Walker Cole International are currently supporting the hire of an Upstream Fermentation Scientist for a leading biologics process development organisation supporting global pharmaceutical and biotechnology companies.
As an Upstream Fermentation Scientist, you will support the development, optimisation, scale-up, and technology transfer of microbial fermentation processes across a range of innovative biopharmaceutical programmes.
Key Responsibilities
• Develop, optimise, and scale microbial fermentation processes using bacterial, yeast, and fungal expression systems
• Design and execute fermentation studies, including media optimisation, process characterisation, growth parameter optimisation, and yield improvement activities
• Support scale-up activities from laboratory through to pilot-scale bioreactors and establish representative scale-down models
• Utilise Design of Experiments (DoE), statistical analysis, and process data to drive process understanding and optimisation
• Support technology transfer activities and ensure successful implementation of processes across development and manufacturing environments
• Collaborate closely with downstream processing, analytical development, strain engineering, and manufacturing teams to deliver integrated bioprocess solutions
• Troubleshoot process challenges and identify opportunities to improve process robustness, productivity, and scalability
• Provide technical leadership within project teams and support the development of junior scientists where appropriate
Knowledge, Skills & Experience
• MSc or PhD in Biotechnology, Microbiology, Biochemical Engineering, Bioprocess Engineering, Bioengineering, Biochemistry, or a related scientific discipline
• Significant industrial or academic experience in microbial fermentation, upstream process development, or industrial biotechnology
• Hands-on experience operating bioreactors across laboratory, bench, and pilot scales
• Strong understanding of batch, fed-batch, and continuous fermentation processes
• Experience with fermentation process optimisation, media development, scale-up, and process troubleshooting
• Knowledge of bioprocess data analysis, DoE, statistical modelling, and process characterisation techniques
• Experience supporting technology transfer, process development, or manufacturing activities would be advantageous
• Strong communication, problem-solving, and stakeholder management skills
This opportunity would suit an Upstream Fermentation Scientist, Fermentation Scientist, Upstream Process Development Scientist, Bioprocess Scientist, Microbial Fermentation Scientist, or Bioprocess Development Scientist looking to further their career within biologics process development.
For further information, please apply directly or contact Mollie Richmond at Walker Cole International for a confidential discussion.
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