Go back Guy's and St Thomas' NHS Foundation Trust
Senior Medical Statistician
The closing date is 27 July 2025
Could you be passionate about making a significant contribution towards ensuring that leukaemia, lymphoma, aplastic anaemia, and immune deficiency disorder patients receive the highest-quality and most effective treatments and care they need to live well?
The British Society of Blood and Marrow Transplantation and Cellular Therapy (BSBMTCT) has an exciting opportunity for an enthusiastic and committed Senior Medical Statistician, who will lead the statistical work of our Society and data registry.
You will provide full statistical support and analysis to meet a range of purposes including research, the statutory reporting of outcomes of stem cell transplants and other cellular therapy treatments, and the meeting of our contractual obligations to commercial partners, which generates income towards the achievement of our mission. As our partnerships become established, we anticipate that you will oversee the work of a small team of statisticians, working across partner organisations. You will work closely with the Trustees, Chief Executive, Head of Registry, data management team, sub-committees, members, investigators and commercial partners.
Our staff are hosted by Guy's and St Thomas' NHS Foundation Trust and enjoy the benefits of being an NHS staff member, whist focusing upon improving patient outcomes - both survival and quality of life - by advancing the fields of blood and marrow transplantation and cellular therapy.
Main duties of the job
You will work with the Trustees, Chief Executive, Head of the Registry, the data management team, Sub-Committees, including the Clinical Trials Sub-Committee (CTSC), individual members, investigators and commercial partners to lead our statistical work and provide full statistical support and analysis to meet a range of purposes including:
research
the statutory reporting of outcomes of stem cell transplants and other cellular therapy treatments
meeting our contractual obligations to commercial partners, generating income for BSBMTCT, for application across the wider BMTCT community
You will work with key investigators involved in complex studies which have been peer reviewed and approved by the BSBMTCT CTSC. Close liaison with the Co-Chairs of the BSBMTCT CTSC, and the Head of the BSBMTCT Data Registry will be required.
You will be required to review all study proposals from the outset and, in liaison with the Head of the BSBMTCT Data Registry, advise on feasibility of any protocols submitted for review.
This role will, in time, supervise a small team of statisticians and data analysts/scientists, working directly or within one or more partners. The BSBMTCT team works with a wide range of medical professionals across the country and in Ireland and collaborates with clinicians across Europe and the world.
About us
The British Society of Blood and Marrow Transplantation and Cellular Therapy (BSBMTCT) is the professional society for bone marrow/stem cell transplant centres in the UK & RoI. We have 49 NHS and private member centres contributing data to the registry. The BSBMTCT Registry was established in March 2001 and is the UK Subset of the European Registry for Blood and Marrow Transplantation (EBMT).
Ourpurposeis to improve patient outcomes - both survival and quality of life - by advancing the fields of blood and marrow transplantation and cellular therapy.
We strive for a worldwhere all transplant and cellular therapy patients receive the highest-quality and most effective treatments and care they need to live well. This is ourvision.
OurMissionis to:
- Serve as the representativevoice and advocate.
- Maintain aregistryof all stem cell transplants and cellular therapies in the UK and RoI, and provide data and insight to inform research, commissioning, policy and clinical practice.
- Undertake, facilitate and contribute to pioneeringresearch and clinical trialsthat improve the outcomes of treatment and care.
- Provideeducation and trainingto transplantation and cellular therapy professionals, promotinh the sharing ofknowledge and good practice.
- Developguidelines, protocols and quality standards
- Providedata and insightto patients and the public, to educate and empower them as they make decisions about their treatment and care.
Job responsibilities
Provide effective leadership and specialist statistical expertise to the wide-ranging work of the British Society of Blood and Marrow Transplantation and Cellular Therapy (BSBMTCT).
Facilitate research from accrued study data, undertaking the required data analyses with a view to publication in peer reviewed scientific journals.
Project manage statistical research projects and other BSBMTCT projects as required to meet BSBMTCTs business plan and other key work objectives.
Oversee the provision of feasibility reviews on potential new studies, both retrospective and prospective, being proposed by the BSBMTCT CTSC, including the recommendation of appropriate cohort sizes and structures of studies, so as to maximise their scientific integrity.
Assist with the reporting of studies and writing of papers for publication in peer reviewed, nationally and internationally read journals, with emphasis on the statistical aspects of such papers.
Communicate statistical/analytical/epidemiological matters clearly to data managers, statisticians, clinicians, nurses. other allied health professions and very senior colleagues.
Provide, receive, interpret and communicate very complex information in a way that is easily understandable and carries people along with you.
Communicate effectively the results of complex analyses to a range of stakeholders including individuals, and small and large groups.
Collaborate with national and international registries and bodies (especially NHSE and the other national NHS bodies) and international and global bodies such as CAN/UK/ANZ (partnership between Canada, Australia, New Zealand, and the UK) and EBMT, the European Group for Blood and Marrow Transplantation, based in Leiden and Barcelona.
Responsibility for effective line management and support, including assigning responsibility for individual tasks, providing day to day support and balancing the workloads of individuals, appraisal, staff development, staff motivation, work plans, training and supervision of other staff as required.
Management and co-ordination of work flow with Statisticians who work on our behalf for external organisations.
Responsible for engaging with pharmaceutical companies and other commercial partners to understand their requirements and deliver against agreed contracts.
Person SpecificationQualifications
- Degree or equivalent level qualification in Statistics/Mathematical or Biomedical Sciences or an allied subject (including health care disciplines)
- Masters level qualification in medical statistics, applied statistics or in a related healthcare/mathematical discipline
Experience
- Extensive operational experience in highly complex statistical analysis in a clinical environment
- Experience of using statistical methods and the essential preparation required to ensure clean data prior to conducting any analyses
- Experience of working with large sets of very large and highly complex data
- Experience of providing, receiving and interpreting very complex and contentious information
Skills/Knowledge
- Familiarity with the use of database tools to input, generate reports and analyse the data
- Proficient user of MS Word, Excel, PowerPoint and e-mail, and a willingness to learn new systems/familiarity with Stata or SPSS or R
- Excellent interpersonal skills to facilitate liaison with colleagues and study collaborators across the UK and Republic of Ireland
- Evidence of an awareness of statistical thinking, techniques, and current literature
- Able to analyse highly complex data, compare possible interpretations of the data and present a judgement of the correct interpretation
- Able to plan and organise workload on multiple and competing studies and to meet deadlines for submission of abstracts for conferences, revision of manuscripts for journals, and other external presentations
- Ability to advise on the planning of studies - both ongoing and proposed and to explain statistical concepts and findings to all levels of audience
- Ability to recommend cohort size, structure and data collection requirements of studies
General
- Recognise ethical and legal issues involved when dealing with and safeguarding confidential patient data
- Willingness to travel to attend meetings and conferences
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Guy's and St Thomas' NHS Foundation Trust
Address
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