At Charles River, we are passionate about improving the quality of people’s lives. When you join our global family, you will help create healthier lives for millions of patients and their families.
Charles River employees are innovative thinkers, who are dedicated to continuous learning and improvement. We will empower you with the resources you need to grow and develop in your career.
As a Charles River employee, you will be part of an industry-leading, customer-focused company at the forefront of drug development. Your skills will play a key role in bringing life-saving therapies to market faster through simpler, quicker, and more digitalized processes. Whether you are in lab operations, finance, IT, sales, or another area, when you work at Charles River, you will be the difference every day for patients across the globe.
We are currently recruiting for a Scientist who will be responsible for the planning and execution of projects to support in house and contracted programmes of work performed within the MSAT team. The successful candidate will also be required to support wider processing activities within the MSAT team (upstream, downstream, analytics and molecular biology).
Key duties and responsibilities include but aren't limited to:
• Performing purification of plasmid DNA including Chromatography via AKTA and Tangential Flow Filtration.
• To execute and complete Small-scale pre-production evaluations.
• To assist with Research grade production of plasmid DNA using kits up to giga prep scale.
• To provide technical input into experimental design and troubleshooting.
• To provide In-process analytics (productivity/purity) and data analysis.
• To ensure documentation is generated for protocols, study plans and study reports in a timely manner, and to a high standard as per Charles River policies, as assigned.
• To support with the development/continuous improvement of techniques / processes within the MSAT team and other areas of the business.
Qualifications and Key requirements:
• A degree in Biology, Biotechnology, Biochemistry or equivalent scientific qualification.
• Previous practical laboratory experience in Downstream Processing is essential.
• Previous experience with basic laboratory techniques, including aseptic processing is essential.
• The ability to demonstrate a strong understanding of cGMP manufacturing.
• Able to demonstrate strong written and verbal communication skills.
• The ability to work as part of a team and independently as required.
• Be able to work under the pressure of client and business milestones and needs.
About Corporate Functions
The Corporate Functions provide operational support across Charles River in areas such as Human Resources, Finance, IT, Legal, Sales, Quality Assurance, Marketing, and Corporate Development. They partner with their colleagues across the company to develop and drive strategies and to set global standards. The functions are essential to providing a bridge between strategic vision and operational readiness, to ensure ongoing functional innovation and capability improvement.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.
At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.
For more information, please visit www.criver.com.
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