Engineer the Quantum RevolutionYour expertise can help us shape the future of quantum computing at Oxford Ionics.

View Open Roles

Research Scientist - Method Development

Charles River
East Lothian
2 weeks ago
Create job alert

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary


The Chromatographic Bioanalysis department is a large team located at our site in Tranent, East Lothian. We are looking for a Research Scientist to join the method development team within the department, to participate in the development of quantitative assays on our fleet of over 20 high spec LC MS instruments.

As a CRO we have the opportunity to work with a large variety of analytes, from small polar molecules to peptides, proteins, nanoparticles and oligonucleotides. This broad range of analytes and our involvement in a large variety of programme designs, from early-stage pre-clinical investigative work to in-vitro biosimilar evaluation and clinical trials, means that we are always expanding our knowledge and skills. As well as our ever-evolving workflow, our consistent involvement with the industry through conferences, literature, and multi-company project teams, provide additional opportunities for development of both the industry and individuals. 

In this role you will act as a scientific expert, as well as planning and organizing for the efficient development of bioanalytical methods. This will involve using a variety of analytical techniques, or undertaking original research to develop new techniques, to establish methods suitable for generating data in a regulatory environment in a timely and cost-effective manner. 

In more detail the role will include:

Responsibility for the development of LC conditions, optimizing MS/MS parameters and refining extraction procedures for the quantitative analysis of analytes from biological matrices. Including responsibility for decision making based on the data generated.


Routinely communicating effectively with internal and external stakeholders regarding study organization, progress, and challenges.
Leading complex troubleshooting, both during method development studies and in collaboration with other teams during later stages of an assay's usage
Contribution to the generation of scientific papers and presentations
Proactively mentoring junior method development scientists, to promote talent development.
Demonstrating innovation through development of alternative scientific approaches and improvement of existing processes. 

Job Qualifications


Applicants should have:

A minimum of a BSc or equivalent in a scientific analytical related discipline.


Familiarity with the use of standard laboratory equipment and analytical instrumentation.
Experience developing assays in an analytical laboratory, preferably in a bioanalytical department.
An understanding of appropriate regulatory guidance in bioanalytical method validation in addition to current GLP/GCP regulations
Excellent communication (verbal and written), presentation and interpersonal skills.
Effective decision-making skills and the ability to work independently in a fast-paced environment. 
A proven level of problem-solving ability and adaptability, in relation to both scientific and project management challenges.
Experience supervising and developing junior colleagues.
A proven ability to identify, design and conduct research projects based on analysis of industry trends.


Additionally, familiarity with protein analysis and HRMS workflows would be highly beneficial for the role.

Closing date for applications is Monday 1st September COB 

The annual salary for this role is : £40, 470.57

About Safety Assessment

Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.

At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.

Related Jobs

View all jobs

Research Scientist (Surface Science)

Research Scientist - Method Development

Research Scientist - Active Materials

Research Scientist - Oligonucleotide Synthesis

Research Scientist in Marine Ecology and Machine Learning

Research Scientist - Method Development

Subscribe to Future Tech Insights for the latest jobs & insights, direct to your inbox.

By subscribing, you agree to our privacy policy and terms of service.

Industry Insights

Discover insightful articles, industry insights, expert tips, and curated resources.

Seasonal Hiring Peaks for Biotechnology Jobs: The Best Months to Apply & Why

The UK's biotechnology sector has evolved into one of Europe's most dynamic and lucrative career markets, with roles spanning from laboratory research to regulatory affairs and bioprocessing engineering. With biotech positions commanding salaries ranging from £28,000 for entry-level research associates to £95,000+ for senior directors, understanding when companies actively recruit can significantly enhance your job search success. Unlike traditional industries, biotechnology hiring follows distinct seasonal patterns driven by research funding cycles, regulatory submission deadlines, and academic collaboration timelines. The sector's unique blend of scientific rigour, commercial pressure, and regulatory oversight creates predictable hiring windows that savvy professionals can leverage to advance their careers. This comprehensive guide explores the optimal timing for biotechnology job applications in the UK, examining how funding announcements, clinical trial phases, and academic calendars influence when companies expand their teams and why strategic timing can make the difference between landing your ideal role and missing the opportunity entirely.

Pre-Employment Checks for Biotechnology Jobs: DBS, References & Right-to-Work and more Explained

The biotechnology sector in the UK continues to flourish as one of the world's leading life sciences hubs, with companies ranging from cutting-edge gene therapy startups to established pharmaceutical giants seeking talented professionals. However, securing a position in this highly regulated and security-conscious industry involves comprehensive pre-employment screening that goes far beyond typical recruitment processes. Whether you're a research scientist, bioprocess engineer, regulatory affairs specialist, or clinical trial manager, understanding the extensive vetting requirements is essential for successfully navigating your career in biotechnology. This comprehensive guide explores the various background checks and screening processes you'll encounter when applying for biotech positions in the UK, from basic eligibility verification to stringent security and regulatory compliance assessments.

Why Now Is the Perfect Time to Launch Your Career in Biotechnology: The UK's Life Sciences Renaissance

The United Kingdom stands at the precipice of a biotechnology revolution that promises to reshape medicine, agriculture, manufacturing, and environmental sustainability for generations to come. From the gene therapy pioneers in Oxford to the synthetic biology innovators in Cambridge, Britain's biotech sector is experiencing unprecedented growth, creating extraordinary opportunities for career changers and new graduates alike. If you've been contemplating a move into biotechnology, the stars have never been more perfectly aligned. The convergence of scientific breakthroughs, government investment, industry expansion, and societal need has created a career landscape rich with possibility and purpose.