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Scientist- Tissue Profiling 12 month Contract

Hlx Life Sciences
Slough
3 days ago
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Job Title:

Scientist – Tissue Handling

Employment Type:12 month Contract

Location:London, UK - 100% Lab based


The Role:

We are seeking ahighly motivated Scientist/ Recent Ph.D Graduate with a background in Molecular Biology, Cell Biology, or a related field. The ideal candidate will have experience in spatial transcriptomics and proteomics, particularly usingFFPE tissue samples, and a strong background in10X Genomics library preparationfor NGS.

You’ll work in a fast-paced, collaborative environment, driving the development and optimization of cutting-edge spatial omics workflows in support of translational research and clinical discovery.


Key Responsibilities:

  • Design, execute, and troubleshoot experiments using10X Genomics Visiumand related platforms for spatial transcriptomics.
  • Process and analyzeFFPE and fresh frozen tissue samplesfor transcriptomic and proteomic profiling.
  • Prepare high-quality NGS libraries forIllumina sequencing, ensuring data integrity and reproducibility.
  • Optimize protocols and workflows for challenging tissues (e.g.,fibrotic, adipose, cartilage, bone).
  • Collaborate with bioinformaticians, pathologists, and clinical researchers to interpret spatial omics data.
  • Maintain accurate records, contribute to publications, and present findings at internal and external meetings.

Required Qualifications:

  • Ph.D. in Molecular Biology, Cell Biology, Biotechnology, or related discipline with a focus onspatial transcriptomics or proteomics.
  • Proven experience handlingFFPE tissuesfor transcriptomic and protein-based methods.
  • Expertise in10X Genomicslibrary preparation and workflows forNGS(e.g., Chromium, Visium).
  • Familiarity withIllumina sequencing platformsand general NGS QC metrics.
  • Experience working with difficult tissue types such asfibrotic, adipose, cartilage, or bone.
  • Hands-on experience insingle-cell technologies(e.g., scRNA-seq, CITE-seq) is a strong plus.

Preferred Skills:

  • Strong understanding of tissue processing, histology, and immunostaining techniques.
  • Excellent organizational and communication skills.
  • Ability to work both independently and within cross-functional teams.

What We Offer:

  • Competitive salary and benefits package.
  • Access to state-of-the-art facilities and research platforms.
  • Opportunities for professional development and international collaboration.
  • A dynamic and inclusive working environment that supports innovation and curiosity.

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