The role involves leading projects to develop and benchmark AI models for predicting biological processes using genomic, multi-omic, and phenotypic data. The researcher will also contribute to statistical analysis, hypothesis testing, and preparing grant applications.
This role involves establishing and running iPSC-derived kidney and ureteric bud organoid models, using CRISPR interference to perturb candidate cis-regulatory elements, and profiling the consequences using advanced techniques like single-nucleus multiomics and CUT&RUN. You will work collaboratively with bioinformaticians and clinicians to generate and test hypotheses, and have opportunities for advanced training and independent research.
This role involves supporting researchers with study design, data analysis, and training in molecular ecology and bioinformatics, particularly in metabarcoding, population genomics, and sequence assembly. The postholder will contribute to R&D activities within a large, interdisciplinary genomics laboratory serving around 70 researchers. Work includes handling DNA sequence datasets and utilising high-performance computing for complex analyses.
This role involves developing, qualifying, and validating molecular bioanalytical assays—such as qPCR, ddPCR, and RT-qPCR—to support clinical pharmacokinetic and pharmacodynamic studies within a GCLp-compliant environment. The scientist will work closely with cross-functional teams to ensure robust data generation, maintain regulatory compliance, and integrate emerging digital and automation technologies into workflows. A strong focus on reagent management, assay documentation, and continuous process improvement is central to the position.
This role involves developing, optimizing, and validating molecular bioanalytical assays—such as qPCR, ddPCR, and RNA isolation—to support mRNA-based clinical programs. The scientist will work within GCL0-compliant (GCLP) frameworks to generate pharmacokinetic and pharmacodynamic data, ensuring regulatory compliance and data integrity. Collaboration with cross-functional teams and adoption of digital tools and automation are key to advancing clinical trial execution and analytical processes.
This role involves leading independent research into the molecular mechanisms of transcription-replication conflicts in DNA, using biochemical and structural biology methods such as recombinant protein expression, in vitro assays, and potentially cryo-EM. The researcher will analyse complex datasets, contribute to high-impact publications, and collaborate within a team-focused environment at a world-leading university. The position offers the opportunity to work on a Wellcome Trust-funded project in state-of-the-art facilities with a strong emphasis on genome integrity and fundamental biological processes.
Develop high-throughput Python workflows to extract geometric, topological, and structural descriptors from coarse-grained molecular dynamics simulations of protein assemblies. Translate simulation data into design rules for hollow inorganic fibres, integrating computational analysis with experimental validation across an interdisciplinary team.
This role leads the design and delivery of transformation-ready vectors and genome editing reagents for crop improvement programs, focusing on molecular construct development for gene editing and transgenic approaches in species like corn and wheat. The position establishes industrial-grade design standards, ensures technical robustness and regulatory alignment, and integrates with high-throughput transformation pipelines. It involves close collaboration with genotyping, automation, and commercial teams to enable scalable, traceable, and auditable vector development from concept to release.
This role leads the molecular confirmation and genotyping of gene-edited and transgenic crop events, ensuring high-quality, data-rich handover to downstream teams. The candidate will establish stage-gate criteria, manage genotyping workflows across multiple technologies, and integrate with transformation, bioinformatics, and trait discovery teams. The position is central to building a scalable, industrial-grade pipeline for crop development in species such as corn and wheat.
This role involves conducting wet-lab research on antibody effector functions in hepatocellular carcinoma using preclinical models induced by hydrodynamic gene transfer. The researcher will manage in vivo experiments, analyse data, contribute to publications, and support grant applications within a Cancer Research UK-funded programme. The position is based at the Oxford Centre for Immuno-Oncology and plays a key role in developing novel antibody-based immunotherapies for solid tumours.
This role leads the statistical strategy for clinical development programs, overseeing study design, data analysis, and regulatory submissions. The individual will guide biostatistical input across trials, interact with regulatory authorities, and ensure accurate reporting of results. Collaboration with cross-functional teams and oversight of internal or outsourced programming efforts are key aspects of the position.
This role involves providing strategic statistical leadership for Health Technology Assessment, pricing, and reimbursement activities. The candidate will work with cross-functional teams to ensure HTA evidence is scientifically rigorous and aligned with payer requirements. Responsibilities include implementing HTA methods, contributing to evidence synthesis, and mentoring biostatisticians.
Support translational research by assisting in normothermic machine perfusion experiments and a range of laboratory techniques including cell culture, flow cytometry, and molecular biology. Contribute to gene therapy development using advanced in vitro models, with training provided and no prior perfusion experience required.
This role involves supporting research into arbovirus biology, focusing on chikungunya virus and related flaviviruses. The technician will use molecular and cell biology techniques such as PCR, cloning, RNAseq, and infectious clone systems to study viral genome regulation in human and mosquito cells. The work contributes to identifying antiviral targets within a multidisciplinary team at a leading UK research university.
Applications are invited for a Research Fellow in Optical Biomedical Instrumentation Development to join the Department of Medical Physics and Biomedical Engineering at University College London (UCL).The successful candidate will join the internationally renowned Biomedical Optics Research Laboratory (BORL) and...
