Senior Bioinformatician - OxfordImmunocore (NASDAQ:IMCR) is a pioneering, commercial-stage T cell receptorbiotechnology company whose purpose is to develop and commercializea new generation of transformative medicines which address unmetpatient needs in oncology, infectious diseases and autoimmunedisease. Our leaders in R&D are internationally recognised assome of the biotech industry/'s most successful drug developers. Weare creating not just an environment where great minds can interactbut an innovation powerhouse answering the big questions. Focusedon delivering first-in-class biological therapies to patients, wehave developed a highly innovative soluble TCR platform. Our ImmTAXmolecules underpin a new generation of precision engineered drugsthat harness the immune system to treat a broad spectrum ofdiseases with high unmet medical need, including oncology,infectious diseases and autoimmune diseases. At Immunocore, werecognize that our employees are our greatest asset. We value theunique contributions each person brings to our team. By embracingScience, Trust, Respect, Integrity, Diversity, and Entrepreneurship(STRIDE), we create an environment where collaboration thrives,ideas flourish, and transformative changes happen. STRIDErepresents more than just letters; it embodies our shared identityand drives our mission. We are dedicated to developing breakthroughtherapies that transform patients/' lives, advancing medicine, andsupporting one another in these pursuits. Immunocore is proud to bean equal opportunity employer. As such, we are committed tofostering an inclusive workplace where everyone feels valued,respected, and empowered. We encourage applications fromindividuals of all backgrounds, regardless of race, color,religion, sex, sexual orientation, gender identity or expression,pregnancy, age, national origin, disability status, or any othercharacteristic protected by law.To provide focused bioinformaticsexpertise to support the analysis and data management oftranslational biomarker data. This individual will be expected tothoroughly explore publicly available data together with emergingdata from Immunocore/'s clinical trials to provide new insightsinto mechanism of action, molecular heterogeneity of disease andnovel targetsKEY RESPONSIBILITIES* Conduct the analysis oftranscriptomic and genomic sequencing data from our clinical trials* Compliment and develop our scientific hypotheses through themining of public data and the design and analysis of our ownin-house experiments* Develop custom-made tools and analytics toassist interpretation and data visualisation * To contribute toabstracts and manuscripts as required * Maintaining and increasingtechnical knowledge in relevant fields through self-study,observation, attending relevant conferences and training courses.Maintaining accurate records of all work by completingdocumentation on time, following Company procedures * Operating inaccordance with the Company/'s Health and Safety policies.SPECIFICRESPONSIBILITIES * Data analysis: independently testing and,increasingly, leading lines of investigation. Proposing newanalyses based on emerging data and other related information.Providing support on technical aspects to others. * Priorities:establishing priorities for own work and team-based projects;making decisions on prioritisation based on the overall goals ofthe team, department and project, using direct evidence andpersonal experience as guidance. * Technical Knowledge: sharingknowledge with the wider team and, across departments representingthe department both internally and externally. May also act as amentor or manager to other colleagues, especially new hires,sharing scientific and company knowledge. Increasingly providinganalysis of new techniques and theories from outside the Company toadvance the way the company works; sharing these with leadersacross the Company. * Record keeping: ensuring that all records andinformation are up to date, on time and recorded to the correctstandard. Supporting and encouraging others to achieve this.Equipment: providing technical guidance to others within the teamon how to use equipment most effectively; making recommendationsregarding acquisition of new pieces of equipment.Health &Safety: championing and helping others to understand H&S withinthe company, providing ad-hoc training as required.Reporting:communicating and presenting research findings at meetings withcolleagues, senior management and partners.PERSONSPECIFICATIONEXPERIENCE AND KNOWLEDGEEssential* Will be proficientin R/BioConductor, Linux OS and shell scripting bash. Provenprogramming ability (Knowledge of at least one language, preferablyPython). * Understanding of molecular biology, cell biology,immunology or related discipline.* Significant experience ofindependent research in academic or industrial setting, ortransferable skills gained from professional experience* Proposedand driven changes in working practices that have improvedefficiency, supported teams through adoption and change.* Presenteddetailed scientific findings and papers to internal and externalaudiences* Recorded results in a concise and timely way, and incompliance with agreed standards* Experience of building nextgeneration sequencing (NGS) analytical pipelinesDesirable * Led aproject small team, formally or informally, including projectmanagement* May have experience of developing databases, using SQLor similar, and pairing with a user-friendly interface* Mentoredand coached less experienced colleagues in scientific practices andtheory. * May have knowledge of machine learning, appliedstatistics or related fieldEDUCATION & QUALIFICATIONS* PhD in ascientific discipline with a minimum of 2-5 years of relevantexperience (post-doctoral experience may be included) - preferred.*MSc degree or BSc degree with equivalent research or industrialexperience specific to the role - required.
