Jobs in Cambridge

Director of Clinical Pharmacology, Cambridge, MA

Lead clinical pharmacology strategy for small molecule programs in oncology and non-oncology areas, designing and executing studies from Phase 1 through late development. Utilize AI-driven models for PK/PD prediction, dose optimization, and regulatory submissions, while managing CROs and translating preclinical data into human dosing strategies.

Isomorphic Labs Cambridge, United Kingdom

Director of Nonclinical Safety, Cambridge, MA

Lead the development and execution of nonclinical safety strategies for small molecule drug candidates in oncology and non-oncology programs, integrating AI-driven predictive models with traditional toxicology. Build and scale the nonclinical safety function within an AI-first drug discovery environment, ensuring high-quality data feedback to refine computational models. Collaborate across preclinical, clinical, and regulatory teams to advance compounds through IND and NDA/MAA-enabling studies.

Isomorphic Labs Cambridge, United Kingdom

Pathology Director

Leads medical and technical oversight of an accredited diagnostic laboratory supporting clinical trials and biomarker development. Provides expert interpretation of pathology and biomarker data, ensures regulatory compliance, and drives innovation in digital pathology and companion diagnostics. Works cross-functionally to integrate advanced diagnostic methods into drug development programs.

AstraZeneca Cambridge, United Kingdom

Translational Science Lead

Leads end-to-end translational strategies for respiratory disease programmes, integrating human biology, multi-omics data, and biomarker development to de-risk clinical decisions. Designs and implements target validation, patient stratification, and precision medicine approaches while collaborating across discovery, clinical, and data science teams. Drives biomarker strategy into clinical protocols and regulatory submissions, using AI/ML and innovative assays to generate actionable insights.

AstraZeneca Cambridge, United Kingdom

Head of Computational-Aided Drug Discovery

Leads a computational chemistry and data science team embedded in multidisciplinary drug discovery projects, applying AI, machine learning, and structure-based methods to drive hit identification and lead optimisation. Directs scientific strategy, develops workflows, and contributes hands-on to project teams using biophysical and structural data. Focuses on integrating modern computational techniques with experimental insights to advance pre-clinical candidates.

Pure Resourcing Solutions Great Abington, Cambridgeshire, United Kingdom £100,000 pa

Senior Mechanical Engineer

Design and develop advanced electro-mechanical systems for medical technology applications, from concept through to manufacture. Work within a multidisciplinary team to solve complex engineering challenges and ensure compliance with regulatory standards. Contribute to innovative products that have a real-world impact on healthcare.

AES Ely, Cambridgeshire, United Kingdom £50,000 – £75,000 pa

Hybrid Permanent

Head of Computational-Aided Drug Discovery

Leads a computational chemistry and data science team within a drug discovery environment, integrating structural data, machine learning, and AI to drive hit and lead identification. Works embedded in multidisciplinary project teams, applying advanced modelling techniques and guiding strategy from target to candidate nomination. Focuses on translating computational insights into tangible project progress using both in-house and commercial tools.

Pure Resourcing Solutions Cb216Gb, United Kingdom £100,000 pa

Senior / Staff Medical Firmware Engineer

Lead the design and development of safety-critical embedded firmware for next-generation insulin pump systems in a regulated medical device environment. Establish robust firmware lifecycle processes, ensure compliance with IEC 62304 and ISO 13485, and collaborate with cross-functional teams including Quality and Regulatory. Mentor engineers and shape technical direction while working on technology that directly improves patient outcomes.

Verso Recruitment Teversham, Cambridgeshire, United Kingdom

Consulting Engineer - Medical Device Development

This role involves acting as a technical advisor in early-stage business development for medical device innovation, bridging scientific expertise with commercial strategy. You'll engage with clients to understand their challenges, collaborate with engineers and scientists to develop technically sound proposals, and help convert ideas into market-ready solutions. The position supports cutting-edge projects such as implantable sensors, laser-based therapies, and non-invasive surgical technologies.

Newton Colmore Cambridge, Cambridgeshire, United Kingdom

Hybrid Permanent

Medical Device Programme Lead

Balance technical, regulatory and commercial challenges in this fulfilling roleThis highly regraded Cambridge-based medical technologies company is seeking a proven engineering leader to help guide high-value development programmes from concept through to transfer to manufacture. Your leadership will accelerate development...

ECM Selection Cambridge, Cambridgeshire, United Kingdom £75,000 – £95,000 pa

Senior Mechanical Engineer - Complex Sensor Design

Design and develop complex sensor-based devices and instruments from concept through to manufacturing and deployment. Work closely with world-class engineers and scientists on multidisciplinary research projects, taking hands-on responsibility for mechanical design and technical leadership within the team. Devices range from handheld units to large-scale systems for detecting and measuring various physical parameters.

Newton Colmore Cambridge, Cambridgeshire, United Kingdom £50,000 – £70,000 pa

Senior Medical Director, Oncology Clinical Development - Lung

This role involves leading clinical development strategy for oncology, specifically lung cancer, providing medical oversight across trial design, safety monitoring, and data interpretation. The Senior Medical Director will guide cross-functional teams, engage with external experts, and contribute to regulatory submissions, ensuring patient-centred, scientifically rigorous development. Based in the UK with hybrid working, the position plays a key leadership role in advancing GSK’s oncology pipeline.

GSK Stevenage, United Kingdom PLN 593,250 – PLN 988,750 pa

VP, Medicine Development Leader - Specialty Product Development

This role leads the global development of a medicine from clinical proof of concept to first-market approval, serving as the single point of accountability within GSK's matrixed R&D environment. The VP Medicine Development Leader will build and lead a cross-functional team, define strategic development plans, and ensure alignment with regulatory, commercial, and manufacturing stakeholders. The position emphasizes evidence-based decision-making, lifecycle planning, and patient-focused development across multiple indications.

GSK Stevenage, United Kingdom £242,250 – £403,750 pa

Associate Director / Director – Integrated Drug Discovery & Project Leadership

Lead multidisciplinary drug discovery projects from target validation through hit identification and lead optimisation, integrating biology, chemistry, DMPK, and translational sciences. Provide scientific and people leadership within a GPCR-focused discovery engine powered by structural biology and computational design. Drive innovation, portfolio progression, and team development in a fast-paced biopharma environment.

Talentmark Great Abington, Cambridgeshire, United Kingdom

Head of Computer-Aided Drug Discovery (CADD)

Lead a computational drug discovery team focused on structure- and fragment-based design, integrating AI/ML, cheminformatics, and advanced simulation methods into multidisciplinary drug discovery programmes. Drive computational strategy while maintaining hands-on involvement in projects from hit identification through to candidate nomination. Collaborate closely with medicinal chemistry, structural biology, and biophysics teams to deliver innovative therapeutics.

VRS UK Cambridge, Cambridgeshire, United Kingdom