Senior Scientist

A leading, research-driven biopharmaceutical organisation is seeking an experienced Senior Scientist – In-Vivo Pharmacology to join its Immunology Discovery team.

This is an exciting opportunity to contribute to the discovery and early development of innovative small molecules and biologics targeting immune-mediated inflammatory diseases. The role is hands-on and delivery-focused, playing a critical part in generating high-quality in vivo data to support key project decisions.

Responsibilities:

As a Senior Scientist within the In Vivo Pharmacology group, you will:

• Design, plan, and execute in vivo studies to support target identification, validation, and translational pharmacology.
  
  
• Apply strong expertise in immunology models, ensuring robust experimental design and scientific rigor.
  
  
• Generate, analyse, and interpret complex in vivo datasets to drive project progression.
  
  
• Support the establishment, optimisation, and validation of in vivo models.
  
  
• Oversee outsourced studies with CRO partners where required.
  
  
• Contribute to cross-functional project teams, providing scientific insight to inform decision-making.
  
  
• Ensure full compliance with regulatory, ethical, and animal welfare standards.
  
  
• Maintain clear documentation and contribute to reports, study summaries, and presentations.
  
  You will work closely with internal project teams, matrix functions, and external collaborators in a highly collaborative research environment.
  
  The ideal candidate will have:
  
  
• A PhD (or equivalent) in Pharmacology, Immunology, or a related discipline.
  
  
• Postdoctoral or industry experience within drug discovery.
  
  
• Strong hands-on expertise in in vivo pharmacology, particularly within immunology and inflammatory disease models.
  
  
• Demonstrated ability to design rigorous in vivo experiments and interpret complex biological data.
  
  
• Experience with in vivo cell depletion models (desirable).
  
  
• A Home Office Project Licence (or eligibility to obtain one).
  
  
• A pragmatic, delivery-focused approach with high attention to data quality and scientific standards.
  
  
• The ability to work independently while contributing effectively within a collaborative team.
  
  Keywords: In-vivo, Pharmacology, Models, Immunology, Pharmacology, inflammatory, immune, Home office licence, PIL, Target identification, validation, translational pharmacology, Slough, Windlesham, London, Oxford, Cabridge, Reading, VRS9359DT