Research Associate

About Oxford Biotherapeutics

Oxford Biotherapeutics is a clinical-stage biotechnology company specializing in the development of antibody therapeutics for the treatment of cancers. You will play an integral role in the discovery of new antibody-based oncology therapeutics. Our OGAP verify platform is the world's largest, cancer specific, membrane protein library, directly measuring plasma membrane protein expression in patient tumors. OGAP verify is used to identify novel, highly tumor specific antigens for novel first-in-class Antibody Drug Conjugates (ADC), T-cell Engagers (TCE) and Chimeric Antigen Receptor T Cell (CAR-T) therapeutic targets. Our lead asset, OBT076, is an Antibody Drug Conjugate in Phase 1b clinical development. Our clinical and pre-clinical pipeline of novel biologics is balanced between internal programs, focused on ADCs and checkpoint regulators, and externally partnered programs with key innovators in oncology such as Roche and Boehringer Ingelheim.

We are looking for a Research Associate In Silico to join our Oxford-based team as part of the OBT UK Target Discovery Bioinformatics team.

Purpose of the Role

In this role, you will support the discovery, investigation, and presentation of therapeutic cancer targets using bioinformatics-based approaches. Training will be provided as needed.

This position would be ideal for a bioinformatics graduate with an interest in cancer biology and/or mass spectrometry-based proteomics.

Essential Duties and Responsibilities:

• Assist with bioinformatic pipeline including: Researching and annotating proteins of interest from internal and public resources.
• Assist with several routine bioinformatics tasks to support business development, target discovery and US labs.
• Work with the wider bioinformatics team to help Implement ad-hoc tasks for business development, target discovery and US teams where appropriate.
• Creating and developing new and existing bioinformatic tools
• Analysing, summarising and presenting of data
• Assist with any other function areas as needed

Please note the roles and responsibilities for the position include but are not limited to the above.

Knowledge, Experience, and Skills:

• Good knowledge of programming and an interest in developing these skills (e.g. Python, R).
• Masters degree from a computational or biological related course (e.g. biology, bioinformatics, computer science, etc.)
• Experience reading and summarising scientific literature
• Basic knowledge of proteomics and cancer biology beneficial but not essential
• Good written and spoken English
• Familiarity with Microsoft office (Excel, PowerPoint, Word)
• Good knowledge of statistics and an interest in developing these skills

We’re looking for someone who embodies a scientific mindset and is eager to adapt and grow. Key traits that are essential for this role include:

• Methodical thinking
• Strong analytical skills
• High attention to detail
• Enthusiasm for research
• Self-motivation
• Willingness to learn new techniques

One of our top priorities is to maintain the health and wellbeing of our employees and their families. To achieve this goal, we offer comprehensive benefits.

Benefits Offered:

• Private health care (Bupa)
• Health Cash Plan
• Generous pension scheme with potential employer contribution of up to 10% (based on match contributions)
• Discretionary annual bonus scheme
• Free onsite parking
• Office snacks
• Enhanced holiday entitlement above statutory minimum plus public holidays
• Employee Referral Bonus Program
• Annual training budget for professional development
• New hire share options
• Team building events and activities

Pay Range: £26k-£30k per annum.

Equal Opportunities Statement

OBT is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status. All qualified applicants will receive consideration for employment.

Why Join Us- We promote a culture of innovation, responsibility, and commitment to our goals and objectives. Together, we believe, we can pool our resources and our uniqueness to develop novel, robust cures for one of the most challenging health conditions today. We recognize that our team is only as good as the people in it. Our people have used the words friendly, collaborative, and hard working to describe the culture here at OBT. This is why, while we strive to ensure that we hire only the best people. We also strive to provide a working environment that is based on cooperation, innovation, and mutual respect.

#J-18808-Ljbffr