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Associate Director, Research and Computing Operations

Asklepios Biopharmaceutical Inc
Edinburgh
1 week ago
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Associate Director, Research and Computing Operations page is loaded Associate Director, Research and Computing Operations Apply locations Edinburgh, UK time type Full time posted on Posted 2 Days Ago job requisition id R25-77 AskBio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular, and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure, limb-girdle muscular dystrophy, multiple system atrophy, Parkinson’s disease, and Pompe disease. AskBio’s gene therapy platform includes Pro10, an industry-leading proprietary cell line manufacturing process, and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, the company has generated hundreds of proprietary capsids and promoters, several of which have entered pre-clinical and clinical testing.
Our vision:

Pioneering science to create transformative molecular medicines.
Our mission:

Lead innovative science and drive clinical outcomes to transform people's lives.
Our principles:
Advance innovative science by pushing boundaries.

Bring transformative therapeutics to patients in need.

Provide an environment for employees to reach their fullest potential.

Our values:
Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.

Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.

Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.

Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.

Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.

Position Summary
We're seeking an Associate Director, Research Computing Operations to lead and transform our scientific computing environment in support of our cutting-edge gene therapy research. This senior leadership position will drive the strategy and execution of research computing initiatives, working in close partnership with our Bioinformatics, AI/ML, and Global IT Infrastructure teams. The role focuses specifically on advancing our scientific computing capabilities through operational excellence, while ensuring our research teams can maximize the value of our high-performance computing investments.
As a key member of the technology leadership team, this position will be responsible for the day-to-day operations and strategic evolution of our research computing environment. The successful candidate will combine deep technical expertise in scientific computing with strong business acumen to deliver innovative solutions that accelerate our research mission. While Global IT Infrastructure maintains our enterprise technology foundation, this role focuses exclusively on the specialized computing needs of our scientific teams, including high-performance computing, GPU-accelerated workflows, and research data management.
Job Responsibilities
Serve as the primary local IT Infrastructure contact for Edinburgh's Bioinformatics and AI/ML teams

Manage and optimize scientific computing infrastructure, including GPU clusters, high-performance storage systems, and virtualized environments

Collaborate with global IT teams to ensure infrastructure alignment with scientific computing needs

Lead technical planning and implementation of infrastructure improvements

Provide technical guidance on architecture decisions affecting scientific workflows

Manage and optimize WEKA storage systems and VSphere virtual environments

Support Linux-based scientific computing environments, leveraging managed services as appropriate

Implement and maintain monitoring solutions for complex computing environments

Participate in capacity planning and performance optimization initiatives

Drive infrastructure automation and continuous improvement

Manage relationships with vendors and technical partners

Vendor & Contract Management:
Manage third-party Linux support contract and contractor relationships

Define and monitor service level agreements

Ensure contractor compliance with company security policies

Review and approve contractor work

Manage vendor performance and escalations

Security & Compliance:
Act as primary point of contact for parent company security audits

Develop and maintain security compliance documentation

Coordinate and respond to penetration testing activities

Implement security recommendations and remediation plans

Ensure infrastructure meets corporate security standards

Participate in security incident response planning

Business Continuity:
Lead disaster recovery planning for scientific computing infrastructure

Coordinate and execute DR testing

Maintain DR documentation and procedures

Develop and maintain business continuity plans

Ensure RPO/RTO objectives are met

Financial Planning & Technical Debt:
Develop long-term capital planning for infrastructure

Manage infrastructure budget and forecasting for AskBio European locations

Identify and track technical debt

Create remediation plans for technical debt

Provide cost-benefit analysis for infrastructure investments

Manage infrastructure lifecycle planning

Develop business cases for infrastructure improvements

Key Competencies:
Technical:
Infrastructure architecture and design

Performance optimization

Problem-solving and troubleshooting

Security best practices

Technical documentation

Business & Management:
Contract negotiation and management

Budget planning and control

Risk management

Audit response and compliance

Strategic planning

Vendor management

Cost-benefit analysis

Interpersonal:
Strong communication skills

Stakeholder management

Team collaboration

Conflict resolution

Customer service orientation

Ability to bridge technical and scientific domains

Leadership:
Technical leadership

Project management

Mentoring and knowledge transfer

Change management

Strategic thinking

Impact Metrics: Success in this role will be measured by:
Infrastructure stability and performance improvements

Stakeholder satisfaction levels

Project delivery effectiveness

Technical problem resolution metrics

Team collaboration effectiveness

Innovation and process improvements

Note: This position requires occasional travel to other company locations and may require some out-of-hours support during critical maintenance windows or emergencies.
This role represents a critical position in our organization, bridging technical expertise with scientific computing needs while fostering strong working relationships between global teams.
Minimum Requirements
Bachelor's degree in Computer Science, Engineering, or related field

8+ years of experience in infrastructure engineering roles

Experience with high-performance computing environments

Proven experience supporting GPU-accelerated computing environments

Strong understanding of storage systems and networking

Experience with infrastructure monitoring and optimization tools

Demonstrated ability to work with scientific computing workflows

Experience managing vendor relationships and contracts

Knowledge of IT security and compliance requirements

Experience with disaster recovery planning and testing

Understanding of IT financial planning and budgeting

Experience with audit responses and compliance documentation

Strong experience with Linux administration and engineering

Extensive knowledge of virtualization technologies, particularly VSphere

Preferred Education, Experience and Skills
Experience with WEKA storage systems

Knowledge of AI/ML infrastructure requirements

Experience supporting bioinformatics workflows

Familiarity with container technologies (Docker, Kubernetes)

Experience with infrastructure automation tools

Understanding of scientific computing software and frameworks

Previous experience in biotech or pharmaceutical industries

Experience with cloud platforms (AWS, Azure)

ITIL certification

Security certifications (CISSP, CISM, or similar)

Experience with GxP compliance

Experience with pharmaceutical industry regulations

Previous experience managing technical debt in regulated environments

AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at .
Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio, through any medium, will be deemed the sole property of AskBio

unless

the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio, no fee or payment of any kind will be paid to the agency.

About Us

AskBio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular, and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure, limb-girdle muscular dystrophy, multiple system atrophy, Parkinson’s disease, and Pompe disease. AskBio’s gene therapy platform includes Pro10, an industry-leading proprietary cell line manufacturing process, and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, the company has generated hundreds of proprietary capsids and promoters, several of which have entered pre-clinical and clinical testing.

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