Latest AstraZeneca Jobs

Associate Director, Safety Epidemiology – Global Patient Safety

Lead the design and execution of post-authorisation safety studies using real-world data to assess and communicate the safety profiles of AstraZeneca’s medicines. Provide strategic epidemiological input to regulatory submissions, safety signal evaluations, and diversity initiatives, collaborating with internal teams and external partners. Drive methodological excellence in pharmacoepidemiology and contribute to global patient safety decision-making across a broad product portfolio.

AstraZeneca Chatham, ME4 4NP, United Kingdom

On-site Permanent

Biologics Account Manager

This role involves driving clinical demand for respiratory biologics by building strategic relationships with healthcare professionals and multi-disciplinary teams across a defined UK territory. The Account Manager will lead formulary access, support homecare utilization, and collaborate with cross-functional teams to implement account plans in complex secondary care environments. Success requires strong commercial acumen, stakeholder influence, and deep understanding of the NHS commissioning landscape.

AstraZeneca Sheffield, United Kingdom

On-site Permanent

Executive Regulatory Science Director, Respiratory & Immunology

This role leads global regulatory strategy for respiratory and immunology therapies across all development stages, from early research to post-marketing. The director will mentor regulatory leads, shape policy, and engage with health authorities like the FDA and EMA to secure rapid approvals with competitive labelling. They will influence key governance decisions and integrate emerging science into regulatory planning.

AstraZeneca Cambridge, United Kingdom

Senior Applied AI & ML Engineer - Evinova

This role involves designing and building applied AI and machine learning systems to transform clinical trial design, using GenAI, agentic systems, and multi-source data integration. The engineer will work on production-grade solutions that improve trial success rates, reduce development time, and lower costs, with a strong emphasis on scientific rigour and real-world impact. The position requires blending deep technical expertise in ML and software engineering with domain knowledge in drug development and regulated environments.

AstraZeneca London, United Kingdom

Pathology Director

Leads medical and technical oversight of an accredited diagnostic laboratory supporting clinical trials and biomarker development. Provides expert interpretation of pathology and biomarker data, ensures regulatory compliance, and drives innovation in digital pathology and companion diagnostics. Works cross-functionally to integrate advanced diagnostic methods into drug development programs.

AstraZeneca Cambridge, United Kingdom

Senior Scientist Biomarker Lead

This role involves designing and delivering biomarker strategies and assays to support clinical development in respiratory and immunologic diseases. The scientist will lead biomarker studies using human biospecimens, interpret complex datasets, and provide evidence-based recommendations to guide trial design and patient selection. Working at the interface of lab science and clinical development, the role emphasizes assay development, cross-functional collaboration, and the application of advanced translational technologies.

AstraZeneca Cambridge, United Kingdom

Director, Generative AI – Chemical Development

Leads the strategy and implementation of Generative AI and agentic workflows in chemical development to accelerate CMC processes and scientific decision-making. Drives adoption of AI in regulated environments, focusing on use cases like knowledge mining, report generation, and experiment planning. Works across scientific, compliance, and digital teams to embed responsible, scalable AI into routine workflows.

AstraZeneca Macclesfield, United Kingdom

Senior Scientist – Diagnostic Deployment

This role involves hands-on development, optimisation, and validation of tissue-based diagnostic assays, primarily using histology and immunohistochemistry (IHC), to support AstraZeneca's clinical trials. The scientist will integrate digital and computational pathology tools, ensure compliance with regulatory standards like CAP/CLIA and ISO, and enhance laboratory workflows through LIMS integration. The position emphasizes scientific rigour, cross-functional collaboration, and innovation in oncology diagnostics.

AstraZeneca Cambridge, United Kingdom

Senior Director, Alliance and Integration Management

Leads integration and alliance management for high-priority pharmaceutical acquisitions, divestitures, and strategic partnerships. Drives cross-functional alignment across legal, finance, clinical, and commercial functions to ensure successful post-deal execution and value delivery. Develops industry-leading processes and represents the company as a thought leader in alliance management.

AstraZeneca Cambridge, United Kingdom

Senior Medical Director Early Clinical Respiratory

This role involves leading early-phase clinical development in respiratory therapeutics, designing and overseeing Phase 1 and 2a trials, and translating scientific innovation into clinical proof-of-concept. The individual will act as a medical expert, shaping clinical strategies, guiding regulatory interactions, and mentoring teams within a global, collaborative environment. Emphasis is placed on biomarker use, translational research, and engagement with external scientific leaders.

AstraZeneca Cambridge, United Kingdom

Senior Quality Associate – Accredited Diagnostic Development Laboratory

This role involves leading quality management within AstraZeneca’s accredited internal diagnostic laboratory, ensuring compliance with CAP/CLIA, IVDR, and ISO standards during the development and validation of precision diagnostic assays. The Senior Quality Associate will drive change control, investigation of non-conformances, CAPA management, and audit readiness, while collaborating closely with lab scientists and regulatory teams. The position plays a key role in enabling biomarker-driven clinical trials through robust, patient-ready diagnostic solutions.

AstraZeneca Cambridge, United Kingdom

Senior Finance Business Partner - Alexion

This role involves leading financial strategy and business partnering for a designated disease area across the UK and Ireland, with full P&L responsibility. The Senior Finance Business Partner will drive forecasting, performance management, and financial governance, using AI and advanced analytics to inform decisions on pricing, reimbursement, and market access. Close collaboration with cross-functional teams ensures strategic alignment and effective delivery of patient-focused therapies.

AstraZeneca London, United Kingdom

On-site Permanent

Executive Regulatory Science Director, Respiratory & Immunology

Lead global regulatory strategy for respiratory and immunology therapies across development stages, from early research to commercialization. Provide expert guidance on regulatory pathways, engage with health authorities, and mentor regulatory leaders. Shape policy and ensure compliance while advancing innovative treatments through key milestones and approvals.

AstraZeneca

Translational Science Lead

Leads end-to-end translational strategies for respiratory disease programmes, integrating human biology, multi-omics data, and biomarker development to de-risk clinical decisions. Designs and implements target validation, patient stratification, and precision medicine approaches while collaborating across discovery, clinical, and data science teams. Drives biomarker strategy into clinical protocols and regulatory submissions, using AI/ML and innovative assays to generate actionable insights.

AstraZeneca Cambridge, United Kingdom

Regulatory Affairs Intelligence Director

This role focuses on transforming regulatory intelligence into strategic decisions that accelerate drug development and approvals. The individual will analyze global regulatory trends, guidance, and precedents to inform pipeline strategy and influence policy, working closely with cross-functional teams and senior leaders. Key responsibilities include conducting in-depth research, providing impact assessments, and integrating emerging technologies like AI into regulatory intelligence processes.

AstraZeneca Cambridge, United Kingdom

On-site Permanent