Senior Toxicologist

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Myricx Bio (“Myricx”) is a pioneering global biotech company advancing innovative antibody-drug conjugates (ADCs) that deliver inhibitors of N-myristoyltransferase (NMT). We are a small but rapidly growing team, with a vision to advance a pipeline of ADCs based on our novel NMTi payload chemistry platform. This novel mechanism-of-action holds significant promise for treating cancer and other diseases.

As leaders in NMT biology and NMT inhibitors, Myricx successfully raised £90 million ($114 million) in Series A financing in 2024 to advance our pipeline of ADC therapeutics. We are currently seeking to recruit a Senior Toxicologist. In this key role the successful candidate will oversee the overall strategy and execution of the nonclinical toxicology program, collaborating cross-functionally and providing data interpretation at various internal and external venues, and authoring regulatory documents.

Role Overview:

• Support development project teams with studies to enable early and late-phase clinical development.
• Support research teams with respect to early toxicological target assessment and early toxicology screening tools
• Design, manage, review, interpret and report fully outsourced toxicology and safety studies autonomously and productively, maintaining and building strong interactions with CROs.
• Prepare and review toxicology and safety pharmacology parts of regulatory documents (IND, CTD, IMPD, IB, briefing books etc.)
• Participate in due diligences as preclinical safety expert
• Accountable for timely analysis and interpretation of toxicology & safety pharmacology data (in silico, in vitro and in vivo)
• Participate in internal and external scientific communications (oral presentations, posters, publication).
• Work closely with cross departmental teams

Requirements:

• A degree (BSc, MSc or PhD in Toxicology or another relevant scientific discipline)
• Solid toxicology background with strong experience gained in the pharmaceutical industry or contract research organisation (CRO) environment
• Experience working with ADCs and other drug conjugates will be highly favoured.
• Knowledge of applicable regulatory guidelines and legislation
• Knowledge in preclinical research, including animal and in vitro studies
• Excellent communication and presentation skills (oral and written)
• Ability to influence through the matrix, demonstrated assertiveness and impact in communication
• Experienced in scientific writing and project management/study conduct oversight
• Fluent in business English language skills in speaking and writing,
• Excellent organisation and time management skills to successfully initiate and coordinate fully outsourced studies
• Good IT and analytical skills

What’s in it for you? Why work at Myricx

We are a small but rapidly growing team, with a vision to advance a pipeline of ADCs based on our novel NMT inhibitor (NMTi) payload chemistry platform to address serious unmet needs in oncology. As an early joiner, you will have a unique opportunity to help shape our trajectory and make real impact from day one.

Myricx is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

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