Biotechnology Jobs

Alloy Therapeutics UK Ltd · Cambridge · £45,000 – £50,000 pa

Design and build large-scale synthetic gene loci and transgenic platforms for antibody discovery, using CRISPR/Cas9, RMCE and site-specific integrases. Hands-on molecular biology including PCR, NGS, plasmid construction and flow-cytometric immunophenotyping, within a small multidisciplinary team working from dry-lab design to wet-lab validation.

CureAge Therapeutics · London

Lead the computationally guided design of a lipid nanoparticle delivery platform, applying chemical and biophysical principles to optimise LNP composition and formulation. Use AI-enabled chemistry, cheminformatics, predictive models and molecular modelling to prioritise formulation components, working closely with the experimental team and founding team in a small start-up.

Evotec · Macclesfield

Lead the design, engineering, expression, purification and characterisation of complex biologic therapeutics including monoclonal, bispecific and multispecific antibodies. Acts as biologics scientific lead on client-facing drug discovery programmes, mentoring junior scientists and shaping project strategy within a multidisciplinary Protein Sciences team.

Ellison Institute of Technology · Oxford · £40,000 pa

Postdoctoral role in the Liu Lab for Synthetic Evolution, designing and troubleshooting experiments, analysing complex data with computational and statistical tools, and publishing high-quality research. The lab invented OrthoRep for continuous accelerated gene evolution, with projects spanning antibody sequence-affinity datasets, enzyme sequence-function maps, and de novo gene function emergence. Involves mentoring junior researchers and collaborating across multidisciplinary teams.

Ellison Institute of Technology · Oxford

Develops and optimises high-throughput enzyme assays to characterise plant protein variants from AI-assisted design and evolutionary discovery. Works with computational scientists, automation engineers and roboticists to build scalable protein expression, purification and biochemical characterisation pipelines, informing protein engineering and crop yield decisions.

ISR Recruitment · Oxford · £520 – £532 pd

Lead a laboratory-based immunology team, designing in vitro pharmacology assays and coordinating in vivo efficacy studies with CROs to advance biologic therapies for autoimmune diseases. Involves target identification, ex vivo profiling, and cross-functional work with protein engineering, biomarkers and translational medicine, plus IND documentation and publications.

Evotec · Abingdon

Owns Evotec's in silico therapeutics design capability, uniting computational chemistry, generative and modality design (small molecules, peptides, protein engineering, degraders, molecular glues) and predictive ADMET/safety under one mandate. A newly created unit within the In Silico & AI group with an explicit build mandate: set technical vision, grow a multi-site team, and industrialise repeatable, benchmarked methods across partner programmes.

Basecamp Research · London

Owns the peptide and protein platform as a commercial product, spanning market and competitive intelligence, target product profiles, roadmap and packaging decisions, and go-to-market positioning. Sits between model, data and science teams and business development, and is accountable for partner engagement and revenue generation. Requires deep peptide therapeutics and licensing deal expertise.

Bond Williams · London · £40,000 – £50,000 pa

Hands-on lab role expressing and purifying recombinant proteins using bacterial, cell-free and other systems, plus preparing buffers and reagents to precise specs. You'll run QC and release testing (SDS-PAGE, purity, activity assays), maintain batch records in an eQMS, write SOPs and support deviations and CAPAs while optimising and scaling production processes.

Basecamp Research · London

Owns R&D extraction workflow development, adapting and optimising metagenomic DNA/RNA extraction methods across diverse, low-biomass and inhibitor-rich sample types, including HMW extractions for long-read sequencing. Designs controlled experiments, transfers validated methods to production and a global partner network, and works in a data-first lab environment feeding a large gene atlas.

Nuclera · Cambridge

Formulate, dispense and quality-control reagents for a protein discovery platform, operating lab equipment such as pipettes, centrifuges and UPLC systems. The role covers batch documentation, inventory management via ERP and troubleshooting production deviations, working closely with R&D, QA and Supply Chain in a fast-paced lab environment.

Sartorius · Glasgow

Performs laboratory techniques under GMP conditions, including cell-based assays, ELISAs and protein characterisation, to test biological products such as monoclonal antibodies, cell and gene therapies and vaccines. Also manages stock and reagents, maintains traceability records, and prepares controlled documentation like SOPs and risk assessments within a nine-person team.

Vertex Pharmaceuticals · Oxford

Lead the DMPK team at Vertex's Oxford site, shaping strategy and operations while sitting on both the Global DMPK and Oxford Site leadership teams. The role directs ADME science across discovery and development programmes, partners with Medicinal Chemistry, Biology, Preclinical Safety and Clinical Pharmacology, and oversees regulatory documentation such as INDs and marketing applications. It combines deep small-molecule DMPK expertise with hiring, mentoring and resource planning.

Moderna · Oxford

Designs and delivers immunogenicity and bioanalytical strategies for regulated clinical programmes, developing ADA, nAb, PK and PD assays using ELISA, MSD and cell culture. Works with multidisciplinary teams to validate assays, manage reagents and SOPs, and integrate digital and AI-enabled tools. Site-based at Harwell within a growing mRNA-focused team.

Francis Crick Institute · London · £47,500 pa

Investigates how protein machines remodel microtubules using cryo-electron microscopy, protein reconstitution and fluorescence microscopy. As an early member of a new lab, you will shape the research programme, establish experimental approaches and develop scientific independence while working closely with the group leader.

University of Oxford · Oxford · £39,424 – £43,984 pa

Carries out laboratory research on synthetic genome DNA assembly, generating constructs and testing new approaches using recombinant DNA methylases. Involves molecular cloning, long DNA molecule extraction, bacterial culture and recombinant protein production and purification, with scope for some bioinformatic analysis. Based in a well-equipped Oxford lab, collaborating on translation of synthetic chloroplast genomes into crop plants such as potato and wheat.