Job title:Cell Biologist (Scientist I / Scientist II DOE)
Job type: 2-year fixed term contract
Location:Oxford
Salary:Competitive salary
Right to work:You must have the right to work in the UK
Application deadline:1st November 2024
Application submission:CV and cover lettervia our websitewww.omass.com/working-here/
OMass Therapeutics is a biotechnology company based in Oxford discovering medicines against highly- validated target ecosystems, such as membrane proteins or intracellular complexes. The company’s unique OdyssION™ technology platform comprises novel biochemistry techniques, next-generation native mass spectrometry, and custom chemistry. OMass is advancing a pipeline of small molecule therapeutics in rare diseases and immunological conditions, that target solute carriers, complex-bound proteins, and GPCRs.
We are seeking a Scientist with a background in eitherCell Biology, Immunology or Pharmacology. You will be part of a dynamic andinnovativeenvironment and will become an integral part of our vision to address patients’ unmet needs while building Britain’s Biggest Biotech. You will use your expertise and scientific curiosity to solve drug discovery challenges, as part of multi-disciplinary project teams. You will be able to work in state-of-the-art laboratory and modern facilities for optimumcollaborationalongside afocusedandcaringteam.
You will already possess experience in immunological assays or cellular pharmacology to provide compound profiling support for our ongoing drug discovery projects. We are looking for an enthusiastic team player who can assist in the development and running of in vitro assays to characterise the potency and mechanism of action of novel chemical modulators. To find out more about the meaningful work OMass delivers, as well as our EVP you can find this herehttps://www.omass.com/
Requirements
Essential Experience, Skills and Qualities
· MSc or BSc in Cell Biology/Immunology/Pharmacology (or related discipline).
· Experience working with cell-based or biochemical assays to assess cell biology and/or pharmacology of novel molecules across different protein target classes.
· Ability to independently analyse data from functional and/or binding assays.
· Good working knowledge of different detection methodologies, including fluorescence- and luminescence-based techniques.
· Ability to learn and implement new technologies and protocols.
· Responsible and focused approach to independent and collaborative work, with the ability to prioritise and deliver high quality work to deadlines.
· Innovative and ambitious mindset, with an inquisitive and agile approach to problem-solving and overcoming technical challenges; motivated to continuously learn and take on challenges.
· Excellent communication skills, both written and verbal.
Preferred Experience and Skills
· Experience in pharmaceutical/biotech industry
· Experience in signal transduction, cell biology or immunology
· Experience of automated liquid handling systems.
Role Responsibilities
· Cell-based and biochemical assay development using technologies such as fluorescence and luminescence readouts
· Assessment of compound potency using a variety of biochemical and cellular functional readouts
· Assessment of protein target expression and function at the mRNA and protein level using relevant assay readout systems
· Culture and maintenance of mammalian primary and immortalised cell lines, genetic manipulation of cells including generation of new recombinant cell lines
· Designing and performing studies to elucidate compound mechanism of action
· Presenting study data at project core and team meetings in dedicated project meetings and via email to the wider project team
· Exercising committed compliance to company policies, including reliable and timely recording of data into company databases
· Share information openly and work collaboratively with other departments to help advance different projects and achieve company goals.
· Promote and adhere to OMass’ values of being Ambitious, Responsible, Innovative, Focused, Caring and Collaborative.
Benefits
OMass offers an excellent benefits package including:
· Private Health Insurance
· Health and wellbeing cashback scheme
· Life Assurance and Income Protection
· Participation in Employee Equity Scheme
· 25 days annual leave, plus bank holidays
· Pension Scheme offering 6% employer contribution
· Learning and Development Opportunities
· Company social events
Any queries relating to the role can be sent to .
OMass Therapeutics values diversity and is committed to equality of opportunity, we also have full responsibility to ensure that all employees are eligible to work and live in the UK.
