The Senior Development Scientist role is a 3-year Knowledge Transfer Partnership (KTP) Associateship funded by Innovate UK and awarded to Imperial College London. The successful applicant will be employed by Imperial and based full time at Orthox Ltd, a small University spin-out Company near Oxford. They will work with academic supervisors at Imperial and industrial supervisors at Orthox to translate and optimise Bouncy Bioglass implants towards clinical applications from technology developed in the group of Professor Julian Jones at Imperial.
Objectives are to:
Transfer materials and manufacturing know-how to Orthox. Implement process controls. Finalise implant design for an osteochondral repair product concept considered to be the largest market opportunity, worth an estimated $2bn annually.
The role involves learning the Bouncy Bioglass manufacture processes at Imperial, including preparation of raw materials, ink manufacture, and 3D scaffold printing and training Orthox staff in these. With Orthox, they will also install and validate equipment, and develop process controls and GMP compliant manufacture, enabling optimisation of prototype medical devices for mechanical, chemical and biocompatibility testing.
Research Duties:
To interact with Prof. Julian Jones as formal academic supervisor and other research staff and students working in broad areas of relevance to the project. To be based full time at Orthox, with regular visits to Imperial and collaborators To interact with Dr Nick Skaer and Dr Robert Walker as formal supervisors at Orthox. To build project management activity To pursue personal development through training provided by the Innovate UK funds and KTP framework. To write progress reports and prepare results for publication and dissemination via journals, presentations and the web. To attend progress and management meetings as required. To perform other reasonable tasks related to the furtherance of the project aims. To provide general assistance from time to time with other research related activities. Carry out sol-gel synthesis of inorganic/organic hybrid inks for direct ink writing. Developing the printing method with a printer at Orthox Characterisation of materials Develop GMP manufacturing capabilities through equipment/process validation, development of process controls and development of GMP compliant manufacturing procedures (. SOPs) To build regulatory understanding and contribute to the development of regulatory documentation relating to the technology/product development. Work well within a dynamic group of students and research associates.
Degree in Materials Science, Chemistry, Biomedical Engineering, Biochemistry, or a similar relevant subject.A PhD (or equivalent) involving research in Materials Science, Organic/Synthetic Chemistry, Biomedical Engineering, Biochemistry or a similar a relevant field of research.A level (or equivalent) in ChemistryWorking in a lab-based research environmentProven record of conducting independent research within a lab-based role including designing and carrying out experiments, analysing results and writing these up for presentation to a wider audienceWorking with inorganic/organic hybrid materialsA sound understanding of organic and inorganic chemistry.Working with controlled/hazardous substancesWorking within a highly regulated/controlled industry . medical/pharmaResearch and/or manufacture using direct ink writing.Presenting results at national/international conferencesCAD design
The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity.Grow your career: Gain access to Imperial’s sector-leading as well as opportunities for promotion and progression Sector-leading salary and remuneration package (including 39 days off a year and generous pension schemes).We provide a wide-ranging benefits package that includes resources, tools and networks to promote a positive working environment.Pensions – excellent employer contributionsSeason Ticket loan – interest free.Childcare facilities – Early Years Education CentreChildcare vouchers – salary sacrifice scheme.Staff accommodationOur flagship sports centre and gym in South Kensington Campus
