Biotechnology Jobs

CureAge Therapeutics · London

Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.

Alloy Therapeutics UK Ltd · Cambridge · £45,000 – £50,000 pa

Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.

Isomorphic Labs · London

Contribute to the design of novel large-molecule therapeutics by applying computational and machine learning methods to predict biologics properties such as affinity, developability and immunogenicity from sequence. Work within an interdisciplinary computational sciences team alongside ML and biologics discovery experts, benchmarking models, analysing lab data and shaping data-generation strategies for active learning.

SRG · Darlington · £65,000 – £85,000 pa

Lead multidisciplinary operational teams across two sites, covering operations, engineering, facilities and site services. Drive continuous improvement, GMP and H&S compliance, facilities management, budgets and capital projects supporting biologics, RNA and medicines manufacturing. Senior leadership role shaping facility strategy and operational capability.

Isomorphic Labs · London

Lead pharmacology and translational biology strategy for large molecule therapeutics, designing in vivo efficacy and complex in vitro functional assays. Act as Biology Lead on projects, coordinating internal workflows and external CROs, and collaborate with ML and computational biology teams to feed data into generative AI design loops.

Ipsen · Wrexham

Leads Ipsen's global Biologics Process Development organisation, owning CMC drug substance strategy for toxins, monoclonal antibodies, ADCs and enzymes from candidate selection through launch and lifecycle. Manages process and analytical development teams, acts as CMC sponsor, and directs CDMO partnerships, tech transfer and regulatory submissions. Also serves as PharmDev/R&D site lead in Wrexham on the cross-divisional Site Leadership Team.

Evotec · Macclesfield

Lead the design, engineering, expression, purification and characterisation of complex biologic therapeutics including monoclonal, bispecific and multispecific antibodies. Acts as biologics scientific lead on client-facing drug discovery programmes, mentoring junior scientists and shaping project strategy within a multidisciplinary Protein Sciences team.

Eurofins · Slough

Performs routine, non-routine and stability testing of biologic drug substances in a client's Analytical Service Department, running ELISA, cell-based and Biacore assays and capturing data in laboratory software and electronic notebooks. Generates and reviews GMP-compliant documentation, SOPs and protocols, supports method development and validation, and handles out-of-specification investigations while liaising with internal and external clients.

Eurofins · Slough

Performs routine, non-routine and stability testing of biologic drug substances using ELISA, cell-based potency assays and Biacore (SPR), while coordinating assay activities and managing project priorities and timelines. Acts as a technical subject matter expert, mentoring colleagues and supporting method development, validation, troubleshooting and GMP-compliant documentation within a client-facing analytical service department.

Hyper Recruitment Solutions · Durham

Lead multidisciplinary operations across Durham and Glasgow sites, overseeing pharmaceutical and biopharmaceutical manufacturing, process engineering and compliant facilities. The role covers GMP compliance, asset management, equipment validation, engineering change control, safety culture and business continuity, while shaping future capability in biologics, RNA and medicines manufacturing.

GSK · Stevenage · £119,250 – £198,750 pa

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late pre-candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work across small molecules, biologics and antibody drug conjugates, applying AI/ML and quantitative systems pharmacology methods. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

GSK · Waltham, United States · £188,100 – £313,500 pa

Leads model-informed drug development for oncology programs, defining and executing model-based strategies from late discovery through lifecycle management. Conducts population PK, exposure-response, simulation-based trial design and dose selection, applying AI/ML, quantitative systems pharmacology and model-based meta-analysis. Presents to governance boards and regulators and works across matrix teams on small molecules, biologics and antibody drug conjugates.

Moderna · London

Leads CMC regulatory strategy for global submissions including IND, CTA, BLA and MAA, and oversees agency correspondence and compliance for mRNA products. Reviews submissions for readiness, drives health authority interactions, and advises manufacturing and quality teams on change controls and regulatory guidance across vaccines, oncology and rare disease programmes.

Moderna · Oxford

Provides scientific and hands-on leadership for immunogenicity and ligand binding assay bioanalysis supporting mRNA-LNP therapeutic programs, spanning assay development, validation, clinical sample testing and regulatory submissions. Ensures GcLP compliance and partners with cross-functional teams, with opportunities to work alongside data and AI-enabled analytical approaches.

Vertex Pharmaceuticals · London

Oversees quality control testing for a genetically edited cell therapy, acting as lead point of contact for external CDMOs and QC labs on GMP release, stability and method lifecycle work. Leads OOS/OOT investigations, reference standards and assay controls programmes, authoring and approving SOPs, COAs and protocols. Hybrid role based in London requiring close collaboration with contract test labs and management on compliance risks.

Ipsen · Wrexham

Leads Cell Line Development and Upstream Process Development strategies for biologic products, from candidate selection through commercial manufacturing. Acts as subject matter expert within cross-functional CMC teams, managing CDMO partnerships, supporting regulatory submissions and technology transfer, and mentoring junior scientists.

Thermo Fisher Scientific · Stevenage

Primarily lab-based role operating single-use bioreactor systems to culture mammalian cells, mainly CHO lines, for upstream process research. Involves planning and troubleshooting seed train expansion, inoculation, feeding, sampling and harvest, then analysing growth, viability, metabolite and titre data. Works within a client-dedicated multidisciplinary team at a biopharmaceutical site.