Biotechnology Jobs

• Cambridge, United States
• Hybrid · 3 days in office
• Lead

Lead the safety assessment strategy for small molecule and biologic drug discovery projects from inception to regulatory submission, designing screening cascades and mechanistic experiments. Partner with machine learning researchers to build predictive toxicology models and manage CRO relationships for outsourced wet-lab data generation, while mentoring junior team members.

KNIME · Python

• London
• Hybrid · 3 days in office
• Lead

Owns safety assessment strategy for drug discovery projects from inception to regulatory submission, working with small molecule and biologics platforms. Designs screening cascades, authors IND packages, and manages CRO relationships for outsourced wet-lab work. Also guides development of an AI predictive toxicology platform with ML researchers.

AI/ML · AlphaFold

• London
• Hybrid
• £119,250 – £198,750 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work, applying AI/ML and quantitative systems pharmacology methods, and defends results to governance boards and regulators. Sits within Oncology Translational Medicine's Clinical Pharmacology Modelling and Simulation group, working across small molecules, biologics and antibody drug conjugates.

NONMEM · R

• Belgium-Wavre
• Hybrid
• €119,250 – €198,750 pa
• Director

Leads model-informed drug development for oncology programmes, defining and executing model-based strategies from late candidate selection through life cycle management. Conducts population PK, exposure-response and simulation-based trial design work, applying AI/ML, quantitative systems pharmacology and model-based meta-analysis to small molecules, biologics and antibody drug conjugates. Presents and defends modelling outcomes to governance boards and regulators, and contributes to protocols, analysis plans and submissions.

NONMEM · R

• Oxford
• On-site
• Mid-level
• Contract

Designs and delivers immunogenicity and bioanalytical strategies for regulated clinical programmes, developing ADA, nAb, PK and PD assays using ELISA, MSD and cell culture. Works with multidisciplinary teams to validate assays, manage reagents and SOPs, and integrate digital and AI-enabled tools. Site-based at Harwell within a growing mRNA-focused team.

ELISA · MSD · LIMS +2

• Oxford
• On-site
• Senior

Sole-contributor scientist role developing and executing biochemical and molecular biology assays for PK/PD analysis, spanning genomic DNA/RNA isolation, qPCR, ddPCR, RNA sequencing, MSD, ELISA and immunoblotting. Works within Moderna's Clinical Bioanalytical team at Harwell, Oxfordshire, ensuring GcLP-compliant assay qualification and validation, troubleshooting with external CRO partners, and building internal and external mRNA-based bioanalytical capability.

MSD · LIMS · eLNB +1

• London
• Hybrid
• Lead · manages people

Serves as the clinical trial pharmacy subject matter expert across global oncology programmes, advising on investigational product handling, preparation, storage and accountability, and on hazardous drug and CSTD requirements. Develops pharmacy manuals and training for site pharmacists and study teams, supports audits and CAPAs, and oversees FSP pharmacists and external vendors. Hybrid role spanning London, Paris or Cambridge MA.

Closed System Transfer Devices

• Cambridge
• Hybrid · 3 days in office
• Director · manages people

Owns International regulatory strategy for complex cell therapy programs, embedding regional requirements into evidence generation, submissions and labeling. Leads BLA/MAA planning, Health Authority engagements and labeling negotiations, integrating clinical, CMC, safety and commercial input. Also leads a matrix regulatory team, coaching colleagues and shaping policy and process improvements.

BLA · MAA · IND +2

• London
• Hybrid
• Lead · manages people

Leads one or more Early Development Asset Teams, owning integrated strategy from candidate nomination through first-in-human trials across preclinical, translational, clinical, regulatory and CMC workstreams. Serves as scientific champion for oncology assets, presenting data and investment recommendations to governance bodies and contributing to in-licensing due diligence.

• London
• Hybrid
• Director
• Permanent

Lead clinical pharmacology and pharmacometrics across a growing drug discovery portfolio, serving as the quantitative lead on cross-functional project teams. Apply MIDD, PBPK, population PK/PD and QSP modelling to translate nonclinical data into human dosing and trial design, spanning small molecules, biologics and novel platforms. Also manages CRO partnerships and authors regulatory submissions.

NONMEM · R · Monolix +3

• Stevenage
• Lead

Lead the push for an MHRA MIA(IMP) licence at the first site of an automated CDMO for regenerative medicine, establishing and maintaining a scalable PQS and ensuring production complies with quality policies. The role covers audit leadership, inspection readiness, quality strategy with leadership, and preparing for future commercial batch release, working alongside advisors from Catalent and Resilience.

eQMS · MasterControl · Electronic Batch Records +1

• Edinburgh
• Hybrid · 2–3 days in office
• £31,000 – £36,000 pa
• Mid-level
• Contract

Implement high-throughput plasmid assembly, colony PCR, Minipreps and pathway construction to build strains for hypothesis testing and model training. Work across disciplines in a lab-based, cross-pollinating team, with fortnightly research updates, mentorship and organised labbook/data keeping. Golden Gate assembly, Benchling in silico cloning and DNA sequencing are core.

Benchling · QIAgility

• Oxford
• On-site
• Mid-level
• Permanent

Designs and runs evolution campaigns and selection schemes to optimise photosynthetic proteins, applying genome editing, directed evolution and protein engineering within a stage-gated plant engineering programme. Works in an interdisciplinary team translating photosynthesis, carbon fixation and yield findings into commercial and IP opportunities.

• Oxford
• Hybrid
• Permanent

The role sits within a mission-driven institute translating scientific discovery into real-world impact across health, generative biology, food security, climate and AI. Day-to-day work centres on computational biology research, collaborating with scientists, technologists and policy makers in an interdisciplinary environment.

• New York, United States
• Hybrid · 2–3 days in office
• US$151,800 – US$220,660 pa
• Senior

Integrate phenomics, transcriptomics, genomics and proteomics data to nominate novel targets and validate immunology and inflammation disease biology, piloting new methods for target discovery and early patient population hypotheses. Partner cross-functionally with biologists, chemists, data scientists and engineers to build data packages that drive program milestones and investment decisions.

Python · R · CRISPR