Research Associate in structural biology of bacterial secretion systems

Imperial College London
London
1 month ago
Applications closed

Related Jobs

View all jobs

BRF GeMS Research Scientist

Senior Director Global Business Development Operations

Oncology Pharmacist

Research Associate

Research Technician - Analytical Development

Senior / Lead Clinical Research Associate

We are seeking to recruit an enthusiastic and motivated structural biologist to join the group of Dr Harry Low, Department of Infectious Disease (). The research project focuses on determining the molecular mechanism of bacterial secretion systems including the Tad and Type 4 pilus systems. The position is funded by a long-term Wellcome Trust Discovery award.


You will be leading your own project working from initial clones through to protein purification, structure determination and biochemical/biophysical mechanistic dissection. You will be working on challenging multi-component membrane complexes both in-vitro and in-cell. Specific methodology will include a range of structural biology techniques including cryo-electron microscopy (SPA and tomography), and TIRF microscopy combined with single molecule FRET to probe protein dynamics.


You will have a PhD in structural biology, either cryo-EM, X-ray crystallography or NMR.

*Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £43,003 - £46,297 per annum

Experience in the design and execution of workflow for structure determination of proteins, from molecular biology/biochemical experiments (. DNA cloning and mutagenesis, protein purification) through to structural data collection, processing and model building is expected. Experience in cryo-EM workflows including sample preparation, data collection and processing is essential. Experience in light microscopy studies is desirable. You must have a strong research track record demonstrated by at least one first author publication in an international journal or bioRxiv.


An inclusive, friendly but ambitious lab environment that aims to support you in your mission to make important discoveries and generate world class publications.A well-funded lab underpinned by world class facilities.Opportunities to attend national and international conferences to showcase your work and grow your academic network.The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity.Grow your career: gain access to Imperial’s sector-leading as well as opportunities for promotion and progression. Sector-leading salary and remuneration package (including 39 days off a year and generous pension schemes). Be part of a diverse, inclusive and collaborative work culture with various and resources to support your personal and professional .

Get the latest insights and jobs direct. Sign up for our newsletter.

By subscribing you agree to our privacy policy and terms of service.

Industry Insights

Discover insightful articles, industry insights, expert tips, and curated resources.

Jobs

Portfolio Projects That Get You Hired for Biotech Jobs (With Real GitHub Examples)

Biotechnology is at the forefront of numerous scientific breakthroughs—from vaccine development to CRISPR-based gene editing—and data-driven methods now power much of the innovation in this space. If you’re aspiring to land a role in biotech—be it in drug discovery, genomics, immunology, or computational biology—an impressive portfolio can help you stand out in a fiercely competitive market. But what makes a biotech portfolio compelling? How can you prove your worth to a hiring manager who wants practical, hands-on skills in computational biology, wet-lab data analysis, or next-generation sequencing (NGS)? In this guide, we’ll explore: Why a biotech portfolio is essential for showcasing relevant skills. How to choose portfolio projects that align with emerging biotech roles. Real GitHub examples of projects that demonstrate an end-to-end approach. Tangible project ideas specific to biotechnology. Best practices for organising and presenting your work so that potential employers see your talents at a glance. By the end, you’ll have concrete steps to create a portfolio that highlights your value to recruiters and biotech companies. And, when you’re ready to take the next step, remember to upload your CV on BiotechnologyJobs.co.uk for direct exposure to employers who need your expertise.

Jobs Careers

Biotech Job Interview Warm‑Up: 30 Real R&D & Project‑Design Questions

The biotechnology sector is at the forefront of scientific innovation—encompassing everything from drug discovery and gene editing to agricultural improvements and environmental sustainability. It’s a field that combines cutting-edge research, regulated processes, and commercial acumen. As such, biotech job interviews can be both exciting and rigorous, often spanning technical, operational, and strategic discussions. If you’re gearing up for a biotech interview, be prepared for questions that dive into cell and molecular biology, bioinformatics, clinical trials, manufacturing regulations, and even data analysis. Beyond scientific expertise, recruiters are keen to see how you handle project planning, regulatory compliance, and cross-functional collaboration—especially if the position involves leadership or project management elements. Whether you’re seeking a lab-based R&D role, a regulatory affairs position, or a biotech project management opportunity, thorough preparation is essential. In this article, we’ll explore 30 real interview questions commonly asked in the biotech sector. By reviewing these questions and thinking through your responses, you’ll develop the confidence and clarity you need to showcase your talents effectively. For those looking for the latest biotech opportunities, head to www.biotechnologyjobs.co.uk. It’s a centralised place to discover exciting roles within the UK biotech landscape—covering everything from start-ups to large pharmaceutical companies. Let’s dive in and get you interview-ready.

Jobs

Negotiating Your Biotech Job Offer: Equity, Bonuses & Perks Explained

How to Secure a Compensation Package That Reflects Your True Value in the UK’s Thriving Life Sciences Sector Introduction Biotechnology is one of the most dynamic and impactful sectors in today’s global economy—particularly in the UK, which boasts a thriving research ecosystem and a burgeoning community of innovative start-ups. From cutting-edge work on gene editing and CAR-T therapy to breakthroughs in diagnostics and personalised medicine, the biotech field promises vast opportunities for mid‑senior professionals to make a meaningful difference. However, with these opportunities comes the need for careful negotiation when evaluating a new role. Biotech companies—whether they’re large pharmaceutical giants or lean start-ups—often structure compensation packages that go far beyond simple salaries. These may include equity grants, performance-based bonuses, and a range of perks designed to attract top talent in a competitive market. Focusing solely on your base salary could mean missing out on substantial long-term rewards or lifestyle benefits. In biotech, your contributions might directly influence life-changing products, high-stakes clinical trials, or novel therapeutic approaches. Hence, your compensation should reflect both the immediate and future value you bring. This article aims to be your comprehensive guide to negotiating a biotech job offer in the UK. We’ll delve into why negotiation goes beyond salary, how equity functions in the biotech context, and how performance bonuses and other perks can amplify the overall value of your compensation. Geared for mid‑senior professionals, this guide offers actionable insights to help you secure a holistic compensation package that aligns with your expertise, future goals, and the impact you will have on advancing life sciences.

🍪 We use cookies to enhance your browsing experience on our website. By continuing to use this site, you consent to the use of cookies as described in our Cookie Policy. You can review our Cookie Policy for more information.