Latest Gene Therapies Jobs

Director, Pharmacovigilance

Leads global pharmacovigilance and safety strategy for gene therapy products, overseeing signal management, risk assessment, and benefit-risk profiling across investigational and marketed phases. Provides medical oversight for clinical trials, including safety data review, SAE evaluation, and regulatory submissions. Collaborates cross-functionally to ensure compliance with global safety regulations and supports health authority interactions on product safety matters.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Senior Scientist - ELN & Data Specialist, Global Technical Development

This role involves hands-on administration, configuration, and continuous improvement of an Electronic Lab Notebook (ELN) platform to support R&D and Technical Development laboratories. The scientist will define ELN standards, design workflows and templates, integrate systems, and develop data repositories to enable data-driven decision-making. Collaboration with cross-functional teams is essential to ensure compliance, data integrity, and effective use of the ELN across scientific operations.

Orchard Therapeutics London, United Kingdom

Hybrid Permanent

Senior Clinical Trial Case Manager

This role involves leading safety data review and pharmacovigilance activities within clinical trials, ensuring compliance with international regulations such as GxP. The individual will mentor team members, manage CAPAs, support regulatory inspections, and contribute to safety reporting and risk management. Key responsibilities include MedDRA coding, safety data analysis, and developing pharmacovigilance procedures to support global regulatory requirements.

CSL

On-site Permanent

Senior Director, Search & Evaluation Late TA Lead, Immunology

This role involves leading strategic sourcing and evaluation of late-stage external Hematology therapeutic assets, engaging with key opinion leaders, and integrating innovation into portfolio planning. The position requires deep clinical expertise, a proven track record in deal-making, and strong collaboration with cross-functional teams.

CSL US$263,000 – US$328,000 pa

Hybrid Permanent

Principal Scientist, Bioanalytical & Molecular Assays

This role involves leading the development and validation of advanced molecular assays—including RT-qPCR, dPCR, and NGS-based methods—for clinical biomarker programs at Moderna. The scientist will drive end-to-end assay lifecycle management, ensure compliance with GCLP and regulatory standards, and collaborate across multidisciplinary teams to generate high-quality genomic data. A key focus is integrating genomics, bioinformatics, and clinical insights to support drug development and inform future pipeline strategies.

Moderna

Hybrid Permanent

Principal Scientist, Immunogenicity and Ligand Binding Assays

This role involves leading scientific strategy and execution for immunogenicity and ligand binding assays (LBA) in support of Moderna’s mRNA-LNP therapeutic programs. The Principal Scientist will oversee regulated bioanalytical activities including assay development, validation, and sample analysis, ensuring compliance with GcLP, GLP, and GCP standards. The position plays a key role in clinical development by generating high-quality data to inform regulatory submissions and advance innovative medicines, with opportunities to engage in AI-enabled and digital analytical approaches.

Moderna

Hybrid Permanent

Senior Scientist, R&D

Develops and optimizes metagenomic extraction and sequencing workflows for diverse sample types, focusing on low-biomass and inhibitor-rich matrices. Works end-to-end from DNA/RNA extraction to library prep, with emphasis on high molecular weight recovery and virology applications. Collaborates globally to enhance data quality and scalability for AI-driven biological discovery.

Basecamp Research London, United Kingdom

On-site Permanent

Bioinformatics Scientist

This role involves transforming large-scale, complex biological data—primarily microbiomes—into annotated, model-ready resources for AI-driven discovery. The scientist will develop novel methods to analyse non-standard genomic data, ensure data integrity, and contribute to tools that guide global biodiversity sampling. Work spans prokaryotes and eukaryotes, with a focus on innovation where traditional tools fall short.

Basecamp Research London, United Kingdom

On-site Permanent

Scientist, Cell-Based Screening - Plant Biology Institute

Develop and lead a plant cell-based screening platform to evaluate carbon fixation and photosynthetic efficiency, using suspension cultures and genetic engineering techniques like CRISPR. Identify improved enzyme variants and metabolic pathways, then validate top candidates in whole plants to enhance crop performance. Work within a multidisciplinary team to drive discovery from lab to scalable agricultural solutions, with strong emphasis on IP generation and ethical innovation.

Ellison Institute of Technology Oxford, United Kingdom

On-site Permanent

Genotyping and Event Delivery Manager - Plant Biology Institute

This role leads the molecular confirmation and genotyping of gene-edited and transgenic crop events, ensuring high-quality, data-rich handover to downstream teams. The candidate will establish stage-gate criteria, manage genotyping workflows across multiple technologies, and integrate with transformation, bioinformatics, and trait discovery teams. The position is central to building a scalable, industrial-grade pipeline for crop development in species such as corn and wheat.

Ellison Institute of Technology Oxford, United Kingdom

On-site Permanent