Jobs in Stoke-on-trent

Principal Scientist, Immunogenicity and Ligand Binding Assays

This role involves leading scientific strategy and execution for immunogenicity and ligand binding assays (LBA) in support of Moderna’s mRNA-LNP therapeutic programs. The Principal Scientist will oversee regulated bioanalytical activities including assay development, validation, and sample analysis, ensuring compliance with GcLP, GLP, and GCP standards. The position plays a key role in clinical development by generating high-quality data to inform regulatory submissions and advance innovative medicines, with opportunities to engage in AI-enabled and digital analytical approaches.

Moderna

Hybrid Permanent

Sr. Research Associate, Bioanalytical & Molecular Assays - Ligand Binding Assays

Develops and validates ligand-binding and cell-based assays to support clinical programs for mRNA medicines. Performs pharmacodynamic and immunogenicity testing in compliance with GcLP, using platforms like Thermo Watson LIMS. Contributes to assay development, reagent management, and regulatory documentation in a fast-paced, innovative lab environment.

Moderna

Hybrid Permanent

(Fixed-Term) Manufacturing Associate I

This role involves operating and maintaining equipment in a cGMP-regulated mRNA vaccine production environment, ensuring safe and compliant manufacturing processes. The associate will execute production operations, support quality assurance, troubleshoot technical issues, and contribute to continuous improvement initiatives. Work is conducted in a highly automated, digitally enabled facility with a focus on operational excellence and innovation in mRNA technology.

Moderna

Senior Manager, Packaging Engineering

Lead the technical development and implementation of a new labeling and secondary packaging operation at Moderna’s Harwell site, from initial design through commissioning and validation. Establish maintenance strategies, ensure GMP compliance, and drive continuous improvement using engineering excellence principles and digital tools. Build and lead a high-performing engineering team to support long-term operational success in a regulated biotech environment.

Moderna

Hybrid Permanent

Principal Scientist, Bioanalytical & Molecular Assays

This role involves leading the development and validation of advanced molecular assays—including RT-qPCR, dPCR, and NGS-based methods—for clinical biomarker programs at Moderna. The scientist will drive end-to-end assay lifecycle management, ensure compliance with GCLP and regulatory standards, and collaborate across multidisciplinary teams to generate high-quality genomic data. A key focus is integrating genomics, bioinformatics, and clinical insights to support drug development and inform future pipeline strategies.

Moderna

Hybrid Permanent

Scientist, Clinical Biomarker Laboratory, Immuno-Assays - Cell Based

This role involves leading the development, qualification, and execution of complex cell-based immunoassays to support Moderna’s clinical trials across multiple therapeutic areas. The scientist will generate high-quality, regulatory-compliant data using advanced immunological techniques and serve as a subject matter expert within cross-functional teams. Emphasis is placed on innovation, scientific rigor, and integration of emerging technologies including digital and AI-enabled workflows in a GCP/GLP-regulated environment.

Moderna

Hybrid Permanent

Senior Automation Engineer, Laboratory Automation & Biobanking

This role involves designing and optimizing automated laboratory workflows for biomarker testing and sample management using advanced liquid handling systems like Hamilton platforms. The engineer will lead integration of automation with data systems, develop data pipelines, and support AI-enhanced laboratory operations while ensuring compliance with GLP/GCLP standards. Collaboration with digital, QA, and vendor teams is key to delivering scalable, high-throughput solutions in a regulated clinical environment.

Moderna

Hybrid Permanent

Sr. Manager, Site Budgets and Contracts

This role involves leading the creation and management of investigator site budgets and contracts for global clinical trials, using Grants Manager and FMV benchmarking tools. The Senior Manager collaborates with CROs, Legal, and Clinical Operations to ensure site budgets align with study forecasts and are executed on time. Responsibilities include strategic planning, contract negotiation oversight, risk identification, and process improvement within an outsourced trial model.

Moderna

Hybrid Permanent

Associate Director, Resilience Strategic Partnerships – UK

Lead the execution of Moderna’s landmark Long-Term Strategic Partnership with the UK Government, coordinating cross-functional teams across R&D, manufacturing, and access to deliver on public health commitments. Serve as the primary liaison with senior government stakeholders including UKHSA and DHSC, ensuring alignment, governance, and delivery against strategic objectives. Drive program management, risk mitigation, and stakeholder engagement in a high-visibility role shaping the future of mRNA vaccine development and biomanufacturing in the UK.

Moderna London, United Kingdom

On-site Permanent

Associate Director, Resilience Strategic Partnerships – UK

Lead the execution of Moderna’s Long-Term Strategic Partnership with the UK Government, coordinating cross-functional teams across R&D, manufacturing, and access to deliver mRNA-based vaccines. Serve as the primary liaison with senior government stakeholders including UKHSA and DHSC, ensuring delivery of public health commitments through strategic planning, governance, and risk management. Drive program alignment and accountability across complex, interdependent workstreams in a fast-paced, high-impact environment.

Moderna Tameside, SK15 3JG, United Kingdom

On-site Permanent

Facilities Engineering Manager

This role involves providing technical leadership for facility and utility systems at Moderna’s new biotech site in Harwell, Oxford. The Facilities Engineering Manager will oversee maintenance, vendor performance, and engineering projects across R&D and manufacturing environments, ensuring compliance and operational reliability. The position emphasizes continuous improvement, digital tool integration, and collaboration with global teams in a GMP-regulated setting.

Moderna Oxford, United Kingdom

On-site Permanent

Facilities Engineering Manager

This role involves providing technical leadership for facility and utility systems at Moderna’s biotech manufacturing site in Harwell. The Facilities Engineering Manager ensures operational reliability, oversees vendor performance, and drives maintenance excellence across R&D and manufacturing environments. The position emphasizes continuous improvement, compliance, and the use of digital tools including AI-enabled systems, within a GMP-regulated setting.

Moderna

On-site Permanent

Analyst, Quality Control, Microbiology

This role involves performing routine environmental monitoring, water sampling, and microbiological testing (including sterility, bioburden, and endotoxin) for mRNA products in a GMP-regulated manufacturing environment. The analyst will support method transfers, data review, investigations, and compliance activities while working closely with internal teams and contract laboratories. Emphasis is placed on digital workflows, data integrity, and adherence to cGMP standards.

Moderna Oxford, United Kingdom

Associate Director, CMC Regulatory Science, International

Lead the development and execution of CMC regulatory strategies for mRNA-based products across global submissions, including IND/CTA/BLA/MAA filings. Provide expert guidance on regulatory compliance, interact with health authorities, and support quality and manufacturing teams through change controls and submissions. Work within a multidisciplinary team at the Harwell site to advance Moderna’s pipeline in vaccines, oncology, and rare diseases.

Moderna London, United Kingdom

On-site Permanent

Associate Director, Global Regulatory Science, CMC

Leads global regulatory strategy for CMC (Chemistry, Manufacturing, and Controls) in support of mRNA-based medicines, ensuring compliance with international regulations and guiding submissions across multiple therapeutic areas. Works closely with manufacturing, quality, and development teams to prepare high-quality regulatory documentation and engage with health authorities. Focuses on biologics, particularly in vaccines, oncology, and rare diseases, within a rapidly expanding biotech environment.

Moderna London, United Kingdom

Hybrid Permanent