Jobs in Stoke-on-trent

Principal Scientist, Immunogenicity and Ligand Binding Assays

This role involves leading and executing phase-appropriate bioanalytical strategies for immunogenicity and ligand binding assays (LBA) within Moderna’s mRNA-LNP therapeutic pipeline. The Principal Scientist will oversee assay development, validation, and sample analysis, ensuring regulatory compliance and scientific rigor across clinical programs. The position emphasizes collaboration with cross-functional teams, integration of emerging technologies including AI-enabled tools, and contribution to regulatory submissions and data interpretation in a GcLP-compliant environment.

Moderna Oxford, United Kingdom

Hybrid Permanent

Scientist, Genetic Assays

This role involves designing and executing biochemical and molecular biology assays to support pharmacokinetic/pharmacodynamic analysis. Responsibilities include developing robust mRNA-based bioanalytical capabilities, troubleshooting scientific issues, and collaborating with external partners. The position also offers opportunities to work with Generative AI and digital tools to enhance scientific workflows.

Moderna Oxford, United Kingdom

Associate Director, CMC Regulatory Affairs, International

This role involves leading CMC regulatory strategies and submissions for international markets, with a focus on mRNA-based products across vaccines, oncology, and rare diseases. The individual will guide global regulatory compliance, interact with health authorities, and support manufacturing and quality teams through regulatory interpretation and change control. It requires deep expertise in CTD-format filings and a proactive approach to managing multi-therapeutic regulatory programs in a fast-paced environment.

Moderna

On-site Permanent

Scientist, Clinical Biomarker Laboratory, Immuno-Assays - Cell Based

This role involves leading the development, qualification, and execution of complex cell-based immunoassays to support Moderna’s clinical trials across multiple therapeutic areas. The scientist will generate high-quality, regulatory-compliant data using advanced immunological techniques and serve as a subject matter expert within cross-functional teams. Emphasis is placed on innovation, scientific rigor, and integration of emerging technologies including digital and AI-enabled workflows in a GCP/GLP-regulated environment.

Moderna

Hybrid Permanent

Sr. Manager, Site Budgets and Contracts

This role involves leading the creation and management of investigator site budgets and contracts for global clinical trials, using Grants Manager and FMV benchmarking tools. The Senior Manager collaborates with CROs, Legal, and Clinical Operations to ensure site budgets align with study forecasts and are executed on time. Responsibilities include strategic planning, contract negotiation oversight, risk identification, and process improvement within an outsourced trial model.

Moderna

Hybrid Permanent

Principal Scientist, Bioanalytical & Molecular Assays

This role involves leading the development and validation of advanced molecular assays—including RT-qPCR, dPCR, and NGS-based methods—for clinical biomarker programs at Moderna. The scientist will drive end-to-end assay lifecycle management, ensure compliance with GCLP and regulatory standards, and collaborate across multidisciplinary teams to generate high-quality genomic data. A key focus is integrating genomics, bioinformatics, and clinical insights to support drug development and inform future pipeline strategies.

Moderna

Hybrid Permanent

Maintenance Engineering Manager - Packaging

Lead the technical development and implementation of a new labeling and secondary packaging operation at Moderna’s Harwell site, from initial design through commissioning and validation. Establish maintenance strategies, ensure GMP compliance, and drive continuous improvement using engineering excellence principles and digital tools. Build and lead a high-performing engineering team to support long-term operational success in a regulated biotech environment.

Moderna

Hybrid Permanent

(Fixed-Term) Manufacturing Associate I

This role involves operating and maintaining equipment in a cGMP-regulated mRNA vaccine production environment, ensuring safe and compliant manufacturing processes. The associate will execute production operations, support quality assurance, troubleshoot technical issues, and contribute to continuous improvement initiatives. Work is conducted in a highly automated, digitally enabled facility with a focus on operational excellence and innovation in mRNA technology.

Moderna

Facilities Engineering Manager

This role involves providing technical leadership for facility and utility systems at Moderna’s new biotech site in Harwell, Oxford. The Facilities Engineering Manager will oversee maintenance, vendor performance, and engineering projects across R&D and manufacturing environments, ensuring compliance and operational reliability. The position emphasizes continuous improvement, digital tool integration, and collaboration with global teams in a GMP-regulated setting.

Moderna Oxford, United Kingdom

On-site Permanent

Facilities Engineering Manager

This role involves providing technical leadership for facility and utility systems at Moderna’s biotech manufacturing site in Harwell. The Facilities Engineering Manager ensures operational reliability, oversees vendor performance, and drives maintenance excellence across R&D and manufacturing environments. The position emphasizes continuous improvement, compliance, and the use of digital tools including AI-enabled systems, within a GMP-regulated setting.

Moderna

On-site Permanent

Associate Director, Global Regulatory Science, CMC

Leads global regulatory strategy for CMC (Chemistry, Manufacturing, and Controls) in support of mRNA-based medicines, ensuring compliance with international regulations and guiding submissions across multiple therapeutic areas. Works closely with manufacturing, quality, and development teams to prepare high-quality regulatory documentation and engage with health authorities. Focuses on biologics, particularly in vaccines, oncology, and rare diseases, within a rapidly expanding biotech environment.

Moderna London, United Kingdom

Hybrid Permanent

Associate Director, CMC Regulatory Science, International

Lead the development and execution of CMC regulatory strategies for mRNA-based products across global submissions, including IND/CTA/BLA/MAA filings. Provide expert guidance on regulatory compliance, interact with health authorities, and support quality and manufacturing teams through change controls and submissions. Work within a multidisciplinary team at the Harwell site to advance Moderna’s pipeline in vaccines, oncology, and rare diseases.

Moderna London, United Kingdom

On-site Permanent

Analyst, Quality Control, Microbiology

This role involves performing routine environmental monitoring, water sampling, and microbiological testing (including sterility, bioburden, and endotoxin) for mRNA products in a GMP-regulated manufacturing environment. The analyst will support method transfers, data review, investigations, and compliance activities while working closely with internal teams and contract laboratories. Emphasis is placed on digital workflows, data integrity, and adherence to cGMP standards.

Moderna Oxford, United Kingdom

Associate Director, Global Regulatory Science, CMC

This role leads global regulatory CMC strategy for mRNA-based medicines, developing and implementing regulatory plans for international submissions. The individual will guide CMC documentation, interact with health authorities, and provide strategic input across product development stages, ensuring compliance with EU and global regulations. The position plays a key part in advancing Moderna’s pipeline of transformative therapeutics across vaccines, oncology, and rare diseases.

Moderna

Hybrid Permanent

Associate Director, CMC Regulatory Science, International

This role involves leading CMC regulatory strategy for global mRNA product development, preparing and reviewing regulatory submissions, and guiding cross-functional teams on compliance and agency interactions. The position requires deep expertise in biologics CMC regulations, particularly in EU and ROW markets, and plays a key part in shaping regulatory pathways across vaccines, oncology, and rare diseases. Based at the Harwell site, it emphasizes in-office collaboration within a multidisciplinary team.

Moderna

On-site Permanent