Downstream/Purification Senior Scientist

Walker Cole International are currently supporting the hire of DSP Scientists and Senior DSP Scientists for an award-winning bioprocess organisation supporting some of the world's leading pharmaceutical and biotechnology organisations.

As a DSP Scientist, you will support the development, optimisation, scale-up, and technology transfer of downstream bioprocesses across a range of innovative biologics and advanced therapy programmes.

Key Responsibilities

• Develop and optimise downstream purification processes using chromatography, filtration, and other separation technologies

• Design and execute process development studies to improve yield, purity, robustness, and scalability

• Support process scale-up and technology transfer activities from laboratory through to manufacturing environments

• Utilise Design of Experiments (DoE) and data-driven approaches to support process understanding and optimisation

• Analyse and interpret experimental data, preparing technical reports and presenting findings to internal and external stakeholders

• Collaborate closely with upstream process development, analytical development, manufacturing, and client teams to deliver project objectives

• Troubleshoot downstream processing challenges and identify opportunities for continuous improvement

• Support multiple client projects, contributing to project planning, delivery, and technical decision-making

Knowledge, Skills & Experience

• MSc or PhD in Biotechnology, Biochemistry, Biochemical Engineering, Bioengineering, or a related scientific discipline

• Industrial or academic experience in downstream process development, protein purification, biologics development, or bioprocess development

• Hands-on experience with chromatography platforms, including AKTA systems, and filtration technologies such as TFF

• Experience developing purification processes for proteins, antibodies, recombinant proteins, vaccines, viral vectors, or other biologic products would be advantageous

• Understanding of downstream unit operations, process characterisation, and process scale-up principles

• Experience using DoE, statistical analysis, and data-driven process development approaches

• Knowledge of technology transfer, manufacturing support, or GMP environments would be beneficial

• Strong communication, problem-solving, and stakeholder management skills

This opportunity would suit a DSP Scientist, Senior DSP Scientist, Downstream Process Development Scientist, Purification Scientist, Protein Purification Scientist, Bioprocess Scientist, or Downstream Processing Scientist looking to further their career within biologics process development.

For further information, please apply directly or contact Mollie Richmond at Walker Cole International for a confidential discussion.