Job description
Site Name:UK - West Sussex - Worthing
Posted Date:Feb 12 2025

Downstream and Scale-up Manager

Closing Date for Applications – 26th February (COB)

This is a site-based role at Worthing, within the Global Manufacturing Science & Technology (MSAT) organisation.

The Global Manufacturing Science and Technology (MSAT) organisation is a network-focused function which provides strategic direction and technical and operational support to ensure that GSK Global Supply Chain network, site goals and objectives are achieved, through a focused strategy execution. 

MSAT is the keeper of the body of knowledge associated with the formulation, device components, analytical testing and manufacturing unit operations, creating the instruction set and ensuring manufacturing operations stay aligned with the registered process. The primary objective is to ensure manufacturing processes are capable, compliant, in control, continuously improved and aligned across Sites. 

MSAT’s primary functions are to lead technology transfers, implement control strategies, provide technical process support, provide process support across the product lifecycle, while implementing new products and new modalities for commercial products and product-related improvement programs within the GSK GSC perimeter. 

In this role you will be responsible for leading a team of scientists and engineers to develop new or second generation fermentation, cell culture and downstream extraction and purification processes for small and large molecule APIs, intermediates and enzymes, with transformative impact including to sustainability.  You will be accountable for the team’s delivery of screening, optimisation, characterisation, validation, scale-up and tech transfer of processes to partners in GSC, R&D, Vaccines or external supply.

We create a place where people can grow, be their best, be safe, and feel welcome, valued, and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpageLife at GSK | GSK

In this role you will:

• Provide professional and scientific leadership to enable fermentation scientists and downstream engineers to deliver on programme objectives to develop, characterize and /or validate processes across multiple scales and platform technologies. Drive development for all individuals in team.
• Promote and monitor technical standards. Identify and champion alternative strategies, ideas and opportunities. Make effective decisions based on interpretation of results across multiple programs. Lead interactions with senior stakeholders ensuring outcomes influence stakeholder decision making.
• Manage team resource and expertise allocation across projects with the ability to prioritise new opportunities.
• Work collaboratively as a key member of the department leadership team.
• Maintain a high level of relevant scientific expertise and visibility; and provide scientific leadership in areas of fermentation, cell culture, extraction and purification, responsible for the technical aspects of bioprocess design and technology transfer.
• Define and drive the highest levels of safety and good lab practice across the department.

Why you?

Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

• Graduate qualification in Chemical or Biochemical Engineering, Biochemistry or equivalent life sciences.
• Strong scientific, supervisory and leadership skills.
• Strong interpersonal and leadership skills. Solid team player able to function within team-based organisation and an ability to interact with peers, team members and senior personnel in a dynamic and multidisciplinary environment.
• Able to prioritise and decide appropriate course of actions. Effective at implementing decisions.
• Knowledge of cGMP and regulatory requirements.

Preferred Qualifications & Skills:

If you have the following characteristics, it would be a plus:

• Previous experience in the pharmaceutical industry and/or process development including supervisory or management experience.

About Worthing Manufacturing Site:

Manufacturing at the Worthing site is for antibiotics. It is advised that you take this into consideration when deciding to apply for this position.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or . The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click thelinkand scroll to the Careers Section where you will find answers to multiple questions we receive.

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it.  Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

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