Higher or Senior Scientific Officer (Basé à London)

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Key Information

Salary: Salary from 39,805 to 49,023

Reporting to: Prof Trevor Graham

Duration of Contract: Fixed Term for 2 years

Hours per week: 35 hours per week (Full Time)

Location: Sutton

Closing Date: 28th April 2025

Job Details

Under the guidance of Prof Trevor Graham, we are seeking to recruit a Higher or Senior Scientific Officer to study epigenome evolution in colorectal cancer. The successful candidate will play a key role in undertaking research into the evolutionary dynamics that underpin colorectal cancer development and response to treatment. The post holder will lead experimental lab work to generate and analyse molecular genomics data, especially single cell data, from patient material and other sample types.

About you

The successful candidate must have:

• PhD in molecular biology or other relevant area.
• Ability to perform advanced NGS experiments for the analysis of cancer genomes.
• Ability to conduct single cell/nuclei dissociation, sorting and NGS analysis in cell lines and/or patient biopsies.
• Proven expertise in advanced NGS technologies, including RNA-seq, DNA-seq, and single-cell sequencing.
• Hands-on experience with single-cell technologies such as scRNA-seq, scATAC-seq, or spatial transcriptomics.
• Good communication skills and the ability to interact effectively with other team members.

Department/Directorate Information

The Centre for Evolution and Cancer (CEC), within the Division of Cancer Biology, is a multidisciplinary centre, comprising around 50 staff dedicated to understanding cancer evolution and leveraging this knowledge for translational benefit. Our interests span early detection through to treatment of metastatic disease. The CEC brings together expertise in evolutionary theory, computational biology and bioinformatics together with cutting-edge research ability in cell and molecular biology to provide a stimulating and creative interdisciplinary environment where new approaches to tackling cancer can thrive.

The Genomics and Evolutionary Dynamics team combine molecular and cellular biology together with mathematical and computational modelling to study the evolution of malignancy. We focus on early detection in the gastrointestinal tract, colorectal cancer evolution and treatment response, and pan-cancer genomics. We perform basic research into the biology of the human body in health and disease and translate our findings to improve clinical care of patients affected by cancer.

What we offer

• A dynamic and supportive research environment.
• Access to state-of-the-art facilities and professional development opportunities.
• Collaboration with leading researchers in the field.
• Competitive salary and pension.

We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Prof Trevor Graham at [email protected].

About The Institute of Cancer Research

Why work for us?

As a member of staff, you'll have exclusive access to a range of staff benefits.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.

We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.

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