418 jobs for “Operational Excellence”
Provides medical and scientific leadership for pharmacovigilance and risk management of oncology assets in clinical development, interpreting safety data, detecting signals and delivering benefit-risk recommendations. Represents Safety on cross-functional matrix teams and governance committees, and interacts with regulators. Hybrid UK-based role with mentoring and process-improvement duties.
Provides medical and scientific leadership for pharmacovigilance and risk management of oncology assets in clinical development, interpreting safety data, detecting signals and delivering benefit-risk recommendations. Represents Safety on cross-functional clinical matrix teams and governance committees, and may lead Safety Review Teams. Hybrid role based in the UK with global regulatory and partner interaction.
Relation Therapeutics
Processes and quality-controls paired single-cell RNA-seq and scATAC-seq data at scale, building Nextflow pipelines for custom combinatorial indexing chemistries and integrating multimodal datasets for GPU-accelerated model training. Partners with wet lab scientists and ML modellers to design evaluation frameworks and biological benchmarks, bridging experimental and computational teams in a matrixed TechBio environment.
STARsolo · Alevin-fry · Chromap +5
Eurofins
Performs registration, preparation and analysis of samples, reading plates and validating results to required quality standards. Prepares media and QC, maintains records and HSE compliance, and supports continuous improvement and UKAS accreditation. Full-time, 37.5 hours over two shift patterns including weekends.
UKAS · ISO
Leads the full statistical contribution to a clinical development programme, defining statistical strategy for trial design, analysis and regulatory submissions, and representing Biostatistics in interactions with the FDA, EMA and PMDA. Also manages outsourcing to CROs and internal statistical programmers, and supports departmental improvement initiatives.
SAS · R
Acts as case management subject matter expert for assigned clinical trials, overseeing safety reporting plans, vendor performance and ICSR compliance. Leads pharmacovigilance processes, supports GxP inspections and audits, and provides study-specific training to vendors and internal teams. Requires deep PV and regulatory knowledge in a multinational pharmaceutical setting.
Drug Safety Database
Isomorphic Labs · 201–500 people · Series A
Technically lead the Platform group, owning cloud infrastructure and the software lifecycle for training and inference systems. Work across GCP, Kubernetes, Docker and Terraform with scientists and ML researchers, reporting to the Director of Engineering in a small, fast-moving team.
GCP · Kubernetes · Docker +7
Isomorphic Labs · 201–500 people · Series A
Join the Compute Infrastructure team to keep a planet-scale GPU accelerator fleet healthy and efficient. You'll build observability and telemetry pipelines, automate recovery, hunt compute waste, and optimise accelerator utilisation for large-scale training and inference, working closely with ML infrastructure and research teams.
GCP · Kubernetes · Nvidia GPU +1
Join a cross-functional team of scientists, engineers and drug hunters advancing frontier AI research and end-to-end applications across drug discovery, design and translation. Work spans large datasets, multimodal models and virtual cell/virtual patient concepts within one of biopharma's largest AI compute clusters.
AI Compute Clusters
Lead and develop a team of Central Monitors, shaping central and site monitoring strategies across a global development portfolio. Oversee trial-data surveillance, risk reviews and signal detection using Central Monitoring technology, translating complex risk signals into actionable insights for Clinical Trial Teams. Partners with clinical, data and risk-surveillance teams to strengthen risk-based monitoring and Risk-Based Quality Management.
Artificial Intelligence
Parexel
Configures, tests and maintains electronic Clinical Outcome Assessment studies in platforms such as Medidata Designer eCOA, translating protocols and licensed instrument requirements into questionnaires, schedules and branching logic. Acts as technical contact for sponsors and vendors, coordinates eCOA-to-EDC integration and deployment, and mentors less-experienced study designers across multiple global trials.
Medidata Designer eCOA · Medidata Rave
Fortrea
Prepare and handle investigational medicinal products in a cGMP clean room, applying sterile technique and GMP during live first-in-human studies. Work in pairs with Technical Officers on study set-up, dose calculations, batch records and equipment checks, with the clinic and pharmacy under one roof at an MHRA-accredited Phase I unit.
Outlook · Word · Excel +1
Danaher
Leads and coordinates global field action management across Leica Biosystems, including recalls, corrections, removals and Field Safety Corrective Actions. Acts as global process owner and subject matter expert, partnering with Quality, Regulatory, Operations and Commercial teams on investigations, risk assessments and vigilance reporting. Also drives inspection readiness, KPI monitoring and continuous improvement across regions.
EU IVDR · ISO 13485 · FDA +1
Fortrea
Lead early-phase clinical trials as Principal Investigator or Project Physician, taking studies from start-up through closeout and the Clinical Study Report. Work across first-in-human studies, multiple therapeutic areas and an NHS Trust collaboration, with on-call cover and mentoring of less experienced physicians.
MHRA · cGMP · NHS Trust
Bristol Myers Squibb
Owns the clinical strategy for one or more neuropsychiatry programs, serving as Clinical Trial Physician and clinical point of accountability for the Clinical Development Team. Leads trial design, data interpretation, regulatory submissions and health authority interactions, with matrix leadership across global scientific teams.
