Role

Senior Analytical Chemist

Location

Alderley Park, Cheshire, England

Job Type

Permanent 

Salary

£35,000 - £55,000 depending on experience

Date posted

21stDecember 2024

Start date

ASAP

The Company

Sai Life Sciences is a leading global Contract Research & Development and Manufacturing Organisation (CDMO) that provides integrated drug substance services to the biotech and pharmaceutical industries. With expanded process development labs in Manchester, UK & Hyderabad, India, and increased commercial manufacturing capacity in Bidar, India, Sai is working with 17 of the top 20 pharma companies globally, as well as many leading smaller biotechs. We work with our clients to accelerate the discovery, development and manufacture of complex small molecules for a healthier tomorrow. With more than 3000 staff globally and ambitious growth plans, our vision is to support our global innovator partners to bring 25 new medicines to life by 2025.

In 2019 the company began an organisation-wide initiative to significantly expand and upgrade its R&D and manufacturing facilities, deepen scientific & technological capabilities, strengthen automation and data systems, and above all raise the bar for safety, quality and customer focus. Guided by the insights and feedback from its customers, it committed to investing over US$150M between 2019 and 2023. Part of this investment in 2020 were the new state-of-the-art laboratories in our centre of excellence for process chemistry and analytical development at the Alderley Park Science Park, situated on the outskirts of Manchester. Our overall team currently consists of >60 multi-disciplinary scientists (chemists, analysts and engineers).

Non-GMP manufacture of kg quantities of intermediates and APIs is currently possible within our bespoke Scale-up laboratory facility and a new GMP Kilo-lab facility was brought online in 2023 capable of kg quantities of GMP API suitable for early phase clinical studies. Developed processes are frequently transferred to Sai’s manufacturing sites in India for further scale-up when required.

The role will be based in Alderley Park, Cheshire, UK and will require right to work in the UK. Occasional travel, domestic and international to India is optional.

The Role

·      You will join a team that identifies, develops and optimises synthetic routes and processes to APIs, supporting both early and late phase development.

·      To support chemistry projects, through analytical lab-based work, develop, validate and carry out technical transfer of analytical methods, release analysis, as well as providing analytical expert advice to Process Chemistry colleagues.

·      To provide support to analytical instrumentation in a GMP environment

Essential Requirements

·      The successful candidate will have a strong technical grounding in Analytical Chemistry with a minimum of 3 years’ experience in a relevant analytical chemistry role in industry.

·      Experience in developing and troubleshooting LC and GC methods.

·      Experience in other analytical methodologies such as techniques for identity or form determination (NMR, MS, IR, XRD).

·      Strong scientific track record.

Desirable Requirements

·      Understanding of GMP quality standards.

·      Demonstrated analytical expertise supporting early, mid or late-phase route and process development of APIs, intermediates and raw materials.

Key Roles and Responsibilities

·      Developing, troubleshooting and validating analytical methodology.

·      Working within multi-functional project team operating to tight deadlines.

·      Planning and executing analytical work to meet project timelines with minimal supervision.

·      Ability to work effectively in a GMP laboratory.

Key Attributes

·      Learning agility in the utilisation of new techniques to support projects.

·      Ability to solve complex scientific problems.

·      Excellent communication; both verbal and written.

o   This includes the ability to accurately detail laboratory experimentation in an electronic notebook and ability to write clear and concise project reports and slides as required.

·      A team player.

·      Conscientious with a can-do attitude with good attention to detail.

·      Experience in the use of IT packages such as Word and Excel, as well as in Analytical Data systems such as Empower 3 or UNIFI. Understanding and experience of LIMS would also be advantageous.  

The Offer

·      A competitive Salary and Benefits package including company pension, health and life insurance, 25 days holiday per year and enhanced family leave. 

·      Work in a state-of-the-art facility on one of the country's leading Biotech & Life Science Parks.

·      Flexible working hours and conditions to suit the right candidate.

Next steps

Please send your CV and cover letter towith details of the role that you are applying for.

As an Equal Opportunities employer, we welcome applications from all suitably qualified persons regardless of their race, sex, disability, religion/belief, sexual orientation or age.

Please note that Sai Life Sciences Ltd is unable to sponsor the visas for any candidates for the above role.