Research Scientist - Protein Analysis

Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and a commercial presence in many global locations across the US, APAC and Europe.

Oxford Nanopore employs from multiple subject areas including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market.

Oxford Nanopore’s sequencing platform is the only technology that offers real-time analysis, in fully scalable formats from pocket to population scale, that can analyse native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths. Our goal is to enable the analysis of any living thing, by anyone, anywhere!

We are looking for a highly motivated individual to join the Research Team as a Protein Analyst with a focus on mass spectrometry to provide high-quality, timely and accurate analyses of protein, peptide and other samples as provided, with a view to advising the direction of research projects and driving them forward.

The Details...

This role will principally be laboratory-based to begin with, and analyses will be split approximately 50:50 between mass spectrometry and other analyses. The role expects significant collaboration with other teams and projects, with the central aim of accelerating research and development of Oxford Nanopore products.

The successful candidate will have good laboratory skills, reliability in bench-based practical work, and the ability to carry out sophisticated and routine tasks with equal attention to detail and thoroughness.

Applications are encouraged from candidates who can adapt quickly to new challenges and enjoy working with an agile approach to research. The successful candidate will need to work meticulously to a high standard and be able to perform well under pressure to meet deadlines in a demanding and fast-paced environment.

What We're Looking For...

A PhD or equivalent experience in a relevant subject. Experience working with ESI mass spectrometry equipment. Experience with protein sample preparation methods including solid phase extraction, HPLC, buffer exchange methods. The ability to use mass spectrometry software for the analysis of protein digest samples, including proteomics and modification mapping, and to run pre-existing LC-MS methods. Experience preparing mass spectrometry compatible samples.

Desirable experience includes:

Previous experience with Waters Q-ToF instruments including preventative and reactive maintenance Experience in software requirements for Q-Tof instruments, specifically Waters instruments. Experience with oligonucleotide (DNA and RNA) sample preparation methods. Experience with small molecule mass spectrometry. The ability to develop new LC separation methods over a range of chemistries. The ability to develop new mass spectrometry methods for the analysis of proteins, peptides and small molecules.

We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary. Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment.

If you are looking to utilise your skills to really make a difference to humankind, then consider joining our team and apply today!