary datasets to guide go/no-go decisions across drug-discovery programmes. Embeds predictive models into multidisciplinary teams spanning DMPK, toxicology and safety pharmacology, and prototypes LLM-driven agent workflows for design-make-test-analyse cycles.

ChemAxon · RDKit · Pipeline Pilot +2

• Waltham, United States
• On-site
• US$150,975 – US$251,625 pa
• Mid-level

Key member of the Clinical Development team contributing to the design, execution, analysis and reporting of clinical studies across all phases. Works cross-functionally with Medical Monitoring, Clinical Operations, Biostatistics, Data Management and Regulatory Affairs, reviewing safety, efficacy, biomarker and PK/PD data and supporting CSRs and regulatory submissions. Based on-site in Waltham, MA or London, UK.

• Aylesbury
• £23 ph

Job summaryWe have an exciting opportunity for a Biomedical Scientist Microbiology at Buckinghamshire Healthcare NHS Trust to join the Microbiology Department at Stoke Mandeville Hospital. You will be responsible for performing specialist microbiology and serology investigations in accordance with departmental…

• Cambridge
• On-site
• £20 – £24 ph
• Mid-level
• Temporary

Undertake routine and specialist microbiological and molecular investigations across bacteriology, Containment Level 3, serology, chlamydia and molecular diagnostics, interpreting and reporting results. Operate and maintain automated analysers, manage consumables and lab IT systems, and contribute to quality management, audits and SOP development. Based at Addenbrooke's Hospital within UKHSA's Public Health Microbiology team.

UKAS · HSE

• London
• Hybrid · 3 days in office
• Senior · manages people

You will design and develop LLM applications for drug discovery, working with research scientists and engineers on model architectures, post-training, reasoning, agents and reinforcement learning. The role spans core ML research, scaling training and inference frameworks, and potentially leading standalone projects with technical mentorship.

JAX · PyTorch · TensorFlow +3

• London
• Hybrid · 3 days in office
• Senior · manages people

Builds greenfield machine learning models and algorithms for drug discovery, designing new architectures, running experiments and scaling training and inference frameworks. Works in an interdisciplinary team of ML scientists and domain experts, with opportunities to lead projects and mentor others depending on experience.

JAX · PyTorch · TensorFlow +3