Antibody Engineering Lead – Therapeutic Discovery

Join a fast-scaling biotech that’s innovating at the intersection of protein science and animal health. We're engineering novel antibody formats, including VHH single-domain antibodies, to target previously untreatable diseases. If you're an expert in molecular biology and protein engineering with a passion for translational science, this is your chance to lead high-impact work in a collaborative, mission-driven environment.

What You’ll Do

· Lead design and engineering of therapeutic antibodies, including VHHs, bispecifics, and fusion proteins

· Apply advanced molecular biology techniques (e.g. vector design, cloning, mutagenesis) to antibody construct development

· Oversee optimisation of antibody properties for veterinary applications, including immunogenicity and developability

· Collaborate cross-functionally with expression, assay, and CMC teams to drive candidate progression

· Supervise and mentor lab scientists, ensuring scientific excellence and career development

· Contribute to project strategy, scientific roadmaps, and communication with leadership and partners

What You’ll Bring

· Proven expertise in antibody/protein engineering, with experience designing therapeutic antibodies

· Strong molecular biology foundation including cloning, construct design, and mutagenesis

· Familiarity with complex antibody formats (e.g. VHH, bispecifics, fusion proteins)

· Understanding of developability challenges: immunogenicity, manufacturability, and biophysical profiling

· Collaborative mindset and strong communication skills across technical and non-technical teams

· Experience leading or mentoring in a biotech or fast-paced research setting

Why Join Us?

We’re building a new category in therapeutics; our cutting-edge antibody platform has already delivered clinical success, and we’re just getting started. You can expect a career focussed on impact & Innovation, with modern labs, a collaborative culture and mission-driven science.

Benefits Include

· Competitive salary & equity aligned to experience

· Private health insurance (including dental & optical options)

· Access to mental health & wellbeing support

· Paid sick leave and flexible working policies

· Continuous professional development & leadership mentoring

· A diverse and inclusive culture where your voice matters

If you are ready to advance your career and have the skills and ambition for this position, please email your CV toHattie Daviesat or contact +44 (0)1273 059 650.

Key words:

Antibody Engineering, Protein Engineering, Molecular Biology, VHH Antibodies, Single-Domain Antibodies, Nanobodies, Bispecifics, Fusion Proteins, Antibody Discovery, Therapeutic Antibodies, Antibody Optimisation, Humanisation, Affinity Maturation, Stability Engineering, Developability, Expression Systems, Protein Purification, Cloning, Vector Design, Mutagenesis, Golden Gate Cloning, Bagel 1 Cloning, Synthetic Biology, Translational Research, Drug Discovery, Biologics Development, Biotech, Pharmaceutical R&D, Therapeutic Design, Project Leadership, Antibody Formats, Modular Antibodies, Immunogenicity, Structural Biology, Functional Screening, Multispecifics, CDMO, Target Validation, Candidate Selection, Therapeutic Pipeline, Lab Automation, Cross-Functional Collaboration, Mentorship, Molecular Cloning, Protein Therapeutics, Gene Assembly, In Vitro Assays, Antibody Selection, Early-Stage Discovery, Applied Research, Veterinary Biologics, Animal Health, Antibody Platforms, Translational Science, Biopharmaceuticals