Latest regulatory affairs Jobs

Director, Oncology Translational Medicine

Lead the development and execution of biomarker and translational medicine strategies for late-stage oncology programs, integrating cutting-edge technologies to inform clinical decision-making and patient stratification. Collaborate across cross-functional teams to align biomarker strategies with clinical development and regulatory goals. Drive innovation through translational research and real-world data integration to support drug development and life cycle management.

GSK Canterbury, United Kingdom £189,750 – £316,250 pa

Clinical Development Medical Director - Cardiovascular

Lead clinical development for cardiovascular programs within GSK’s Respiratory, Immunology & Inflammation Research Unit, driving translational and clinical strategies from early to late stages. Provide medical oversight, design clinical development plans, and collaborate across functions to deliver innovative medicines addressing unmet patient needs. Work in a hybrid model with a future relocation from Stevenage to Cambridge by 2029.

GSK Stevenage, United Kingdom

Hybrid Permanent

Principal Scientist, Immunogenicity and Ligand Binding Assays

This role involves leading and executing phase-appropriate bioanalytical strategies for immunogenicity and ligand binding assays (LBA) within Moderna’s mRNA-LNP therapeutic pipeline. The Principal Scientist will oversee assay development, validation, and sample analysis, ensuring regulatory compliance and scientific rigor across clinical programs. The position emphasizes collaboration with cross-functional teams, integration of emerging technologies including AI-enabled tools, and contribution to regulatory submissions and data interpretation in a GcLP-compliant environment.

Moderna Oxford, United Kingdom

Hybrid Permanent

Sr. Research Associate, Bioanalytical & Molecular Assays - Ligand Binding Assays

This role involves developing, validating, and executing ligand-binding and cell-based assays to support mRNA medicine development. The candidate will generate pharmacodynamic and immunogenicity data in a regulated GcLP environment, manage critical reagent characterization, and contribute to clinical sample testing using Watson LIMS. The position emphasizes scientific rigor, regulatory compliance, and collaboration within a high-performance team advancing novel bioanalytical assays.

Moderna Oxford, United Kingdom

Hybrid Permanent

Clinical Development Medical Director - Neuromuscular

Leads global clinical development programs in neuroscience, with a focus on neuromuscular or related disorders. Provides medical leadership across trial design, regulatory submissions, and safety monitoring, collaborating with cross-functional teams and external stakeholders. Plays a strategic role in advancing innovative therapies through clinical execution and scientific insight.

Novartis London, United Kingdom £83,510 – £155,090 pa

Hybrid Permanent

Translational Medicine Expert – Dermatology, Associate Director

This role involves providing medical and scientific leadership in translational medicine for dermatology programs, spanning early to late-stage drug development. The expert will design and implement strategies for clinical pharmacology, biomarker development, and regulatory submissions, while leading cross-functional teams and supporting in-licensing opportunities. Work includes oversight of clinical studies, publication strategy, and engagement with regulatory and external stakeholders.

Novartis London, United Kingdom £67,900 – £126,100 pa

Hybrid Permanent

Global Development Lead, Internal Medicine, Sr. Director (MD)

This role involves leading clinical development for Internal Medicine assets within Pfizer's Research & Development division, with a focus on obesity-related therapies. The Global Development Lead serves as the primary clinical accountability point, designing and executing global clinical development plans, regulatory submissions, and cross-functional team leadership. The position requires deep therapeutic expertise in endocrinology or internal medicine, extensive experience in Phase 1–3 trials, and strategic input into product development, digital innovation, and patient engagement initiatives.

Pfizer

On-site Permanent

Global Development Lead, Internal Medicine, Sr. Director (MD)

This role involves leading clinical development for Internal Medicine assets at Pfizer, with end-to-end accountability for designing, executing, and interpreting global clinical trials. The individual will serve as the primary clinical leader on cross-functional teams, shaping development plans, supporting regulatory submissions, and engaging with external stakeholders. A strong emphasis is placed on strategic innovation, team leadership, and therapeutic expertise in obesity and endocrinology.

Pfizer

On-site Permanent

Director, Search & Evaluation Early TA Lead (CVR and Haem)

Leads strategic sourcing and evaluation of early-stage external innovation in Hematology or Cardiovascular/Renal therapeutic areas. Identifies and advances preclinical to Phase 1 assets, drives due diligence, and shapes partnering strategies within cross-functional teams. Represents the therapeutic area externally, building relationships with biotech, academia, and investors to strengthen the innovation pipeline.

CSL

On-site Permanent

Executive Director, Asset Strategy Leadership

Leads strategic positioning of clinical assets in oncology and immunology, leveraging AI-driven insights from the Recursion OS to inform go/no-go decisions, competitive differentiation, and portfolio prioritization. Works cross-functionally with clinical, platform, and business development teams to align resource allocation and advance transformative medicines. Focuses on integrating mechanistic, biomarker, and market data to build compelling narratives for internal and external stakeholders.

Recursion North Tyneside, NE29 8EP, United Kingdom £297,000 – £356,400 pa

Director, Generative AI – Chemical Development

Leads the strategy and implementation of Generative AI and agentic workflows in chemical development to accelerate CMC processes and scientific decision-making. Drives adoption of AI in regulated environments, focusing on use cases like knowledge mining, report generation, and experiment planning. Works across scientific, compliance, and digital teams to embed responsible, scalable AI into routine workflows.

AstraZeneca Macclesfield, United Kingdom

Pathology Director

Leads medical and technical oversight of an accredited diagnostic laboratory supporting clinical trials and biomarker development. Provides expert interpretation of pathology and biomarker data, ensures regulatory compliance, and drives innovation in digital pathology and companion diagnostics. Works cross-functionally to integrate advanced diagnostic methods into drug development programs.

AstraZeneca Cambridge, United Kingdom

Team Lead, Master Scheduler, Engineering

The Master Scheduler, Engineering is responsible for strategic planning and coordination of engineering projects, ensuring efficient resource use and adherence to timelines. This role involves leading cross-functional collaboration, monitoring project progress, mitigating risks, and ensuring compliance with regulatory standards. The position supports the delivery of innovative T cell therapies within a fast-paced biopharmaceutical environment.

Autolus Stevenage, United Kingdom

Field Service Engineer - Medical Diagnostics - South Region - Exeter - London - Kent

Perform on-site and remote technical support for Roche’s diagnostic systems, including troubleshooting, preventive maintenance, and customer training across the South Region. Use advanced diagnostic tools to resolve electro-mechanical faults and ensure regulatory compliance. Work within a customer-centric team to maximise system uptime and operational efficiency in clinical environments.

Roche United Kingdom

Field Service Engineer - Medical Diagnostics -Central Region Wales, Wirral and East Anglia

This role involves providing on-site and remote technical support for Roche’s diagnostic systems across medical laboratories and healthcare facilities. You’ll troubleshoot electro-mechanical faults, perform preventive maintenance, and deliver training to ensure optimal system uptime and customer proficiency. The position emphasizes compliance, reporting, and collaboration within a customer-centric field support team.

Roche United Kingdom