Principal Scientist PKPD

Slough
2 weeks ago
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CK Group are recruiting for a Principal Scientist PKPD to join a global pharmaceutical company on a contract basis initially for 12 months.
 
Salary:
£35.20 Per hour (PAYE) / £47.92 (Umbrella) - flexible for experienced candidates.
 
Principal Scientist PKPD Role:

Participate in the development of non-clinical PKPD and GLP toxicokinetics studies. Lead the non-clinical PKPD strategy. Participate in protocol designs and writing by providing scientific support and input into regulatory study designs and protocols.
Work collaboratively with the project teams representatives (e.g. Non-Clinical Safety, Bioanalysis, Clinical Pharmacology) and with the CROs, to ensure high quality data is generated.
Deliver PKPD study reports and integrated summaries of the studies and participate in regulatory submission documents.
Facilitate the advancement of drug candidates by building a thorough knowledge of the drug pharmacology and PKPD.
Work collaboratively with the project teams representatives (e.g. Non-Clinical Safety, Bioanalysis, Clinical Pharmacology) and with the CROs, to ensure high quality data is generatedYour Background:

Experience working in a matrix environment, to help design and set non-clinical PKPD study protocols, and analyze, interpret, and report PKPD results including GLP toxicokinetics studies.
PhD/MSc/BSc relevant discipline (quantitative pharmacology; pharmacokinetics /pharmacodynamics; DMPK, etc.) with more than 5 years hands on experience in PKPD data analysis within a pharma company or CRO environment.
Good understanding of pharmacology and pharmacologic processes related to disease and drug mechanisms.
Hands-on experience in delivering high quality pre-clinical PKPD data analysis. Proficiency in the use of Phoenix- WinNonlin for PKPD analysis is essential. Use of other modelling and simulation packages and tools, such as Berkeley Madonna and/or R would be advantageous.
Good written and verbal communication skills, and ability to communicate study results and produce high standard reports that meet regulatory submission standards. Record of publications and other external scientific contributions relevant to PKPD will be a plus.Company:
Our client is a is a global biopharmaceutical company focused on creating value for people living with severe diseases in immunology and neurology now and into the future.
 
Location: 
This role is based at our client’s site in Slough.
 
Apply:
For more information, or to apply for this Principal Scientist PKPD, please contact the Key Accounts Team on (phone number removed) or email (url removed). Please quote reference (Apply online only).

It is essential that applicants hold entitlement to work in the UK
Please note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check

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