This postdoctoral position involves leading the preparation and analysis of skeletal muscle samples for proteomic and transcriptomic workflows, focusing on the 'dark proteome' in facioscapulohumeral muscular dystrophy (FSHD). The role combines technical leadership with broader involvement in translational research, collaborating with international partners.
The role involves conducting research on the biological mechanisms of fatigue and post-exertional symptom exacerbation in Long COVID. Responsibilities include participant recruitment, physiological assessments, biological sample collection, and project coordination, working closely with multidisciplinary teams.
The role involves leading projects to develop and benchmark AI models for predicting biological processes using genomic, multi-omic, and phenotypic data. The researcher will also contribute to statistical analysis, hypothesis testing, and preparing grant applications.
This role involves establishing and running iPSC-derived kidney and ureteric bud organoid models, using CRISPR interference to perturb candidate cis-regulatory elements, and profiling the consequences using advanced techniques like single-nucleus multiomics and CUT&RUN. You will work collaboratively with bioinformaticians and clinicians to generate and test hypotheses, and have opportunities for advanced training and independent research.
This role involves using ultra-long-read and hybrid sequencing technologies to explore highly repetitive DNA sequences in childhood cancer. You will develop laboratory protocols, produce sequencing data, and perform bioinformatic analysis with support from biostatisticians.
This role involves researching the emergence of a multidrug-resistant fungal pathogen, Trichophyton indotineae, at the intersection of genomics, antimicrobial resistance, and molecular diagnostics. You will work in a multidisciplinary team to develop new diagnostic tools and contribute to clinical and public health efforts in East London.
This role involves developing, qualifying, and validating molecular bioanalytical assays—such as qPCR, ddPCR, and RT-qPCR—to support clinical pharmacokinetic and pharmacodynamic studies within a GCLp-compliant environment. The scientist will work closely with cross-functional teams to ensure robust data generation, maintain regulatory compliance, and integrate emerging digital and automation technologies into workflows. A strong focus on reagent management, assay documentation, and continuous process improvement is central to the position.
This role involves developing a computational platform for malaria vaccine discovery, focusing on T-cell antigen and peptide prioritisation. You will work with large datasets, develop scalable workflows, and collaborate internationally to create reusable research outputs and scientific publications.
This role involves developing, optimizing, and validating molecular bioanalytical assays—such as qPCR, ddPCR, and RNA isolation—to support mRNA-based clinical programs. The scientist will work within GCL0-compliant (GCLP) frameworks to generate pharmacokinetic and pharmacodynamic data, ensuring regulatory compliance and data integrity. Collaboration with cross-functional teams and adoption of digital tools and automation are key to advancing clinical trial execution and analytical processes.
This role involves leading the contracting activities for clinical studies, negotiating agreements, and ensuring compliance with regulatory requirements. The Contracting Specialist will collaborate with various stakeholders to accelerate study activation and patient recruitment.
This role leads the design and delivery of transformation-ready vectors and genome editing reagents for crop improvement programs, focusing on molecular construct development for gene editing and transgenic approaches in species like corn and wheat. The position establishes industrial-grade design standards, ensures technical robustness and regulatory alignment, and integrates with high-throughput transformation pipelines. It involves close collaboration with genotyping, automation, and commercial teams to enable scalable, traceable, and auditable vector development from concept to release.
This role leads the molecular confirmation and genotyping of gene-edited and transgenic crop events, ensuring high-quality, data-rich handover to downstream teams. The candidate will establish stage-gate criteria, manage genotyping workflows across multiple technologies, and integrate with transformation, bioinformatics, and trait discovery teams. The position is central to building a scalable, industrial-grade pipeline for crop development in species such as corn and wheat.
This role involves applying and developing advanced machine learning and computer vision techniques to analyze multi-omic data and detect disease phenotypes. You will work closely with software engineers to translate research into practical tools, ensuring robustness and usability.
The Associate Director (Scientific Data and Publications) manages GSK's external scientific content and data licenses, ensuring cost-effective and compliant access to critical information. The role involves strategic portfolio management, vendor relationships, and leveraging AI for future needs.
This role involves managing GSK's portfolio of external scientific content and data licenses, ensuring cost-effective access to critical information for R&D. Responsibilities include budget management, vendor relationships, and compliance with copyright and licensing terms. The position also focuses on integrating AI and text-mining capabilities to enhance the value of licensed content.
