Your mission

This is an exciting fully lab-based role in which we are looking for a scientist with an immuno-oncology and pharmacology background. This role entails utilising innovative ideas for assay development to identify pathway biology of novel drug targets. Making use of a wide range of cellular, immunological, biochemical, molecular biology and functional genomic approaches, such as CRISPR/Cas9, you will validate drug targets and novel therapeutic agents including ADC’s.

Key Responsibilities:

• Design and perform experiments aimed at oncology and fibrosis target discovery and validation.
• Contribute to ongoing research on oncology and fibrosis drug discovery projects.
• Establish different robust cell-based assays aimed at target discovery, MOA validation and drug screening.
• Establish and maintain mono and co-cultures of primary cells and cell lines.
• Independently analyse, interpret, report and present results.

Your profile

Key Experience:

• Practical experience in cancer biology, immunology and pharmacology.
• Demonstrable experience in assay development, immuno-oncology and cell death biology.
• Expertise in establishing multi-colour FACS panels for analysis of complex cell populations is an advantage.
• Hands-on experience of key immunological and molecular biology techniques including but not limited to RNA/DNA extraction, qRT-PCR, ELISA/Luminex/MSD, western blotting.
• Prior working experience in the biotech/pharma industry performing laboratory research would be an advantage.

Qualifications and Competencies:

• PhD in Biomedical sciences, Immunology, Biochemistry, Biotechnology or related discipline or MSc plus 3 years practical experience in cellular or molecular biology, molecular pharmacology or cancer biology with a focus on immuno-oncology.
• Prior working experience in the biotech/pharma industry performing laboratory research would be an advantage.
• Able to plan, execute and critically assess experiments independently.
• Excellent time-management skills and ability to work to set deadlines.
• Work well within a team and in a matrix environment.

Why us?

• The potential to enable cutting edge research into the development of new therapies
• An opportunity to work with a diverse team in a fast paced and ambitious environment
• State of the art offices and laboratories at the Westworks, White City
• Highly competitive reward package including private medical insurance, bonus, pension, and much more!

About us