Latest Engineering Jobs

(Fixed-Term) Manufacturing Associate I

Operate and maintain equipment in a cGMP-compliant, highly automated mRNA vaccine production environment at Moderna's Oxford facility. Perform production operations, support quality assurance, troubleshoot issues, and contribute to continuous improvement initiatives using digital systems and advanced manufacturing technologies. Work within a 2-2-3 rotating shift pattern to ensure reliable, safe, and compliant vaccine manufacturing.

Moderna Oxford, United Kingdom

Machine Learning Scientist - Quantum Chemistry

This role involves developing machine learning models grounded in quantum chemistry to accelerate small-molecule drug discovery. The scientist will create synthetic datasets using quantum mechanical methods, build scalable and reproducible ML pipelines, and collaborate with computational and experimental teams to model molecular energetics and protein–ligand interactions. Work contributes directly to drug design tools at Roche, with opportunities for scientific publication and open-source contributions.

Roche Welwyn Hatfield, United Kingdom

Hybrid Permanent

Senior Applied AI & ML Engineer - Evinova

This role involves designing and building applied AI and machine learning systems to transform clinical trial design, using GenAI, agentic systems, and multi-source data integration. The engineer will work on production-grade solutions that improve trial success rates, reduce development time, and lower costs, with a strong emphasis on scientific rigour and real-world impact. The position requires blending deep technical expertise in ML and software engineering with domain knowledge in drug development and regulated environments.

AstraZeneca London, United Kingdom

Associate Director, CMC Regulatory Affairs, International

This role involves leading CMC regulatory strategies for international submissions, including IND/CTA/BLA/MAA filings, with a focus on mRNA-based medicines. The individual will guide global regulatory compliance, interact with health authorities, and support quality and manufacturing teams across therapeutic areas like vaccines, oncology, and rare diseases. It requires deep expertise in biologics CMC regulations and a proactive approach to navigating complex regulatory landscapes.

Moderna London, United Kingdom

On-site Permanent

ML Research Engineer, London

Develop and optimise cutting-edge AI models at the intersection of machine learning and drug discovery, translating research into scalable, production-ready systems. Work on foundational models like Diffusion networks, Transformers, and GNNs, building robust infrastructure and data pipelines while collaborating closely with scientists. Focus on advancing a digital biology platform to accelerate rational drug design across multiple therapeutic areas.

Isomorphic Labs London, United Kingdom

On-site Permanent

Research Scientist (Applied LLMs), London

A Research Scientist focused on applying Large Language Models to drug discovery, working in interdisciplinary teams to develop novel AI-driven approaches for biological and chemical challenges. The role involves advancing LLM techniques such as post-training, reasoning, tool-use, and alignment within a cutting-edge AI research environment. Collaboration with scientists and engineers is central to developing predictive models that accelerate rational drug design.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Finance Portfolio Analytics Manager

This role involves building and leading the analytical framework for R&D investment decisions at a global biopharma company. The Finance Portfolio Analytics Manager designs financial models, valuation tools, and dashboards to translate scientific and clinical data into quantified financial impact. They lead strategic analyses, improve forecasting methodologies, and provide data-driven insights to senior leadership across complex portfolio decisions.

GSK

Head of RTSM (Randomization and Trial Supply Management)

Lead the RTSM function for clinical trials, designing and delivering patient-focused randomization and trial supply strategies across Phase I–IV programs. Partner with cross-functional teams and vendors to ensure reliable supply and randomization systems, while building team capability and driving process improvements aligned with clinical development and regulatory standards.

GSK €119,250 – €198,750 pa

Manager, Computational Biology (Early Oncology)

Lead a team of computational biologists to integrate multi-omics data for oncology target discovery and validation, while actively contributing to data analysis and cross-functional decision-making. Develop biomarker strategies and patient stratification approaches to guide therapeutic development. Collaborate closely with biologists, chemists, and clinical teams to advance drug programs using high-dimensional datasets and scalable computational methods.

Recursion United Kingdom US$151,800 – US$230,000 pa

Hybrid Permanent

Machine Learning Scientist - Quantum Chemistry

Develop machine learning models grounded in quantum chemistry to accelerate small-molecule drug discovery. Create synthetic datasets using quantum mechanics and build scalable, deployable pipelines integrated into molecular design tools. Collaborate with computational and experimental scientists to advance drug discovery through publications and open-source contributions.

Roche

Hybrid Permanent

Senior Computational Biologist – Early Discovery Immunology

A Senior Computational Biologist will drive target discovery in immunology and inflammatory diseases by integrating multi-omics data (phenomics, transcriptomics, genomics, proteomics) to nominate and validate novel therapeutic targets. The role involves developing computational methods, collaborating with cross-functional teams, and translating complex analyses into actionable drug discovery programs using Recursion’s AI-driven platform.

Recursion United Kingdom £151,800 – £220,660 pa

Hybrid Permanent

PhD Studentship in Computer Science: Programming Matter - Dynamic DNA Data Structures for Molecular Information Storage and Computing

This PhD studentship focuses on developing dynamic DNA data structures for molecular information storage and computing, combining computational design with experimental lab work. The project builds on pioneering research in DNA-based stack structures and aims to create novel molecular data structures such as queues, deques, and priority structures. The candidate will work within an interdisciplinary team, designing, modelling, and validating DNA/RNA systems and molecular circuits for in vitro or cellular applications.

Newcastle University Newcastle upon Tyne, Northern England, United Kingdom £21 pa

Contract

Senior Mechanical Engineer - Complex Sensor Design

Design and develop complex sensor-based devices and instruments from concept through to manufacturing and deployment. Work closely with world-class engineers and scientists on multidisciplinary research projects, taking hands-on responsibility for mechanical design and technical leadership within the team. Devices range from handheld units to large-scale systems for detecting and measuring various physical parameters.

Newton Colmore Cambridge, Cambridgeshire, United Kingdom £50,000 – £70,000 pa

Bio-ML Scientist (Metabolic Modelling) - Generative Biology Institute

Develop and deploy machine learning systems to advance synthetic biology, genome design, and metabolic modelling in close collaboration with wet lab scientists and computational teams. Focus on building scalable, biology-centric AI solutions using diverse data modalities and integrating with genome-scale metabolic models. Work within a multidisciplinary research environment to co-create projects and drive innovation from concept to publication.

Ellison Institute of Technology Oxford, United Kingdom

Hybrid Permanent

Media and Glass Technician - Generative Biology Institute

This role involves preparing laboratory media, buffers, and agar plates while maintaining sterile glassware and consumables to support high-quality research at the Generative Biology Institute. The technician ensures consistent, contamination-free supplies using aseptic techniques and standard operating procedures, enabling scientists to focus on engineering biology breakthroughs. The position emphasizes precision, routine quality control, equipment operation, and collaboration within a dedicated support team in a state-of-the-art research environment.

Ellison Institute of Technology Oxford, United Kingdom

On-site Permanent