Engineer the Quantum RevolutionYour expertise can help us shape the future of quantum computing at Oxford Ionics.

View Open Roles

Medicinal Chemist

Genome Therapeutics
Cambridge
3 weeks ago
Create job alert

Job Summary/Experience:

Genome Therapeutics Ltd (GTx) is seeking a medicinal chemist with experience in pre-clinical drug discovery to drive the development of novel therapeutics that target G-quadruplex structures. The ideal candidate will manage outsourced drug discovery activities and play a key role in the design and synthesis of lead compounds, applying a comprehensive understanding of medicinal chemistry principles across internal programmes from hit-to-lead through to candidate nomination.


GTx is a fast paced multidisciplinary company, offering training and experience in genomics, computational biology, drug discovery and clinical studies.


Location: This is an on-site position based at the GTx labs in Cambridge UK.

 

Key Responsibilities

  • Leverage expertise in organic and medicinal chemistry to design and synthesise novel small molecules across multiple programmes and chemotypes
  • Monitor and interpret biological, ADME/PK, and physicochemical property data to propose and execute innovative strategies for improving key drug attributes
  •  Manage multiple CRO relationships, providing synthetic and medicinal chemistry expertise and guidance, and driving productivity and deliverables
  • Provide regular updates on project results both internally and externally
  • Effective written communication, including responsibility for drafting and maintaining patent applications and scientific publications
  • Meticulous record-keeping and strong data organisation using commercial data management systems and electronic notebooks

 

Essential Skills/Experience:

  • PhD in synthetic organic chemistry with >5 years industry experience within pharma/biotech
  • Exposure to medicinal chemistry programmes from hit identification through to candidate nomination
  • Understanding of the multi-parameter optimisation process and ability to integrate disease biology, ADME/PK and toxicology data to solve complex drug discovery problems.
  • Management of outsourced drug discovery projects

 

Desirable Skills/Experience:

  • Prior experience of drug discovery programmes in the field of oncology
  • Knowledge of in silico tools to aid drug design

Related Jobs

View all jobs

IOI Research Assistant - Biochemistry

Analytical Chemist

Medical Laboratory Assistant -Biochemistry department B3

Medical Laboratory Assistant -Biochemistry department B3

QA Specialist - batch release

HPLC Scientist, Medical Devices

Subscribe to Future Tech Insights for the latest jobs & insights, direct to your inbox.

By subscribing, you agree to our privacy policy and terms of service.

Industry Insights

Discover insightful articles, industry insights, expert tips, and curated resources.

Pre-Employment Checks for Biotechnology Jobs: DBS, References & Right-to-Work and more Explained

The biotechnology sector in the UK continues to flourish as one of the world's leading life sciences hubs, with companies ranging from cutting-edge gene therapy startups to established pharmaceutical giants seeking talented professionals. However, securing a position in this highly regulated and security-conscious industry involves comprehensive pre-employment screening that goes far beyond typical recruitment processes. Whether you're a research scientist, bioprocess engineer, regulatory affairs specialist, or clinical trial manager, understanding the extensive vetting requirements is essential for successfully navigating your career in biotechnology. This comprehensive guide explores the various background checks and screening processes you'll encounter when applying for biotech positions in the UK, from basic eligibility verification to stringent security and regulatory compliance assessments.

Why Now Is the Perfect Time to Launch Your Career in Biotechnology: The UK's Life Sciences Renaissance

The United Kingdom stands at the precipice of a biotechnology revolution that promises to reshape medicine, agriculture, manufacturing, and environmental sustainability for generations to come. From the gene therapy pioneers in Oxford to the synthetic biology innovators in Cambridge, Britain's biotech sector is experiencing unprecedented growth, creating extraordinary opportunities for career changers and new graduates alike. If you've been contemplating a move into biotechnology, the stars have never been more perfectly aligned. The convergence of scientific breakthroughs, government investment, industry expansion, and societal need has created a career landscape rich with possibility and purpose.

Automate Your Biotech Jobs Search: Using ChatGPT, RSS & Alerts to Save Hours Each Week

Hunting for biotech roles can feel like a full-time job—new postings drop daily across company career sites, CROs & CDMOs, universities, & general job boards. The good news: you can automate the noisy bits. With a smart mix of keyword-rich alerts, RSS feeds, & a reusable ChatGPT workflow, you’ll bring the right roles to you, triage them in minutes, & tailor applications faster—without missing hidden gems. This guide is your copy-paste playbook for www.biotechnologyjobs.co.uk readers. It’s UK-centric, SEO-friendly, & packed with Boolean strings, prompts, & processes you can set up today. What You’ll Have Working In 30 Minutes A biotech keyword map covering wet lab, bioprocess, QA/QC, regulatory & clinical, plus computational biology/bioinformatics. Shareable Boolean search strings you can paste into Google & job boards to cut noise. Always-on alerts & RSS feeds delivering fresh roles to your inbox or reader. A ChatGPT “Job Scout” prompt that deduplicates listings, ranks fit, & outputs tailored actions. A simple pipeline tracker so you never lose track of deadlines or follow-ups.