For informal queries, please email David Roper (Professor) at .
Project Title:SEDS Glycosyltransferases as Antibacterial Targets
We wish to recruit a senior postdoctoral researcher with skill sets in the general area of protein biochemistry, enzyme characterisation, assay design and enzyme inhibition studies.
The goal of this project is to develop novel assays suitable for high-throughput screening, which may include FRET based measurements for the quantitate detection and measurement of enzyme activity in relation to the polymerisation of lipid II into peptidoglycan glycan strands by bacterial SEDS-PBP protein complexes.
This project will require a close working and reporting relationship with a major pharmaceutical company funder in a milestone driven project.
The post demands demonstrable time and project management skills and may involve travelling in Europe to meet with the industrial sponsor and would be suitable for applicants with several years postdoctoral experience.
You will join an ambitious interdisciplinary team on an initial 2-year project in which microscopy, biochemistry, molecular biology and microbiology will be used to study and understand the role of this complex in bacterial cell wall biosynthesis in the context of novel antibacterial treatment development.
The successful applicant will have a strong background in assay development skills, including knowledge and experience of molecular biology and membrane protein purification skill sets that support protein assay discovery and design.
Experience in relation to industry standard parameters and requirements including assay format miniaturization will be required.
The post will be based within the research group ofDavid Roperat the School of Life Sciences, and is available for up to 2 years.
Appointments will be made initially at the FA6 (Sp 36) as Research Fellow or FA7 (Sp 37) as Senior Research Fellow / Assistant Professor (Research Focused) of the published Warwick payscale according to experience and skills of the candidate. We reserve the right to make an offer to applicants as Research Fellow, depending on level of experience demonstrated against the essential or desirable criteria.
The academic title for this post is Assistant Professor (Research Focused), but this is a Research Fellow or Senior Research Fellow level post and does not involve teaching.
About You
We wish to recruit an experienced postdoctoral level researcher with skill sets in the general area of protein biochemistry, enzyme characterisation, assay design and enzyme inhibition studies.
The successful applicant will have a strong background in enzyme assay development skills, including knowledge and experience of molecular biology and membrane protein purification skill sets that support protein assay discovery and design.
Experience in relation to industry standard parameters and requirements including assay format miniaturization will be required.
The post demands demonstrable time and project management skills and may involve travelling in Europe to meet with the industrial sponsor and would be suitable for applicants with several years postdoctoral experience in academic or industrial settings.
How to Apply
CLOSING DATE: Sunday 30 March 2025 at 23:55 (GMT)
To apply, please click ‘Apply’ below and submit an application form by the closing date. Please plan for any potential delays asyou will not be able to submit an application past this deadline(even if you opened the form at, say, 11.30pm).
Please attach a CV and cover letter (max. 2 pages).
- Your CV should include a list of publications.
- Your cover letter should include the reasons for your scientific interest in this project and fit to the essential and desirable criteria.
This information will be used in the shortlisting process and without this evidence we may not be able to shortlist your application.
Please note that if you do not evidence the essential criteria we may not be able to shortlist your application.
To streamline our hiring processes, we can only accept applications via our official website,warwick-careers.tal.net.
Interview Date: TBC
Start Date: By 30 June 2025
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