Latest Drug Discovery Jobs

Software Engineer (LLM Engineering), London

This role involves designing and building scalable, secure systems to integrate large language models into scientific discovery workflows. You'll develop LLM infrastructure, agentic tooling, and evaluation frameworks while collaborating closely with AI researchers and cross-functional teams. The position emphasizes first-principles thinking and production-grade engineering to advance AI-driven drug discovery.

Isomorphic Labs London, United Kingdom

ML Research Engineer, London

Develop and optimise cutting-edge AI models at the intersection of machine learning and drug discovery, translating research into scalable, production-ready systems. Work on foundational models like Diffusion networks, Transformers, and GNNs, building robust infrastructure and data pipelines while collaborating closely with scientists. Focus on advancing a digital biology platform to accelerate rational drug design across multiple therapeutic areas.

Isomorphic Labs London, United Kingdom

On-site Permanent

Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation

Lead and execute model-based drug development strategies in oncology, applying advanced pharmacometric and AI/ML techniques to optimize dose selection, trial design, and regulatory submissions. Drive innovation in clinical pharmacology through cross-functional collaboration and external engagement. Operate in a science-driven environment focused on accelerating the development of novel cancer therapies.

GSK US$188,100 – US$313,500 pa

Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation

Lead clinical pharmacology and modelling & simulation efforts for oncology drug development, applying AI/ML and quantitative methods to optimise dosing, trial design, and regulatory strategy. Drive innovation in model-informed drug development across small molecules, biologics, and antibody-drug conjugates. Collaborate with cross-functional teams to accelerate therapies to patients using advanced pharmacometric and machine learning techniques.

GSK £188,100 – £313,500 pa

Director, Clinical Pharmacology

Lead clinical pharmacology and pharmacometrics strategy for rare disease and oncology programs, designing studies and guiding regulatory submissions. Oversee modeling and simulation to inform dose selection and accelerate drug development. Collaborate across translational, clinical, and preclinical teams in a tech-driven biopharma environment.

Recursion United Kingdom US$212,900 – US$297,000 pa

Hybrid Permanent

Vaccines Safety Sciences Lead

Leads vaccine safety sciences functions, ensuring compliance with pharmacovigilance regulations and global safety standards. Oversees signal detection, safety data analysis, and regulatory documentation while guiding process improvements and cross-functional initiatives. Manages teams and supports regulatory inspections, safety reporting, and the implementation of data visualization tools for enhanced decision-making.

CSL

Hybrid Permanent

Associate Director, Clinical Trial Disclosure & Transparency

This role leads global clinical trial disclosure and transparency strategy, ensuring compliance with international regulations such as FDAAA 801, EU CTR, and MHRA requirements. The individual oversees study registration, results reporting, and layperson summaries, while managing redaction of confidential information for public release. They act as a key liaison with regulatory bodies and internal teams, driving process efficiency and vendor performance across the clinical development lifecycle.

CSL

Senior Applied AI & ML Engineer - Evinova

This role involves designing and building applied AI and machine learning systems to transform clinical trial design, using GenAI, agentic systems, and multi-source data integration. The engineer will work on production-grade solutions that improve trial success rates, reduce development time, and lower costs, with a strong emphasis on scientific rigour and real-world impact. The position requires blending deep technical expertise in ML and software engineering with domain knowledge in drug development and regulated environments.

AstraZeneca London, United Kingdom

Senior Scientist – Diagnostic Deployment

This role involves hands-on development, optimisation, and validation of tissue-based diagnostic assays, primarily using histology and immunohistochemistry (IHC), to support AstraZeneca's clinical trials. The scientist will integrate digital and computational pathology tools, ensure compliance with regulatory standards like CAP/CLIA and ISO, and enhance laboratory workflows through LIMS integration. The position emphasizes scientific rigour, cross-functional collaboration, and innovation in oncology diagnostics.

AstraZeneca Cambridge, United Kingdom

Senior Research Associate, Bioanalytical & Molecular Assays

This role involves developing, qualifying, and validating molecular bioanalytical assays—such as qPCR, ddPCR, and RT-qPCR—to support clinical pharmacokinetic and pharmacodynamic studies within a GCLp-compliant environment. The scientist will work closely with cross-functional teams to ensure robust data generation, maintain regulatory compliance, and integrate emerging digital and automation technologies into workflows. A strong focus on reagent management, assay documentation, and continuous process improvement is central to the position.

Moderna Oxford, United Kingdom

Hybrid Permanent

Medical Device Programme Lead

Balance technical, regulatory and commercial challenges in this fulfilling roleThis highly regraded Cambridge-based medical technologies company is seeking a proven engineering leader to help guide high-value development programmes from concept through to transfer to manufacture. Your leadership will accelerate development...

ECM Selection Cambridge, Cambridgeshire, United Kingdom £75,000 – £95,000 pa

Analyst, Quality Control, Microbiology

This role involves performing routine environmental monitoring, water sampling, and microbiological testing to support GMP quality control for mRNA products. The analyst will execute tests including sterility, bioburden, endotoxin, and TOC, while supporting method transfers, validations, and compliance with cGMP standards. The position requires strong documentation practices, collaboration with cross-functional teams, and active participation in quality systems such as investigations and audits.

Moderna

On-site Permanent

Associate Director, Statistical Programming

Lead a global team of statistical programmers, driving standardization, innovation, and quality in clinical trial data analysis. Develop programming strategies using modern tools like R, Git, and AI-enabled technologies, ensuring audit-ready deliverables and alignment with biostatistics and data management. Provide technical leadership and influence global drug development strategy across phases I–IV studies.

Novartis London, United Kingdom £67,900 – £126,100 pa

Hybrid Permanent

Senior Principal Data Scientist

This role involves leading advanced data science initiatives in drug development, using machine learning, AI, and statistical modeling on clinical and real-world data. The scientist will translate complex business questions into analytical solutions, develop innovative algorithms, and collaborate with internal and external stakeholders to inform decision-making. Work includes hands-on analysis, pipeline development, and methodological innovation using R, Python, and data integration tools.

Novartis London, United Kingdom £57,050 – £105,950 pa

Senior Director, Biostatistics

Leads the Biostatistics function, building and managing a team of statisticians and programmers while providing strategic statistical input across clinical development programs. Plays a central role in study design, regulatory engagement, and innovation in methodologies tailored to gene therapy and rare diseases. Works closely with cross-functional teams and global regulatory agencies to ensure robust, compliant, and efficient development of gene therapies.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent