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For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.
Job Summary
Are you a skilled formulator looking to take the next step in your career?
Have you got experience of working in an industrial R&D setting, developing formulations for novel small molecule API’s?
Do you want to join a global contract research organisation that improves health and lives?
Our expanding pharmaceutical development team in Harlow, Essex are recruiting for an experienced formulation scientist. In this role you will apply formulation expertise to guide formulation projects through pre-clinical development.
This leadership role in a small but far-reaching team is an excellent opportunity to help shape the future direction of the Pharmaceutical Development group at Charles River. You will have the opportunity to work on a variety of client projects spanning oral, inhaled, dermal and parenteral administration routes. This role encompasses project management and ownership of client relationships, as well as supporting lab work when required.
Main Tasks
- Advise as a subject matter expert for Integrated Drug Discovery and Development projects, guiding formulation strategy to ensure successful outcomes.
- Design and execute formulation study plans, based on client needs.
- Manage client formulation projects to agreed timelines and budgets.
- Act as the scientific point of contact for clients, from initial discussion through to project delivery.
- Mentor junior scientists in formulation techniques and strategies.
Skills And Experience
The ideal candidate has a pro-active can-do approach, pays attention to detail, and has the ability to adapt to changing demands and requirements. They use PK data and the Developability Classification System to drive formulation strategy and is comfortable communicating complex scientific data to stakeholders with varying degrees of expertise.
A working knowledge of solid form characterisations techniques, non-oral dosage routes and formulation of “Beyond Rule of 5” compounds is desirable. Experience of scientific project management would also be advantageous.
- Minimum BSc. Qualification in a relevant subject (Chemistry, Pharmaceutical Sciences or related subject). Post-graduate qualifications desirable.
- Extensive experience of working in an industrial R&D setting, developing formulations for novel small molecule APIs.
- Strong knowledge of the drug discovery and development process.
- Experience of mentoring junior colleagues.
- Experience in designing and executing preformulation studies, including:- Physicochemical assessment, Solubility Assessment and Biorelevant Dissolution studies.
- Expertise in at least one of the following enabling oral formulation techniques:- Spray Drying, Wet milling for particle size reduction or Emulsion development.
What We Offer You
- A very comprehensive benefits package from day one, including a generous pension contribution, and flexible health benefits.
- Parental leave.
- Group Life Assurance and Group Income Protection.
- Remote GP access 24/7.
- Wellbeing support and initiatives.
- Access to great discounts via our CREDS discount scheme.
- Global opportunities and strong career progression.
- The chance to work on several varied projects and liaise globally and nationally with other business areas.
- To be able make a difference to health and wellbeing of people.
- To continue your own career growth.
- Cycle to work scheme and much much more!
About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.
226151Seniority level
- Seniority levelMid-Senior level
Employment type
Job function
- Job functionScience
- IndustriesAutomation Machinery Manufacturing
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