Research Associate in Computational Modelling of Neuronal Dynamics - Strand, London, WC2R 2LS...

Job Description

Research Associate in Computational Modelling of Neuronal Dynamics - Strand, London, WC2R 2LSAbout usThe School of Neuroscience is UK’s 2nd largest Neuroscience school with over 500 researchers and 200 PhD students. It is one of three schools at the Institute of Psychiatry, Psychology & Neuroscience. CDN is one of four departments in the School of Neuroscience at the Institute of Psychiatry, Psychology & Neuroscience and is located at Guy’s campus. Researchers have access to support facilities in genotyping, molecular biology and Drosophila work.

CDN has close partnership with the Medical Research Council (MRC) and CDN researchers, together with clinical researchers from King’s, make up the MRC Centre for Neurodevelopmental Disorders. At the Centre for Developmental Neurobiology (CDN), we investigate the mechanisms governing the formation of the brain during embryonic development and in early postnatal life. This is based on the understanding that early experience shapes the way our brain is constructed. While the “ground plan” of the brain is genetically determined, it is also influenced by environmental experience.

We are still far from a complete understanding of how these processes work.About the roleWe are seeking two motivated postdoctoral researchers to join our team working on an exciting Wellcome Trust-funded project. The research focuses on investigating how altering neuronal dynamics affects brain function and dysfunction through computational modelling of neural circuits. What you would be doing:Develop computational models of neural circuits with varied architectures, such as the primary visual cortex and prefrontal cortex, and olfactory bulb and piriform cortexUse these models to interpret experimental results from neural circuit perturbationsInvestigate the effects of altering neuronal dynamics on brain function and dysfunctionAnalysis of simulated or real population unit data in different states from different recordings (e.g. Neuropixels), and build an understanding of how stimulation could move the network between different neural statesCollaborate with team members and experimental partnersPublish findings in peer-reviewed journals and present at conferencesThis is a full time (35 Hours per week) post, on a fixed term contract until the 31st August 2027.