Clinical Research Fellow

Ref Number B02-08865
Professional Expertise Research and Research Support Department
School of Life & Medical Sciences (B02)
Location: London
Working Pattern: Full time
Salary: See advert text
Contract Type: Fixed-term
Working Type: On site
Available for Secondment: No
Closing Date: 22-Jun-2025
About Us
The main focus of the Department of Neuroinflammation is research into multiple sclerosis (MS), employing a broad range of basic and clinical methods, including clinical therapeutic trials.
The Optimal Clinical Trials Platform for Progressive Multiple Sclerosis (OCTOPUS) is a multi-arm, multi-stage (MAMS) adaptive platform trial designed to accelerate the development of re-purposed or novel treatments aimed at slowing or halting disability progression. The trial is conducted across neuroscience sites in the UK, including the Queen Square MS Centre (QSMSC). Treatments tested will primarily target neuroprotection and remyelination mechanisms.
About The Role
We are seeking a Clinical Research Fellow to work on all clinical aspects of the OCTOPUS project, led by Professor Jeremy Chataway (UCL, Chief Investigator) and Professor Max Parmar (Director, MRC CTU, UCL). You will collaborate closely with Professor Chataway and the UCL MRC CTU team on trial operations. Responsibilities include contributing to the UK-wide recruitment strategy, pre-screening participants via the OCTOPUS expression of interest portal, recruiting and consenting patients at UCLH, conducting clinical assessments, and collaborating on data collection, processing, and interpretation.
You will coordinate blood collection and analysis, participate in broader data analysis activities, and contribute to ongoing and new research projects. There will be opportunities to be involved in both acute and long-term care of people with MS.
You may opt to enroll as a doctoral student and complete a PhD alongside employment. An honorary contract will be sought from UCLH NHS Foundation Trust (and other Trusts where applicable), requiring a DBS check.
The post is available from 01 August 2026, funded by OCTOPUS until 31 December 2028.
For reasonable adjustments or accessible application formats, contact the Institute of Neurology HR Team at

. For informal enquiries, contact Dr. Sean Apap Mangion at



and Dr. Charles Wade at the same email.
A full job description and person specification are available via the provided links.
About You
You will be a registered Medical Practitioner, licensed in the UK, with completed CMT/IMT training and MRCP. You should understand neurological biology and research methodology, with evidence of research experience and clinical supervision capability. Excellent communication, interpersonal, organisational skills, independence, and initiative are essential.
This role qualifies for a skilled worker certificate of sponsorship or a global talent visa under UK Visas and Immigration legislation. UCL welcomes international applications requiring visas.
What we offer
The salary range is £48,580 - £75,038 per annum including London Allowance, dependent on NHS contract/stage of training. Benefits include:
41 days holiday (27 days annual leave, 8 bank holidays, 6 closure days)
Additional 5 days’ annual leave purchase scheme
CARE pension scheme
Cycle to work scheme, season ticket loan
Immigration loan
On-site nursery and gym
Enhanced maternity, paternity, and adoption pay
Employee assistance programme
Discounted medical insurance
More info at

UCL Rewards & Benefits .
This appointment is subject to UCL Terms and Conditions of Service for Research and Professional Services Staff. Details at

UCL HR Conditions .
Our commitment to Equality, Diversity and Inclusion
UCL promotes an inclusive environment, values teamwork, recognises individual strengths, and is committed to advancing careers of all. 12% of staff are involved in EDI initiatives; visit our EDI website for more. UCL holds an Athena SWAN Silver award for gender equality.
We encourage applications from underrepresented groups including Black, Asian, ethnic minorities, disabled people, LGBTQI+, gender-diverse individuals, and women in senior roles.
Available documents include the job description, person specification, and candidate guidance, accessible via download links.

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