Biotechnology Jobs

• London
• Hybrid · 3 days in office
• Senior

Contribute to the design of novel large-molecule therapeutics by applying computational and machine learning methods to predict biologics properties such as affinity, developability and immunogenicity from sequence. Work within an interdisciplinary computational sciences team alongside ML and biologics discovery experts, benchmarking models, analysing lab data and shaping data-generation strategies for active learning.

AlphaFold

• London
• Hybrid · 3 days in office
• Senior

Lead pharmacology and translational biology strategy for large molecule therapeutics, designing in vivo efficacy and complex in vitro functional assays. Act as Biology Lead on projects, coordinating internal workflows and external CROs, and collaborate with ML and computational biology teams to feed data into generative AI design loops.

AI · ML · Generative AI +1

• Cambridge
• Lead

Lead complex formulation development programmes for biologics, acting as subject matter expert and providing technical oversight across multiple client projects. Design experimental strategies, present findings to clients and external stakeholders, and mentor junior scientists within a multidisciplinary team.

• Macclesfield
• On-site
• Senior
• Permanent

Lead the design, engineering, expression, purification and characterisation of complex biologic therapeutics including monoclonal, bispecific and multispecific antibodies. Acts as biologics scientific lead on client-facing drug discovery programmes, mentoring junior scientists and shaping project strategy within a multidisciplinary Protein Sciences team.

Structural Modelling · AI-enabled Protein Engineering

• Cambridge
• Senior
• Temporary

Hands-on upstream process development role delivering mammalian cell culture studies, including CHO-based fed-batch and perfusion processes, media and feed optimization, and bioreactor operation from ambr systems to bench-scale stirred tanks. Works under minimal supervision within a matrix CMC team, applying DoE and statistical analysis, supporting scale-up and tech transfer to GMP and CMO partners, and providing day-to-day technical coordination to technicians and operators.

ambr · ambr250 · Stirred-Tank Bioreactors +6

• London
• Hybrid · 3 days in office
• Director · manages people

Lead national medical strategy for the Respiratory & Immunology business unit, spanning inhaled therapies and biologics. Define pre-launch and launch medical plans, drive NHS transforming-care initiatives, and oversee MSL and healthcare delivery teams. Provide scientific leadership across regulatory, market access and real-world evidence work.

NHS · NICE · SMC +3

• Slough
• On-site
• Mid-level
• Permanent

Performs routine, non-routine and stability testing of biologic drug substances in a client's Analytical Service Department, running ELISA, cell-based and Biacore assays and capturing data in laboratory software and electronic notebooks. Generates and reviews GMP-compliant documentation, SOPs and protocols, supports method development and validation, and handles out-of-specification investigations while liaising with internal and external clients.

Biacore · Vi-Cell · Microsoft Office

• Stevenage
• Hybrid
• £119,250 – £198,750 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late pre-candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work across small molecules, biologics and antibody drug conjugates, applying AI/ML and quantitative systems pharmacology methods. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

NONMEM · R

• Waltham, United States
• Hybrid
• £188,100 – £313,500 pa
• Director

Leads model-informed drug development for oncology programs, defining and executing model-based strategies from late discovery through lifecycle management. Conducts population PK, exposure-response, simulation-based trial design and dose selection, applying AI/ML, quantitative systems pharmacology and model-based meta-analysis. Presents to governance boards and regulators and works across matrix teams on small molecules, biologics and antibody drug conjugates.

NONMEM · R

• London
• On-site
• Director
• Permanent

Leads CMC regulatory strategy for global submissions including IND, CTA, BLA and MAA, and oversees agency correspondence and compliance for mRNA products. Reviews submissions for readiness, drives health authority interactions, and advises manufacturing and quality teams on change controls and regulatory guidance across vaccines, oncology and rare disease programmes.

IND · CTA · BLA +1

• Oxford
• Hybrid · 3–4 days in office
• Lead
• Permanent

Provides scientific and hands-on leadership for immunogenicity and ligand binding assay bioanalysis supporting mRNA-LNP therapeutic programs, spanning assay development, validation, clinical sample testing and regulatory submissions. Ensures GcLP compliance and partners with cross-functional teams, with opportunities to work alongside data and AI-enabled analytical approaches.

ECL · Gyrolabs · Reporter Gene Assays +3

• London
• On-site
• Entry level
• Internship

A 12-month industrial placement supporting in vivo pharmacology research within Pfizer's Internal Medicine Innovation Centre. Day-to-day work includes rodent husbandry and welfare, non-surgical procedures under a Home Office licence, ELISAs and in vitro potency assays for biologics, all under an experienced Research Director. Distinct for its strong focus on animal welfare and the 3Rs.

ELISA

• London
• On-site
• Entry level
• Internship

A 12-month industrial placement in Pfizer's Peptide Drug Product Development group, working alongside formulation scientists and analytical chemists. The role involves preparing and evaluating peptide formulations, running solubility and stability studies, and gaining hands-on experience with HPLC/UPLC and biophysical characterisation methods.

HPLC · UPLC

• London
• Hybrid
• Senior

Oversees quality control testing for a genetically edited cell therapy, acting as lead point of contact for external CDMOs and QC labs on GMP release, stability and method lifecycle work. Leads OOS/OOT investigations, reference standards and assay controls programmes, authoring and approving SOPs, COAs and protocols. Hybrid role based in London requiring close collaboration with contract test labs and management on compliance risks.

LIMS

• Wrexham
• Hybrid
• Lead
• Permanent

Leads Cell Line Development and Upstream Process Development strategies for biologic products, from candidate selection through commercial manufacturing. Acts as subject matter expert within cross-functional CMC teams, managing CDMO partnerships, supporting regulatory submissions and technology transfer, and mentoring junior scientists.

CHO