Metabolomics Bioinformatician

Company Description

Syngenta Crop Protection is a leader in agricultural innovation, bringing breakthrough technologies and solutions that enable farmers to grow productively and sustainably. We offer a leading portfolio of crop protection solutions for plant and soil health, as well as digital solutions that transform the decision-making capabilities of farmers. Our 17,900 employees serve to advance agriculture in more than 90 countries around the world. Syngenta Crop Protection is headquartered in Basel, Switzerland, and is part of the Syngenta Group.

Our employees reflect the diversity of our customers, the markets where we operate and the communities which we serve. No matter what your position, you will have a vital role in safely feeding the world and taking care of our planet. Join us and help shape the future of agriculture!

Job Description

We have an exciting opportunity for a Metabolomics Bioinformatician to help drive the invention of safe and sustainable active ingredients in Product Safety by contributing to the cutting-edge research and development within our dynamic and highly talented team. Key responsibilities will include:

• Performing metabolomics data processing, analysis and interpretation with a primary focus on toxicology.
• Seeking out the latest developments in data analysis, in consultation with senior technical experts, assessing their potential use to support projects.
• Developing and maintaining data handling and data retrieval solutions, while representing metabolomics in digital infrastructure projects.
• Contributing to the development of multi-omics integration solutions in multi-disciplinary project teams.
• Communicating the output of metabolomics datasets to a wide and varied community of end users.
• Working with contract organisations and/or academic collaborators to define and develop solutions/tools/workflows to support Syngenta scientists.
• Supporting data generation when required.
• Networking within Syngenta and the external bioinformatics community to ensure best use of resources and opportunities.

Qualifications

What we are looking for?

• Educated to degree level or higher (MSc or PhD) and preferably with post-graduate experience in metabolomics, biochemistry, toxicology or similar.
• In-depth metabolomics experience, including
  • sample preparation, quality control procedures and analytical chemistry on data processing requirements.
  • processing of metabolomics data using specialist software (vendor or open source).
  • bioinformatics and pipeline development skills in e.g. KNIME, R and Python.
  • peak picking, peak annotation, data normalisation and filtering techniques.
  • experienced in multivariate statistics, differentially abundant metabolite selection and pathway analysis.
• Good level of biochemistry knowledge.
• High level of attention to detail and compliance.
• Ability to present complex results to non-specialists in a clear and concise manner.
• Self-motivated learner adept at building relationships.

Desirable skills and experience

• Experience with Thermo Orbitrap MS and software: Xcalibur, Freestyle, Tracefinder, Compound Discoverer, LipidSearch.
• Experience with multiple application areas of metabolomics (in vitro, plant, environmental, mammalian, human etc).
• Biologically contextualising metabolomics results.
• Familiarity with multi-omics data integration.
• Ability to deliver technical leadership in defined areas.

Additional Information

Our site

Jealott's Hill International Research Centre UK is situated in pleasant semi-rural surroundings between Bracknell and Maidenhead and is the place of work for approximately 800 Syngenta scientists and support staff. Jealott's Hill is one of the main global research and development sites and key activities include research into discovery of new active ingredients, new formulation technologies, product safety and technical support of our product range.

What we offer

• Extensive benefits package including a generous pension scheme, bonus scheme, private medical & life insurance.
• Up to 31.5 days annual holiday.
• Campus environment.
• A position which contributes to valuable and impactful work in a stimulating and international environment.
• The chance to work with and learn from highly qualified and experienced employees.
• Learning culture and wide range of training options.

Syngenta has been ranked as atop 5 employerand number 1 in agriculture by Science Journal.

Syngenta is an Equal Opportunity Employer and does not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Learn more about our D&I initiatives here:https://www.syngenta.com/careers/working-syngenta/diversity-and-inclusion

Jealott's Hill has Disability Confident certification.

We are committed to making all stages of our recruitment process accessible to all candidates and our Jealott's Hill site are a Disability Confident Level 2 Employer. Please let us know if you need any assistance or reasonable adjustments throughout your application and we will do everything we can to support you.
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