Bioinformatician / Senior Bioinformatician

Tagomics
Cambridge
4 days ago
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Full time, 2 year contract, hybrid (1 day a week in the office)


About Tagomics:

Tagomics has developed a ground-breaking multiomic biomarker discovery platform that offers a step change in genomics-based disease profiling and diagnosis.

 

Originating from the pivotal research of Dr. Robert Neely and his team at the University of Birmingham, Tagomics' proprietary technology unlocks DNA-based disease-associated biomarkers spanning genetic, epigenetic, and fragmentomic features. In combination with advanced bioinformatic and machine learning approaches we can provide unique biological insights, and we already have exciting results from a range of cancer patient samples including blood and tissue.


Learn more about our technology from our recent scientific paper - http://tinyurl.com/TagomicsPaper


As we gear up for the next phase of our journey, having secured £6.7m in investment to further develop our platform, we have moved to new labs and offices at Illumina Ventures Lab at Granta Park Research Campus near Cambridge as we work towards unveiling our first commercial product.


Learn more about Tagomics and its investors here - http://tinyurl.com/Tagomics


Tagomics invites a Bioinformatician to join our multidisciplinary team to make a lasting contribution to a unique technology that will transform our understanding of disease and diagnosis.


About the role:

We are looking for a bioinformatician to contribute to the analysis and interpretation of NGS data, generated using our unique epigenetics platform, as well as to develop ways to create patient epigenetic profiles and discover novel biomarkers for both diagnostics and prognostics. You will gain exposure to cutting edge computational epigenetics and machine learning approaches and explore the latest bioinformatic developments for biomarker discovery, NGS and epigenetic data analysis. We encourage applicants that don’t meet all requirements or those that have had non-traditional career paths to apply, as diversity builds better teams. We will provide you with support to help you do your best work and make an impact.


Your background will include:

  • A Ph.D. in bioinformatics and/or epigenetics
  • Experience in handling and processing NGS datasets (such as WGS, Exome sequencing, RNA-seq etc), including raw data quality control, alignment and processing as well as analysis and interpretation
  • Familiarity with data visualization and analytics tools
  • Comfortable coding in either Python or R


It would be great if you had:

  • Knowledge of analysing epigenetics datasets such as ATAC-seq ChIP-seq, WGBS, MeDIPs, etc
  • Experience in analysing ‘omics datasets for biological interpretation and actionable insights. 
  • Scientific domain expertise in epigenetics, cancer genomics, liquid biopsy or biomarker discovery and relevant publications in peer-reviewed journals
  • Familiarity with cloud environments and bioinformatics pipelines (e.g. Nextflow)
  • Familiarity with machine learning algorithms
  • Familiarity with variant calling packages and/or gene panels


We are a small but rapidly expanding company – by joining us early in our journey you will gain exposure to the various facets of start-up life and have a unique chance to contribute to our technology and influence our company culture. As we expand this role has excellent personal development opportunities.  


The role is hybrid (minimum 1 day a week in the office at Granta Park, Cambridge). We offer:

  • Competitive salary
  • Matched pension contributions up to 8%
  • Private healthcare
  • Performance related bonus scheme 


We offer flexible working and believe in maintaining a sustainable work-life balance. Our modern offices at Granta park are lift accessible and have ample on-site parking as well as bike stands. The campus has a shuttle bus that runs to Cambridge and Whittlesford train stations, an onsite nursery, gym, restaurant and coffee shop. 


We are not currently sponsoring visas for this position. You will need to be able to legally work in the UK. 


No agencies please- we will not be accepting speculative CV's for this opening. 

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