Research Fellow Role in Bioprocessing and Biomanufacture of Cell and Gene Therapies

UCL Eastman Dental Institute
London
3 months ago
Applications closed

Related Jobs

View all jobs

Senior Sales Manager, Life Sciences

Gynaecology Oncology Clinical Fellow (Basé à London)

Postdoctoral Fellow - Hill lab

Research Associate in Super-Resolution Ultrasound Imaging - Strand, London, WC2R 2LS

Locum Consultant Microbiologist - Watford

Clinical Senior Lecturer KCL and Honorary Consultant in PET Imaging - Strand, London, WC2R 2LS

About the role

The primary role of the Research Fellow will be to lead and execute experimental studies focused on the bioprocessing and scalable production of mRNA and lipid nanoparticles (LNPs) for gene therapy applications. This will involve developing and optimising manufacturing processes, investigating critical process parameters, and improving the efficiency, consistency, and quality of mRNA-LNP formulations. Key responsibilities will include the development of scalable protocols for mRNA synthesis and purification, formulation and characterisation of lipid nanoparticles, and the integration of these processes into continuous and large-scale production workflows. The role will also require expertise in bioreactor operations, upstream and downstream processing, and quality control methodologies. The candidate will establish and optimise new assays and experimental protocols to evaluate product stability, encapsulation efficiency, and gene delivery efficacy. Familiarity with current Good Manufacturing Practice (cGMP) standards and regulatory requirements is essential, as is an understanding of the commercial landscape of mRNA-LNP-based therapeutics. In addition to leading their research programme, the Research Fellow will play a central role in managing and supporting projects within the CGTB Group. This includes mentoring doctoral students, collaborating with external industrial and academic partners, and contributing to the development of new initiatives in the field of mRNA and LNP bioprocessing.

About you

To succeed in this role you will have: • A PhD awarded (or about to be) in a relevant subject. This may include biotechnology, biochemical engineering, or molecular biology with relevance to bioprocessing, analytics, and an interest in scalable manufacture of mRNA-lipid nanoparticle (LNP) therapeutics for gene therapy applications. • Experience in mRNA production, LNP formulation, and characterisation for in vivo gene delivery applications. • Training and experience in bioprocess development, including the use of bioreactors for scalable production. • Experience with product characterisation assays, including particle size analysis, encapsulation efficiency, mRNA integrity (, gel electrophoresis), and biological activity assays such as in vitro transfection and gene expression analysis (, qPCR, ELISA).

What we offer

As well as the exciting opportunities this role presents, we also offer some great benefits some of which are below: • 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days)• Additional 5 days’ annual leave purchase scheme• Defined benefit career average revalued earnings pension scheme (CARE)• Cycle to work scheme and season ticket loan• Immigration loan• Relocation scheme for certain posts• On-Site nursery• On-site gym• Enhanced maternity, paternity and adoption pay• Employee assistance programme: Staff Support Service• Discounted medical insurance

Get the latest insights and jobs direct. Sign up for our newsletter.

By subscribing you agree to our privacy policy and terms of service.

Industry Insights

Discover insightful articles, industry insights, expert tips, and curated resources.

Jobs Careers

Biotech Job Interview Warm‑Up: 30 Real R&D & Project‑Design Questions

The biotechnology sector is at the forefront of scientific innovation—encompassing everything from drug discovery and gene editing to agricultural improvements and environmental sustainability. It’s a field that combines cutting-edge research, regulated processes, and commercial acumen. As such, biotech job interviews can be both exciting and rigorous, often spanning technical, operational, and strategic discussions. If you’re gearing up for a biotech interview, be prepared for questions that dive into cell and molecular biology, bioinformatics, clinical trials, manufacturing regulations, and even data analysis. Beyond scientific expertise, recruiters are keen to see how you handle project planning, regulatory compliance, and cross-functional collaboration—especially if the position involves leadership or project management elements. Whether you’re seeking a lab-based R&D role, a regulatory affairs position, or a biotech project management opportunity, thorough preparation is essential. In this article, we’ll explore 30 real interview questions commonly asked in the biotech sector. By reviewing these questions and thinking through your responses, you’ll develop the confidence and clarity you need to showcase your talents effectively. For those looking for the latest biotech opportunities, head to www.biotechnologyjobs.co.uk. It’s a centralised place to discover exciting roles within the UK biotech landscape—covering everything from start-ups to large pharmaceutical companies. Let’s dive in and get you interview-ready.

Jobs

Negotiating Your Biotech Job Offer: Equity, Bonuses & Perks Explained

How to Secure a Compensation Package That Reflects Your True Value in the UK’s Thriving Life Sciences Sector Introduction Biotechnology is one of the most dynamic and impactful sectors in today’s global economy—particularly in the UK, which boasts a thriving research ecosystem and a burgeoning community of innovative start-ups. From cutting-edge work on gene editing and CAR-T therapy to breakthroughs in diagnostics and personalised medicine, the biotech field promises vast opportunities for mid‑senior professionals to make a meaningful difference. However, with these opportunities comes the need for careful negotiation when evaluating a new role. Biotech companies—whether they’re large pharmaceutical giants or lean start-ups—often structure compensation packages that go far beyond simple salaries. These may include equity grants, performance-based bonuses, and a range of perks designed to attract top talent in a competitive market. Focusing solely on your base salary could mean missing out on substantial long-term rewards or lifestyle benefits. In biotech, your contributions might directly influence life-changing products, high-stakes clinical trials, or novel therapeutic approaches. Hence, your compensation should reflect both the immediate and future value you bring. This article aims to be your comprehensive guide to negotiating a biotech job offer in the UK. We’ll delve into why negotiation goes beyond salary, how equity functions in the biotech context, and how performance bonuses and other perks can amplify the overall value of your compensation. Geared for mid‑senior professionals, this guide offers actionable insights to help you secure a holistic compensation package that aligns with your expertise, future goals, and the impact you will have on advancing life sciences.

Jobs

Biotech Jobs in the Public Sector: Where to Find Meaningful Careers Across the NHS, Research Councils, and Beyond

Biotechnology has become one of the most vibrant and impactful fields of the 21st century, transforming everything from healthcare and pharmaceuticals to agriculture and environmental conservation. In the UK, the public sector is at the forefront of many biotech initiatives, supported by world-class research institutions, government bodies, and large-scale healthcare networks such as the National Health Service (NHS). For professionals seeking purpose-driven work, biotech jobs in the public sector present a compelling opportunity to blend scientific innovation with a meaningful impact on society. Whether you aspire to develop cutting-edge therapies for chronic diseases, optimise food production in a sustainable way, or champion environmental conservation, the public sector’s broad remit means there are numerous pathways to explore. In this article, we’ll delve into the biotech jobs landscape within the UK public sector—shedding light on why biotechnology is crucial for government bodies, which organisations are leading the charge, and the types of roles available. We’ll also discuss the skills needed to excel in these positions, potential salary ranges, and how to successfully apply. By the end, you’ll have a clearer picture of how you can leverage your biotech expertise to serve the nation through a public sector career.

🍪 We use cookies to enhance your browsing experience on our website. By continuing to use this site, you consent to the use of cookies as described in our Cookie Policy. You can review our Cookie Policy for more information.