Scientist- Tissue Profiling 12 month Contract...

Job Description

Job Title:

Scientist – Tissue Handling

Employment Type: 12 month Contract

Location: London, UK - 100% Lab based

The Role:

We are seeking a highly motivated Scientist / Recent Ph.D Graduate with a background in Molecular Biology, Cell Biology, or a related field. The ideal candidate will have experience in spatial transcriptomics and proteomics, particularly using FFPE tissue samples, and a strong background in 10X Genomics library preparation for NGS.

You’ll work in a fast-paced, collaborative environment, driving the development and optimization of cutting-edge spatial omics workflows in support of translational research and clinical discovery.

Key Responsibilities:

• Design, execute, and troubleshoot experiments using 10X Genomics Visium and related platforms for spatial transcriptomics.
  
• Process and analyze FFPE and fresh frozen tissue samples for transcriptomic and proteomic profiling.
  
• Prepare high-quality NGS libraries for Illumina sequencing, ensuring data integrity and reproducibility.
  
• Optimize protocols and workflows for challenging tissues (e.g., fibrotic, adipose, cartilage, bone).
  
• Collaborate with bioinformaticians, pathologists, and clinical researchers to interpret spatial omics data.
  
• Maintain accurate records, contribute to publications, and present findings at internal and external meetings.
  
  Required Qualifications:
  
  
• Ph.D. in Molecular Biology, Cell Biology, Biotechnology, or related discipline with a focus on spatial transcriptomics or proteomics.
  
• Proven experience handling FFPE tissues for transcriptomic and protein-based methods.
  
• Expertise in 10X Genomics library preparation and workflows for NGS (e.g., Chromium, Visium).
  
• Familiarity with Illumina sequencing platforms and general NGS QC metrics.
  
• Experience working with difficult tissue types such as fibrotic, adipose, cartilage, or bone.
  
• Hands-on experience in single-cell technologies (e.g., scRNA-seq, CITE-seq) is a strong plus.
  
  Preferred Skills:
  
  
• Strong understanding of tissue processing, histology, and immunostaining techniques.
  
• Excellent organizational and communication skills.
  
• Ability to work both independently and within cross-functional teams.
  
  What We Offer:
  
  
• Competitive salary and benefits package.
  
• Access to state-of-the-art facilities and research platforms.
  
• Opportunities for professional development and international collaboration.
  
• A dynamic and inclusive working environment that supports innovation and curiosity.