We are establishing a cutting-edge Kilo Lab facility and are seeking an experienced Process Development & Scale-Up Manager to lead the way! If you are a skilled chemist or chemical engineer with a passion for process optimization, scale-up and innovation, this is your opportunity to make a real impact.
Experience, qualification, and soft skills, have you got everything required to succeed in this opportunity Find out below.
In this hands-on leadership role, you will be at the forefront of scaling up robust, cost-efficient, and safe chemical processes from laboratory to kilo lab scale (up to 60 litres). You will drive process development, technology transfer, and continuous improvement, ensuring smooth transitions from synthetic labs to production.
This role offers a dynamic, collaborative, and fast-paced environment, where you will lead a talented team, oversee safety and compliance, and shape the future of our kilo lab operations. If you're looking for a challenging and rewarding opportunity in process development, we want to hear from you!
Key Responsibilities
- Responsibility, supervision and monitoring of all development processes within laboratory
- Planning and scheduling coordination of process development in collaboration with other departments and project manager(s)
- Hands-on Scale-up of robust, cost-efficient and safe processes from laboratory to ‘kilo lab’ scale (up to 60 litres)
- Coordinate the development of processes for tech transfer from Synthetic labs to ‘Kilolab’ or Staad production site.
- Overseeing of EHS within the ‘Kilo Lab’ laboratory whilst maintaining a high standard of order and cleanliness
- Ascertain the required Safety Risk assessments for scale up processes and the potential impact
- Documentation of the work in ELNs, Batch Records, reports and transfer protocols
- Organising the ordering of project chemical requirements
- Review and recommend new potential equipment or technology for ‘Continuous Improvement Incentive’
- Recruitment and career development of direct reports
- Fostering a supportive culture among R&D teams and process development teams across Biosynth
Essential Candidate Requirements
- MSc or PhD in Organic Chemistry, Chemical Engineering, or related field
- Extensive previous experience in chemical process development and scale-up roles within the pharmaceutical, chemical, CDMO or related industries
- Experience leading and supporting employees in a process development setting
- Experienced in the design, development and optimisation of chemistry routes and processes for the scale-up of novel Products, API’s, intermediates and raw materials
- Experienced in the handling of hazardous chemistry on scale in the ‘Kilolab’ (e.g. inert transfer of flammable solvents & pyrophoric reagents, dealing with release of highly flammable gases etc.)
- Mastered the use of different isolation/purification techniques such as crystallization, distillation, (automated) column chromatography (normal/reverse phase).
- Experience in transferring upscaled processes to production and providing ongoing support to production teams
- Familiarity with process development planning, equipment maintenance, and safety regulations in a chemical manufacturing environment
- Ability to troubleshoot equipment issues and initiate maintenance tasks to ensure operational efficiency
- Strong problem-solving skills and the ability to troubleshoot process issues during scale-up
- Attention to detail and a commitment to ensuring robust, cost-efficient, and safe processes
- Strong organizational and communication skills to coordinate shift operations and liaise with other departments
- Leadership qualities and the ability to motivate and inspire employees to achieve production goals
- Commitment to safety and cleanliness in the production environment, including adherence to standard operating procedures (SOPs).
Desirable Candidate Requirements
- Previous experience in a leadership or supervisory role within a kilo lab environment
- Familiarity with risk assessment techniques, safety protocols, and regulatory requirements for chemical processes
- Experience with technology transfer processes and documentation requirements for production-scale implementation
- Knowledge of production equipment operation and troubleshooting techniques to address chemical issues during production
- Knowledge of SAP and QMS systems
- Ability to effectively convey technical information to non-technical stakeholders and decision-makers
- Hands-on attitude and positive mindset (“play to win”).
- Resilient when faced by challenges and resistant to time pressure.
You will need your own transport to be able to get to our site.
About us
Biosynth® is an innovative life sciences reagents, custom synthesis and manufacturing services company headquartered in Staad, Switzerland. We are by scientists, for scientists, securing supply chains with consistent quality, across the globe. As a trusted supplier, manufacturer and partner to the pharmaceutical, life science and diagnostic industries, as well as food, agrochemical and cosmetic customers, we have facilities on three continents and a rapid global distribution network. Our main production laboratories are located in Switzerland, the UK, Slovakia and China, with peptide and antibody production in the US, the Netherlands. Bioconjugation projects are carried out in Germany, Enzyme projects are based in Austria and biological IVD reagents in Ireland.
Recruitment agencies - we are unable to accept unsolicited CVs and communications from external recruiters. We do not use recruitment agencies to recruit for our roles.
